Zobrazeno 1 - 8
of 8
pro vyhledávání: '"S. W. Carper"'
Publikováno v:
Journal of cellular biochemistry. 66(2)
Constitutive expression of human hsp27 resulted in a 100-fold increase in survival to a single lethal heat shock in CHO cells without effecting the development of thermotolerance. A possible mechanism for the thermoprotective function of hsp27 may be
Autor:
S. W. Carper, David J. M. Fuller, Paul M. Harari, Margaret E. Tome, Jung-Ren Chen, Eugene W. Gerner
N1-Acetylspermidine (N1AcSpd) accumulates in late exponential phase, or after certain stresses such as heat shock, in both human tumour (A549) and rodent (HTC, CHO) cells, grown in medium containing an inhibitor of the FAD-dependent polyamine oxidase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfd866becf0441b464fdc17e84a0e89a
https://europepmc.org/articles/PMC1130544/
https://europepmc.org/articles/PMC1130544/
Publikováno v:
The Journal of biological chemistry. 266(19)
Heat shock, cold shock, ethanol, and alkaline shift, but not hydrogen peroxide, stimulate the accumulation of monoacetylspermidine in Escherichia coli. Acetylation occurs with nearly equal frequencies at both the N1 and N8 positions of this ubiquitou
Autor:
F. K. Storm, S. W. Carper
Publikováno v:
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 7(3)
Tetraplatin is a second-generation platinum analogue that will be introduced into clinical trials during 1990. We have evaluated the cytotoxicity of tetraplatin and its stereoisomers under a variety of conditions in a human solid tumour cell line (A5
Autor:
David J. M. Fuller, Frank L. Meyskens, Marilyn K. Croghan, David S. Shimm, S. W. Carper, Paul M. Harari, Eugene W. Gerner
Publikováno v:
Harari, PM; Fuller, DJ; Carper, SW; Croghan, MK; Meyskens, FL; Shimm, DS; et al.(1990). Polyamine biosynthesis inhibitors combined with systemic hyperthermia in cancer therapy.. International journal of radiation oncology, biology, physics, 19(1), 89-96. doi: 10.1016/0360-3016(90)90139-b. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/1wt2d2kq
A Phase I clinical trial has been initiated at the University of Arizona Cancer Center which combines escalating oral doses of the polyamine biosynthesis inhibitor alpha-difluoromethylornithine (DFMO), with systemic hyperthermia (approximately 41.5 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e593b9b3d8a323a579c43b632457d02c
http://www.escholarship.org/uc/item/1wt2d2kq
http://www.escholarship.org/uc/item/1wt2d2kq
Publikováno v:
Biochemical Journal. 260:487-490
In exponential-phase Chinese-hamster cells, 0.1 mM-diethyldithiocarbamate (DDC) afforded greater than 1 log survival protection to cultures treated before and during exposure to 1 mM-H2O2. Both DDC and H2O2 treatment stimulated the activity of ornith
Publikováno v:
Proceedings of the National Academy of Sciences. 82:6793-6796
Intracellular ATP levels in whole cells of Methanococcus voltae respond to electron transfer coupled to methanogenesis. ATP synthesis can also be induced by an artificially imposed transmembrane electrical potential [formed by electrogenic movement o
Publikováno v:
Cancer research. 47(20)
Heat shock proteins appear to be causatively involved in the acquisition of thermotolerance in prokaryotes but not in eukaryotes. Further, the enhanced synthesis of hsps may be necessary for some cellular responses to stress but not others. In prokar