Zobrazeno 1 - 10
of 34
pro vyhledávání: '"S. Vinuesa"'
Publikováno v:
The Journal of Organic Chemistry. 58:5186-5191
Various cyanomethyleneamino pseudodipeptides were easily prepared in high yield by the Lewis acid catalyzed addition of trimethylsilyl cyanide to unstable aldimine intermediates, obtained from the reaction of N-protected α-amino aldehydes with C-pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::091a79ece1860a2f3e263a857ef7fb77
https://doi.org/10.1021/jo00071a031
https://doi.org/10.1021/jo00071a031
Autor:
Cirilo Pérez, Ma Teresa García-López, Isabel Gomez-Monterrey, Julia Castro-Pichel, Rosario Herranz, S. Vinuesa
Publikováno v:
Archiv der Pharmazie. 326:395-398
The synthesis of (6R,5S,2RS)-6-amino-5-hydroxy-2-isobutyl-4-oxo-7- phenylheptanoic acid (9), a carbaanalogue of the aminopeptidase (AP) inhibitor bestatin (1) is described. This synthesis was carried out by a malonic ester alkylation with the suitabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f3b654d5de2847a8f92fe5374156c3
https://doi.org/10.1002/ardp.19933260705
https://doi.org/10.1002/ardp.19933260705
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1020b81c5f132468219aeea9d8ebd99e
https://doi.org/10.1002/chin.199246235
https://doi.org/10.1002/chin.199246235
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::008b7935e6b60fbffd05fb3a5c230af3
https://doi.org/10.1002/chin.199401271
https://doi.org/10.1002/chin.199401271
Autor:
J. Del Rio, Enriqueta R. López, Cándido González Pérez, M.L. De Ceballos, Rosario Herranz, M. T. Garcia‐Lopez, S. Vinuesa
Publikováno v:
Journal of Medicinal Chemistry. 35:889-895
A series of diastereomeric dipeptides, analogues of the analgesic compound H-Lys-Trp(Nps)-OMe (2), containing 3,7-diamino-2-hydroxyheptanoic acid (DAHHA) and 2-[(o-nitrophenyl)sulfenyl]tryptophan [Trp(Nps)] has been synthesized. These compounds were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c9e7e5497c3a69c6c0745d07f519f59
https://doi.org/10.1021/jm00083a013
https://doi.org/10.1021/jm00083a013
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :1825-1830
The synthesis of aminodeoxybestatin and epi-aminodeoxybestatin [(2S,3R)- and (2R,3R)-2,3-di-amino-4-phenylbutanoyl-L-leucine; (2S,3R)- and (2R,3R)-DAPBA-L-Leu)], bestatin and epi-bestatin analogues, respectively, in which the hydroxy group has been r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6a0c8ac321086f2f6cdb1e21dd1a2a7
https://doi.org/10.1039/p19920001825
https://doi.org/10.1039/p19920001825
Autor:
Concepción Pérez, María L. de Ceballos, Joaquin Del Rio, S. Vinuesa, Rosario Herranz, Francisco M. Murillo, M. Teresa García-López
Publikováno v:
Archiv der Pharmazie. 325:515-518
(2S,3R)-3,7-Diamino-2-hydroxy-heptanoyl-Leu-Pro-OH [(2S,3R)-DAHHA-Leu-Pro-OH, 4], analogue of the N-terminal tripeptide of probestin, has been synthesized, and tested as inhibitor of AP-B, Leu-AP, AP-M, and enkephalin-degrading APs, and as analgesic.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f345b7db9db4b2fa08b29933fa820d2
https://doi.org/10.1002/ardp.19923250812
https://doi.org/10.1002/ardp.19923250812
Publikováno v:
Tetrahedron Letters. 32:7579-7582
An easy and versatile general method for the preparation of the new peptide bond surrogate Ψ[CH(CN)NH], by the Lewis acid catalyzed reaction of N-protected α-amino aldehydes with a C-protected amino acid or peptide in the presence of TMSCN, is desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b136b8354dc7e299dc21f8de651ad3a9
https://doi.org/10.1016/0040-4039(91)80539-i
https://doi.org/10.1016/0040-4039(91)80539-i
Autor:
Concepción Pérez, María L. de Ceballos, M. Teresa García-López, Rosario Herranz, Joaquín Del Río, S. Vinuesa
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scopus-Elsevier
instname
Scopus-Elsevier
A series of diastereoisomeric dipeptides, analogues of the analgesic compound H-Trp(Nps)-Lys-OMe, containing 3-amino-2-hydroxy-4-[2-(o- nitrophenylthio)indol-3-yl]butanoic acid [AH(Nps)IBA] and Lys or Leu has been synthesized. These compounds were te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ed3fa5ee3adc347834dc55ffd03964
https://doi.org/10.1039/p19910002749
https://doi.org/10.1039/p19910002749
