Zobrazeno 1 - 10
of 470
pro vyhledávání: '"S. Van Drunen Littel-Van Den Hurk"'
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 12, Pp 2894-2901 (2017)
Respiratory syncytial virus (RSV) is the most common cause of respiratory tract infections in both children and elderly people. In this study we evaluated the short- and long-term protective efficacy of a single intranasal (IN) immunization with a RS
Externí odkaz:
https://doaj.org/article/da41b3461cbe4d3c87239391be8e3723
Autor:
S. van Drunen Littel-van den Hurk, Ravendra Garg, Andrew A. Potter, Susantha Gomis, Laura J.P. Latimer, Volker Gerdts
Publikováno v:
Antiviral Research. 162:54-60
Human parainfluenza virus 3 (PIV3) and respiratory syncytial virus (RSV) are major causative agents of serious respiratory tract illness in newborns and infants. Maternal vaccination could be a promising approach to provide immediate protection again
Autor:
S. van Drunen Littel-van den Hurk, Volker Gerdts, Andrew A. Potter, Ravendra Garg, Robert Brownlie, Laura J.P. Latimer
Publikováno v:
Vaccine. 35:7139-7146
Human parainfluenza virus type 3 (PIV3) is a major cause of lower respiratory disease i.e. bronchitis, bronchiolitis or pneumonia, in infants and young children. Presently there is no licensed vaccine against PIV3. To produce an effective subunit vac
Autor:
Volker Gerdts, Ravendra Garg, Andrew A. Potter, S. van Drunen Littel-van den Hurk, Laura J.P. Latimer
Publikováno v:
Human Vaccines & Immunotherapeutics
Respiratory syncytial virus (RSV) is the most common cause of respiratory tract infections in both children and elderly people. In this study we evaluated the short- and long-term protective efficacy of a single intranasal (IN) immunization with a RS
Autor:
Laura J.P. Latimer, Robert Brownlie, Andrew A. Potter, Volker Gerdts, S. van Drunen Littel-van den Hurk, Ravendra Garg
Publikováno v:
Antiviral research. 158
Human respiratory syncytial virus (RSV) and parainfluenza virus type 3 (PIV3) are major causes of serious lower respiratory tract disease in infants. Currently there is no licensed vaccine against RSV or PIV3. To make an effective bivalent subunit va
Autor:
Ravendra Garg, Y. Wang, Volker Gerdts, Elemir Simko, S. van Drunen Littel-van den Hurk, Andrew A. Potter, Laura J.P. Latimer
Publikováno v:
Vaccine. 34:261-269
Respiratory syncytial virus (RSV) is the causative agent of serious upper and lower respiratory tract infections in newborns and infants. Protection from RSV is crucial for neonates, and maternal immunization is one approach that holds promise for pr
Autor:
Volker Gerdts, S. van Drunen Littel-van den Hurk, Andrew A. Potter, Laura J.P. Latimer, Ravendra Garg
Publikováno v:
Journal of General Virology. 95:1043-1054
Respiratory syncytial virus (RSV) is one of the primary causative agents of upper and lower respiratory tract infections in young children, in particular infants. Recently, we reported the protective efficacy of a RSV vaccine formulation consisting o
Publikováno v:
Journal of Viral Hepatitis. 18:700-713
Summary. Hepatitis C virus (HCV) causes a chronic liver infection, which may result in cirrhosis and hepatocellular carcinoma. Impairment of the maturation process in dendritic cells (DCs) may be one of the mechanisms responsible for immune evasion o
Autor:
Laura Latimer, S. van Drunen Littel-van den Hurk, Lorne A. Babiuk, Jennifer Kovacs-Nolan, J. W. Mapletoft
Publikováno v:
Vaccine. 27:2048-2054
Vaccines consisting of subunit or protein antigens are less immunogenic than traditional vaccines, and therefore require formulation with an adjuvant. Conventional adjuvants, however, often cause undesirable injection site reactions and Th2-biased im
Autor:
Antonio Joao Ubach, Donald Wilson, Drew Hannaman, Alain Luxembourg, S. van Drunen Littel-van den Hurk, Barry Ellefsen, J. V. van den Hurk
Publikováno v:
Vaccine. 26:5503-5509
Despite the potential of DNA vaccines to induce strong, balanced immune responses in small experimental species, the immune responses to DNA immunization in larger species have generally been moderate and inconsistent. In this study, the TriGrid™ D