Stress and Corticosteroids Aggravate Morphological Changes in the Dentate Gyrus after Early-Life Experimental Febrile Seizures in Mice

Autor: Jolien S. van Campen, Ellen V. S. Hessel, Kirsten Bohmbach, Giorgio Rizzi, Paul J. Lucassen, Sada Lakshmi Turimella, Eduardo H. L. Umeoka, Gideon F. Meerhoff, Kees P. J. Braun, Pierre N. E. de Graan, Marian Joëls

Publikováno v: Frontiers in Endocrinology, Vol 9 (2018)

Stress is the most frequently self-reported seizure precipitant in patients with epilepsy. Moreover, a relation between ear stress and epilepsy has been suggested. Although ear stress and stress hormones are known to influence seizure threshold in ro

Externí odkaz: https://doaj.org/article/cb2cd330eec9443cb441d84d3bce8e63

Photosensitivity in Dravet syndrome is under-recognized and related to prognosis

Autor: Anja C M Sonsma, Al W. de Weerd, Dorothée G.A. Kasteleijn-Nolst Trenité, Nine V A M Knoers, Frans S. S. Leijten, Merel Wassenaar, Thea Gutter, W. Boudewijn Gunning, Jolien S. van Campen, Nienke E. Verbeek, Willy P. J. Spetgens, Eva H. Brilstra

Publikováno v: Clinical Neurophysiology, 128(2), 323-330. ELSEVIER IRELAND LTD
Clinical Neurophysiology, 128(2), 323. Elsevier Ireland Ltd

Objective: To detect determinants for photoparoxysmal EEG response (PPR) in SCN1A -related Dravet syndrome (DS). Methods: Data were studied from nationwide medical histories and EEGs of DS-patients ( n =53; 31 males, age 2–19years). Detailed questi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994163b3fda7c88f2ac77b9a5e1c075e
https://doi.org/10.1016/j.clinph.2016.11.021

Cortisol fluctuations relate to interictal epileptiform discharges in stress sensitive epilepsy

Autor: E. Lorraine Hompe, Kees P.J. Braun, Willem M. Otte, Jolien S. van Campen, Maeike Zijlmans, Gerhard H. Visser, Floor E. Jansen, Fia van de Berg, Marian Joëls, Demetrios N. Velis, Josemir W. Sander

Publikováno v: Brain, 139(6), 1673. Oxford University Press
Brain, 139, 1673-1679. Oxford University Press
van Campen, J S, Hompe, E L, Jansen, F E, Velis, D N, Otte, W M, van de Berg, F, Braun, K P J, Visser, G H, Sander, J W, Joels, M & Zijlmans, M 2016, ' Cortisol fluctuations relate to interictal epileptiform discharges in stress sensitive epilepsy ', Brain, vol. 139, pp. 1673-1679 . https://doi.org/10.1093/brain/aww071

People with epilepsy often report seizures precipitated by stress. This is believed to be due to effects of stress hormones, such as cortisol, on neuronal excitability. Cortisol, regardless of stress, is released in hourly pulses, whose effect on epi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c8f68a8942248dc8e3d3f1bda2a830
https://doi.org/10.1093/brain/aww071

Behavioral disinhibition and antiepileptic treatment in childhood epilepsy: A retrospective cohort study

Autor: Kees P.J. Braun, Floor E. Jansen, Jolien S. van Campen, Hilgo Bruining, Chantal Vlaskamp, Diana C. van Tuijl, Rolf H.H. Groenwold

Publikováno v: Epilepsia Open, 2(1), 59. Wiley-Blackwell Publishing Ltd
Epilepsia Open

Summary Objective To test whether specific classes of antiepileptic drugs increase the risk for behavioral disinhibition, a frequent complication of treatment of childhood epilepsy. Methods In a sample of children with active epilepsy and antiepilept

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf88c6a6365584e10c7eebef9bb572c
https://dspace.library.uu.nl/handle/1874/351268

Interobserver agreement of the old and the newly proposed ILAE epilepsy classification in children

Autor: Kees P.J. Braun, Jolien S. van Campen, Joost Nicolai, Oebele F. Brouwer, Floor E. Jansen

Publikováno v: Epilepsia, 54(4), 726-732. Wiley

Purpose Accurate classification of epileptic seizures, epilepsies, and epilepsy syndromes is mandatory in both clinical practice and epilepsy research. In 2010, the International League Against Epilepsy (ILAE) proposed a new classification scheme. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8529fed938d89fed0858bd8e3be6ce8
https://cris.maastrichtuniversity.nl/en/publications/52b01acb-5844-4d6e-939d-218e6a2173dd