Zobrazeno 1 - 10
of 11
pro vyhledávání: '"S. V. Yarotsky"'
Publikováno v:
Applied Biochemistry and Microbiology. 58:251-260
Abstract The processes of the biocatalytic acylation of 1-methyl-5-mercapto-1,2,3,4-tetrazolil-7-amino-cephalosporanic acid (7-TMCA) and 7-aminocephalosporanic acid (7-ACA) by methyl ester of mandelic acid (MEMA) were optimized with an immobilized ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a9db07b2f085ae98c9104b40dfbd12e
https://doi.org/10.1134/s0003683822030127
https://doi.org/10.1134/s0003683822030127
Publikováno v:
Applied Biochemistry and Microbiology. 56:526-537
Two pathways of combined chemical and biocatalytic synthesis of the antibiotic cefazolin (CEZ) from 7-amino-cephalosporanic acid (7-ACA) with the immobilized recombinant cephalosporin-acid synthetase as the biocatalyst are compared. The first pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d1b76bbd6d08dd92365717e5a832338
https://doi.org/10.1134/s0003683820050130
https://doi.org/10.1134/s0003683820050130
Autor:
E. P. Sannikova, V. L. Yurin, D. G. Kozlov, N. V. Bobkova, E. V. Askerova, T. S. Gracheva, F. A. Klebanov, Gosniigenetika , Moscow Russia, N. V. Rykalina, N. V. Bulushova, S. V. Yarotsky, S. E. Cheperegin, I. A. Zalunin, O. G. Tatarnikova
Publikováno v:
Biotekhnologiya. 34:37-50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ae554ceaebdea9c54a01012c370a72f
https://doi.org/10.21519/0234-2758-2018-34-4-37-50
https://doi.org/10.21519/0234-2758-2018-34-4-37-50
Publikováno v:
Tsitologiya. 60:567-571
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35149b87ef5eee783bc2a38ddf7c22aa
https://doi.org/10.31116/tsitol.2018.07.16
https://doi.org/10.31116/tsitol.2018.07.16
Autor:
E. K. Kotlova, E. P. Sannikova, Vadim S. Pokrovsky, T. S. Kubasova, I. I. Gubaydullin, G. E. Konstantinova, N. V. Bulushova, V. V. Ryabichenko, S. V. Yarotsky, I. A. Zalunin, G. G. Chestukhina, Alexander A. Shtil, B. D. Efremov, S. E. Cheperegin, D. G. Kozlov
Publikováno v:
Molecular Biotechnology. 58:528-539
The modified asparaginase Was79 was derived from the recombinant wild-type L-asparaginase of Wolinella succinogenes. The Was79 contains the amino acid substitutions V23Q and K24T responsible for the resistance to trypsinolysis and the N-terminal hepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bedb461e2ebc4a06a568f909c3b895f
https://doi.org/10.1007/s12033-016-9950-1
https://doi.org/10.1007/s12033-016-9950-1
Publikováno v:
Bioprocess and biosystems engineering. 41(12)
A method for the synthesis of β-lactam antibiotic cefazolin (CEZ) by enzymatic acylation of 7-amino-3-(5-methyl-l,3,4-thiadiazol-2-yl)thiomethyl-3-cephem-4-carboxylic acid (TDA) using immobilized cephalosporin-acid synthetase (IECASA) from recombina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61c413e275021383bc3e9c2c17fab60
https://pubmed.ncbi.nlm.nih.gov/30244423
https://pubmed.ncbi.nlm.nih.gov/30244423
Publikováno v:
Applied Biochemistry and Microbiology. 51:627-640
The currently known methods of enzymatic β-lactam synthesis, as well as the enzymes and heterogeneous biocatalysts used for this purpose, are presented, and the published reports on advances in the field of enzymatic synthesis of selected antibiotic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43b1eade329880135e99a514e820a572
https://doi.org/10.1134/s0003683815060150
https://doi.org/10.1134/s0003683815060150
Autor:
O. V. Berezina, S. V. Yarotsky, E. A. Fedorchuk, Vladimir I. Tishkov, A. V. Sklyarenko, V. V. Fedorchuk, S. S. Savin, D. E. Satarova
Publikováno v:
Moscow University Chemistry Bulletin. 69:62-67
Recombinant, as well as native alpha-amino acid ester hydrolase from Xanthomonas rubrilineans VKPM B-9915 (XrAEH, EC 3.1.1.43), was tested for synthesis of amino-beta-lactam antibiotic cephalexin. It was shown that the recombinant enzyme r-XrAEH prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::664242b85f02bb51bcc463cec04536df
https://doi.org/10.3103/s0027131414020084
https://doi.org/10.3103/s0027131414020084
Autor:
Vladimir I. Tishkov, S. A. Zarubina, A. V. Sklyarenko, V. V. Fedorchuk, E. A. Fedorchuk, I. V. Uporov, S. V. Yarotsky
Publikováno v:
Scopus-Elsevier
Acta Naturae
Acta Naturae
Alpha-amino acid ester hydrolase (EC 3.1.1.43, AEH) is a promising biocatalyst for the production of semi-synthetic -lactam antibiotics, penicillins and cephalosporins. The AEH gene from Xanthomonas rubrilineans (XrAEH) was recently cloned in this la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e422293eaa985d9122834c38edba6d83
https://doi.org/10.32607/20758251-2013-5-4-62-70
https://doi.org/10.32607/20758251-2013-5-4-62-70
Publikováno v:
Bioprocess and Biosystems Engineering. 34:1103-1117
The article deals with experimental determination of ionization constants and solubility for the compounds (target products, initial β-lactams, acylating agents and by-products) involved in enzymatic synthesis of some therapeutically used aminopenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d697b8180214dd4d223ef85f8d1391a
https://doi.org/10.1007/s00449-011-0560-9
https://doi.org/10.1007/s00449-011-0560-9