Zobrazeno 1 - 5
of 5
pro vyhledávání: '"S. V. Ustinkina"'
Autor:
M. P. Kiseleva, L. M. Borisova, V. V. Delektorskaya, Z. S. Shprakh, S. V. Ustinkina, I. Yu. Kubasova
Publikováno v:
Russian Journal of Biotherapy. 21:50-60
Background. Expression evaluation of somatostatin receptors (SSTRs) in tumor cells is necessary for the reasonable use of therapy directed at such receptors.Aim. The affinity determination of the original analogue of somatostatin cyphetrylin for SSTR
Autor:
L. M. Borisova, M. P. Kiseleva, S. V. Ustinkina, L. P. Sushinina, L. I. Smirnova, Z. S. Shprakh, T. A. Sidorova, A. P. Smirnova
Publikováno v:
Russian Journal of Biotherapy. 16:63-68
Background. The purpose of this investigation is the search of new compounds with high selectivity of antitumor action on the tumor of the gastrointestinal tract (GIT) in the series of analogues of the peptide hormone gastrin. Objective: synthesis of
Autor:
L. M. Borisova, M. P. Kiseleva, V. N. Osipov, L. P. Sushinina, S. V. Ustinkina, L. I. Smirnova, Z. S. Shprakh
Publikováno v:
Russian Journal of Biotherapy. 16:23-29
Autor:
L. M. Borisova, M. P. Kiseleva, V. N. Osipov, L. I. Smirnova, S. V. Ustinkina, Z. S. Shprakh, L. P. Sushinina
Publikováno v:
Russian Journal of Biotherapy. 15:85-88
Background. The drug cyphetrylin, hypothalamic hormone somatostatin analogue, was developed in N.N. Blokhin Russian Cancer Research Center at the Ministry of Health of Russia. The basis of this work is the idea of using cyphetrylin as a specific carr
Autor:
S. V. Ustinkina, Z. S. Shprakh, A. P. Bud'ko, L. P. Sushinina, I. V. Yartseva, A. P. Smirnova, L. I. Smirnova, N. I. Zimakova, E. V. Ignat’eva
Publikováno v:
Pharmaceutical Chemistry Journal. 48:159-162
An analog of somatostatin with hormonal and antitumor activity was synthesized. An optimum synthesis method was developed, yielding standard pharmaceutical somatostatin analog substance for preclinical and clinical studies. A quality control method w