Zobrazeno 1 - 10
of 28
pro vyhledávání: '"S. V. Popkov"'
Publikováno v:
Тонкие химические технологии, Vol 14, Iss 3, Pp 60-69 (2019)
The article proposes an approach for obtaining the derivatives of hetarylmethylthioaryloxyalcane PPARS/fi agonists containing sulfoxide and sulfone fragments in the linker, the parent compound for the synthesis being GSK-516 - (2-methyl-4-[4-methyl-2
Externí odkaz:
https://doaj.org/article/45652230902749589cf993138bbbc44f
Publikováno v:
Russian Journal of Organic Chemistry. 59:207-223
Autor:
G. V. Tsaplin, S. V. Popkov
Publikováno v:
Russian Journal of Organic Chemistry. 58:1-14
Publikováno v:
Pharmaceutical Chemistry Journal. 55:142-148
Metabolites of β2-agonists 2-(4-amino-3,5-dichlorophenyl)-2-(alkylamino)ethanols, derivatives of hippuric and mandelic acids, were synthesized. The excretion profiles of the target compounds and metabolites with urine were studied in experiments on
Autor:
O.G. Karmanova, S.S. Grishin, E.P. Baberkina, S. V. Popkov, V.S. Talismanov, G.V. Tsaplin, S.S. Zykova
Publikováno v:
Rasayan Journal of chemistry. 14:1816-1820
Autor:
S. V. Popkov, L.A. Zhuravleva, M.V. Shustov, V.S. Talismanov, N.G. Tokareva, O.G. Karmanova, S.S. Zykova
Publikováno v:
Rasayan Journal of chemistry. 14:1711-1716
Publikováno v:
Pharmaceutical Chemistry Journal. 54:694-699
Methods for the synthesis of 2-(4-amino-3,5-dichlorophenyl)-2-(isopropylamino)ethanol and 2-(4-amino-3,5-dichlorophenyl)-2-(tert-amylamino)ethanol, which are structural isomer of the β2 agonists clenproperol and clenpenterol, were developed. The pha
Publikováno v:
Russian Journal of Organic Chemistry. 56:390-394
Alternative methods have been developed for the synthesis of the β2-agonist tulobuterol and its metabolite 4-hydroxytulobuterol with a similar activity. The proposed procedures utilize available reagents, and the key stage in the synthesis is the fo
Publikováno v:
Тонкие химические технологии, Vol 14, Iss 3, Pp 60-69 (2019)
The article proposes an approach for obtaining the derivatives of hetarylmethylthioaryloxyalcane PPARS/fi agonists containing sulfoxide and sulfone fragments in the linker, the parent compound for the synthesis being GSK-516 - (2-methyl-4-[4-methyl-2
Publikováno v:
Russian Journal of General Chemistry. 87:1702-1706
Intramolecular cyclization of N-aryl-2-[(9-oxoacridin-10(9H)-yl)acetyl]hydrazinecarboxamides afforded new 10-(5-arylamino-1,3,4-oxadiazol-2-ylmethyl)acridin-9(10H)-ones. Some of the synthesized compounds showed a moderate antimicrobial activity again