Zobrazeno 1 - 10
of 61
pro vyhledávání: '"S. V. Kruglov"'
Autor:
T. A. Antipova, I. O. Logvinov, S. V. Nikolaev, S. V. Kruglov, A. V. Tarasiuk, P. I. Antipov, T. A. Gudasheva, S. B. Seredenin
Publikováno v:
Фармакокинетика и Фармакодинамика, Vol 0, Iss 2, Pp 14-17 (2016)
On culture of hippocampal HT-22 cells line it is shown that dimeric dipeptide mimetiks of different Loops of NGF realize their action via specific neurotrophic TrkA-receptor and selective activate post-receptor intracellular signal ways. Mimetiks of
Externí odkaz:
https://doaj.org/article/e196399e3ccb4e7e86fdadb54fb902b5
Autor:
V. S. Zadionchenko, N. B. Holodkova, O. I. Nesterenko, I. V. Pogonchenkova, A. M. Shchikota, Y. V. Ignatova, I. Y. Malyshev, E. B. Manukhina, S. V. Kruglov, D. A. Pokidyshev, O. A. Zemnina
Publikováno v:
Рациональная фармакотерапия в кардиологии, Vol 3, Iss 2, Pp 48-52 (2015)
Aim. To evaluate intensity of endothelial dysfunction, processes of apoptosis, state of central and peripheral hemodynamics and to evaluate how these characteristics are influenced by angiotensin II receptors antagonists (ARA II) – candesartan (Ata
Externí odkaz:
https://doaj.org/article/0f0070b05f384d689b2a477e8f90a73d
Autor:
P. V. Pugach, S. V. Kruglov
Publikováno v:
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, Vol 21, Iss 3, Pp 47-50 (2014)
The investigation was carried out on the white outbred female rats (n = 80) which were being under the influence of15 % solution of ethanol during pregnancy, from the first to the sixth months before its approach and on their viable posterity (n = 44
Externí odkaz:
https://doaj.org/article/e692375609a8469bae5736e58860af5b
Autor:
S. V. Kruglov, S. V. Lyamina, T. Yu. Vedenikin, O. A. Borodovizyna, I. A. Suvorova, Sh. L. Shimshelashvili, I. Yu. Malyshev
Publikováno v:
Медицинская иммунология, Vol 14, Iss 1-2, Pp 127-132 (2014)
Abstract. Macrophages are among key players of inflammatory events, acquiring either pro-inflammatory M1, or anti-inflammatory M2 phenotype, dependent on their microenvironment. Some endogenous macrophagereprogramming factors (MRFs), e.g., TGF-β (an
Externí odkaz:
https://doaj.org/article/8c2936a189624bf6a5a273d24a29c3a9
Autor:
V. V. Mulenko, S. V. Kruglov, V. G. Timoshenko, Kh. A. Tumanyan, M. A. Mokhov, M. A. Frankov, Yu. A. Sazonov
Publikováno v:
Journal of Computational and Theoretical Nanoscience. 16:4573-4578
The research is aimed at the development of new scientific principles for the creation of special pumping equipment for the extraction of oil and gas in complicated conditions. In many cases, the complicated operating conditions of the pump are deter
Publikováno v:
Journal of Computational and Theoretical Nanoscience. 16:2815-2821
Autor:
A. V. Muradov, M. A. Frankov, Kh. A. Tumanyan, M. A. Mokhov, S. V. Kruglov, Iuri Appolonievich Sazonov
Publikováno v:
Journal of Computational and Theoretical Nanoscience. 16:3007-3012
Autor:
P. Yu. Povarnina, S. B. Seredenin, A. A. Volkova, S. V. Kruglov, T. A. Antipova, Tatiana A Gudasheva
Publikováno v:
Acta Naturae
The nerve growth factor (NGF) and its mimetics, which have neuroprotective and neuroregenerative properties, are attractive candidates for developing new drugs for brain injury therapy. A dipeptide mimetic of NGF loop 4, bis(N-succinyl-L-glutamyl-L-l
Autor:
Polina Povarnina, I. O. Logvinov, S. V. Kruglov, Sergey B. Seredenin, Dmitry M. Nikiforov, Tatiana A. Antipova, Tatiana A Gudasheva
Publikováno v:
CNSneurological disorders drug targets. 20(10)
Background: A dimeric dipeptide mimetic of the BDNF loop 4, bis(N-monosuccinyl- L-seryl-L-lysine) hexamethylenediamide (GSB-106) activates TrkB, PI3K/AKT, MAPK/ ERK, and PLC-γ1, and was created at the V.V. Zakusov Research Institute of Pharmacology.
Autor:
Tatiana A Gudasheva, S. B. Seredenin, L. G. Kolik, A. V. Nadorova, S V Kruglov, M. A. Konstantinopolsky, T. A. Antipova
Publikováno v:
Bulletin of experimental biology and medicine. 170(1)
Activity of compound GSB-106, a low-molecular mimetic of loop 4 of the brain neurotrophic factor (BDNF), was studied in experimental morphine withdrawal syndrome simulated in outbred rats. Single and subchronic (5 intraperitoneal injections) administ