Zobrazeno 1 - 6
of 6
pro vyhledávání: '"S. V. Kovaltsova"'
Autor:
S. V. Kovaltsova, T. A. Evstuhina, V. T. Peshekhonov, V. G. Korolev, D. V. Fedorov, A. Yu. Chernenkov
Publikováno v:
Russian Journal of Genetics. 49:286-293
Previously, we isolated mutant yeasts Saccharomyces cerevisiae with an increased rate of spontaneous mutagenesis. Here, we studied the properties of HSM6 gene, the hsm6-1 mutation of which increased the frequency of UV-induced mutagenesis and decreas
Autor:
S. V. Kovaltsova, L. M. Gracheva, D. V. Fedorov, T. A. Evstuhina, V. G. Korolev, A. Yu. Chernenkov, V. T. Peshekhonov, I. V. Fedorova
Publikováno v:
Russian Journal of Genetics. 48:284-290
It was assumed previously that the mutator phenotype of the hms3 mutant was determined by processes taking place in the D-loop. As a next step, genetic analysis was performed to study the interactions between the hsm3 mutation and mutations of the ge
Autor:
T. A. Evstyukhina, A. Yu. Chernenkov, L. M. Gracheva, I. V. Fedorova, V. G. Korolev, V. T. Peshekhonov, S. V. Kovaltsova
Publikováno v:
Russian Journal of Genetics. 48:139-145
In eukaryotes, damage tolerance of matrix DNA is mainly determined by the repair pathway under the control of the RAD6 epistatic group of genes. This pathway is also a main source of mutations generated by mutagenic factors. The results of our recent
Publikováno v:
Russian Journal of Genetics. 44:1272-1279
Geptrong is a medication from pure defermentated honey. In medical practice, it is used as hepatoprotector. Genotoxicity analysis revealed antimutagenic activity of the preparation. The spontaneous mutation rate at the ADE4-ADE8 and CAN1 loci was sev
Publikováno v:
Russian Journal of Genetics. 43:84-87
Sensitivity to the lethal action of the anticancer substance cisplatin was studied in the yeast mutants him1, hsm2, hsm3, and hsm6, deficient for repair of spontaneous and induced mutations. The him1 and hsm3 mutants were as resistant to the agent un
Autor:
Irina V. Fedorova, S. V. Kovaltsova, V. T. Peshekhonov, T.A. Evstukhina, S.Yu. Alekseev, L. M. Gracheva, Vladimir G. Korolev
Publikováno v:
DNA repair. 1(4)
We have previously reported about a new Saccharomyces cerevisiae mutation, hsm2-1, that results in increase of both spontaneous and UV-induced mutation frequencies but does not alter UV-sensitivity. Now HSM2 gene has been genetically and physically m