Zobrazeno 1 - 10
of 73
pro vyhledávání: '"S. Tupper"'
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 5, p e1012139 (2024)
Recent pandemics like COVID-19 highlighted the importance of rapidly developing diagnostics to detect evolving pathogens. CRISPR-Cas technology has recently been used to develop diagnostic assays for sequence-specific recognition of DNA or RNA. These
Externí odkaz:
https://doaj.org/article/bc0a6316d5b94ecaa08d92cfccb39a66
Publikováno v:
Life, Vol 9, Iss 3, p 65 (2019)
In RNA-World scenarios for the origin of life, replication is catalyzed by polymerase ribozymes. Replicating RNA systems are subject to invasion by non-functional parasitic strands. It is well-known that there are two ways to avoid the destruction of
Externí odkaz:
https://doaj.org/article/5c2467eb1b594e46a781618dbc9bf965
Publikováno v:
Molecular Biology and Evolution. 37:71-83
Most scenarios for the origin of life assume that RNA played a key role in both catalysis and information storage. The A, U, G, and C nucleobases in modern RNA all participate in secondary structure formation and replication. However, the rapid deami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e4af9342ad03627170a2315e638f6a
https://doi.org/10.1093/molbev/msz200
https://doi.org/10.1093/molbev/msz200
Publikováno v:
Life, Vol 7, Iss 4, p 41 (2017)
Biological RNA is a uniform polymer in three senses: it uses nucleotides of a single chirality; it uses only ribose sugars and four nucleobases rather than a mixture of other sugars and bases; and it uses only 3′-5′ bonds rather than a mixture of
Externí odkaz:
https://doaj.org/article/4a7fedced15e4c6896c722026e0f5b68
Autor:
Bigelow, S. Tupper
Publikováno v:
American Bar Association Journal, 1949 Sep 01. 35(9), 728-790.
Externí odkaz:
https://www.jstor.org/stable/25716982
Autor:
Xue Song, Marie-Theres Gansauge, Andrew S Tupper, Caroline M S Cauret, Martin Knytl, Ben J. Evans, Matthias Meyer, Benjamin L. S. Furman, Eli Greenbaum
Publikováno v:
Molecular biology and evolution. 37(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b0771ee4aea568f02746041d7f8ba2
https://pubmed.ncbi.nlm.nih.gov/31710681
https://pubmed.ncbi.nlm.nih.gov/31710681
Autor:
Andrew S Tupper, Paul Higgs
Publikováno v:
Journal of Theoretical Biology. 527:110822
It is likely that RNA replication began non-enzymatically, and that polymerases were later selected to speed up the process. We consider replication mechanisms in modern viruses and ask which of these is possible non-enzymatically, using mathematical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9d81681bad9abcb339fe187eb55cd1
https://doi.org/10.1016/j.jtbi.2021.110822
https://doi.org/10.1016/j.jtbi.2021.110822
Autor:
Caroline M S Cauret, Xue-Ying Song, Eli Greenbaum, Martin Knytl, Marie-Theres Gansauge, Andrew S Tupper, Ben J. Evans, Benjamin L. S. Furman, Matthias Meyer
Publikováno v:
Molecular Biology and Evolution
Phenotypic invariance—the outcome of purifying selection—is a hallmark of biological importance. However, invariant phenotypes might be controlled by diverged genetic systems in different species. Here, we explore how an important and invariant p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9b29c7f111a71ae71ff12041693676
https://pubmed.ncbi.nlm.nih.gov/32003798
https://pubmed.ncbi.nlm.nih.gov/32003798
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