Zobrazeno 1 - 10
of 29
pro vyhledávání: '"S. Timothy Motley"'
Autor:
Shane G. Poplawski, Krassimira A. Garbett, Rebekah L. McMahan, Holly B. Kordasiewicz, Hien Zhao, Andrew J. Kennedy, Slavina B. Goleva, Teresa H. Sanders, S. Timothy Motley, Eric E. Swayze, David J. Ecker, J. David Sweatt, Todd P. Michael, Celeste B. Greer
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 19, Iss , Pp 1399-1412 (2020)
Knockout of the memory suppressor gene histone deacetylase 2 (Hdac2) in mice elicits cognitive enhancement, and drugs that block HDAC2 have potential as therapeutics for disorders affecting memory. Currently available HDAC2 catalytic activity inhibit
Externí odkaz:
https://doaj.org/article/663dff1bf29f4ebeac30337a05a1aae1
Autor:
Todd P. Michael, Florian Jupe, Felix Bemm, S. Timothy Motley, Justin P. Sandoval, Christa Lanz, Olivier Loudet, Detlef Weigel, Joseph R. Ecker
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Long-read sequencing technologies facilitate efficient and high quality genome assembly. Here Michael et al. achieve a fast reference assembly for Arabidopsis thaliana KBS-Mac-74 accession using the handheld Oxford Nanopore MinION sequencer and consu
Externí odkaz:
https://doaj.org/article/ad6bc43df0404861ae63cd85f221e0b0
Autor:
Andrew J. Kennedy, Elizabeth J. Rahn, Brynna S. Paulukaitis, Katherine E. Savell, Holly B. Kordasiewicz, Jing Wang, John W. Lewis, Jessica Posey, Sarah K. Strange, Mikael C. Guzman-Karlsson, Scott E. Phillips, Kyle Decker, S. Timothy Motley, Eric E. Swayze, David J. Ecker, Todd P. Michael, Jeremy J. Day, J. David Sweatt
Publikováno v:
Cell Reports, Vol 16, Iss 10, Pp 2666-2685 (2016)
Human haploinsufficiency of the transcription factor Tcf4 leads to a rare autism spectrum disorder called Pitt-Hopkins syndrome (PTHS), which is associated with severe language impairment and development delay. Here, we demonstrate that Tcf4 haploins
Externí odkaz:
https://doaj.org/article/b3ced49ba885434ea78334ce9770d0f4
Autor:
Florian Jupe, Angeline C Rivkin, Todd P Michael, Mark Zander, S Timothy Motley, Justin P Sandoval, R Keith Slotkin, Huaming Chen, Rosa Castanon, Joseph R Nery, Joseph R Ecker
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007819 (2019)
The bacterium Agrobacterium tumefaciens has been the workhorse in plant genome engineering. Customized replacement of native tumor-inducing (Ti) plasmid elements enabled insertion of a sequence of interest called Transfer-DNA (T-DNA) into any plant g
Externí odkaz:
https://doaj.org/article/95ab8fb90c2041d8ab9f191a2f75b785
Autor:
Todd P. Michael, Shane G. Poplawski, S. Timothy Motley, Clemon Dabney, George D. Weiblen, Christopher J. Schwartz, Jonathan P. Wenger, Christopher J. Grassa
Publikováno v:
The New Phytologist
Summary Demand for cannabidiol (CBD), the predominant cannabinoid in hemp (Cannabis sativa), has favored cultivars producing unprecedented quantities of CBD. We investigated the ancestry of a new cultivar and cannabinoid synthase genes in relation to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a38550eca7e754598a5b3d580ff7242
https://doi.org/10.1111/nph.17243
https://doi.org/10.1111/nph.17243
Autor:
Rafael Rivera, Amy Steadman, Crissa Bennett, John T. Connelly, Corrie Ortega, Bernhard H. Weigl, Paras Jain, S. Timothy Motley, Samantha A. Byrnes, Ryan Gallagher
Publikováno v:
Analytical Chemistry
The rapid onset of the global COVID-19 pandemic has led to multiple challenges for accurately diagnosing the infection. One of the main bottlenecks for COVID-19 detection is reagent and material shortages for sample collection, preservation, and puri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868cc238790436f522cab7b7d5ed65d8
http://europepmc.org/articles/PMC7927279
http://europepmc.org/articles/PMC7927279
Autor:
John T. Connelly, Adrienne Chang, Darshana Dadhania, Amy Steadman, Crissa Bennett, Philip Burnham, Omary Mzava, Alexandre Pellan Cheng, Iwijn De Vlaminck, S. Timothy Motley, John R. Lee, Joan Sesing Lenz, Manikkam Suthanthiran
Publikováno v:
Clinical Chemistry
Background Metagenomic sequencing of microbial cell-free DNA (cfDNA) in blood and urine is increasingly used as a tool for unbiased infection screening. The sensitivity of metagenomic cfDNA sequencing assays is determined by the efficiency by which t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25a6cf811bda9c6f018367edda21f931
https://pubmed.ncbi.nlm.nih.gov/34718476
https://pubmed.ncbi.nlm.nih.gov/34718476
Autor:
S. Timothy Motley, Todd P. Michael, Klaus-J. Appenroth, Sarah Gilbert, Phuong N.T. Hoang, Ingo Schubert, Philomena Chu, Eric Lam
Publikováno v:
The Plant Journal. 96:670-684
Duckweeds are the fastest growing angiosperms and have the potential to become a new generation of sustainable crops. Although a seed plant, Spirodela polyrhiza clones rarely flower and multiply mainly through vegetative propagation. Whole-genome seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3ee4e07eb8ef040bed205c1a72d1cc7
https://doi.org/10.1111/tpj.14049
https://doi.org/10.1111/tpj.14049
Autor:
Hien T Zhao, S. Timothy Motley, Teresa H. Sanders, Celeste B. Greer, J. David Sweatt, Krassimira A. Garbett, Shane G. Poplawski, Andrew J. Kennedy, Rebekah L. McMahan, Holly B. Kordasiewicz, Slavina B. Goleva, David J. Ecker, Todd P. Michael, Eric E. Swayze
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 19, Iss, Pp 1399-1412 (2020)
Molecular Therapy. Nucleic Acids
Molecular Therapy. Nucleic Acids
Knockout of the memory suppressor gene histone deacetylase 2 (Hdac2) in mice elicits cognitive enhancement, and drugs that block HDAC2 have potential as therapeutics for disorders affecting memory. Currently available HDAC2 catalytic activity inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0a8147d3d61a64a97bff89ebb62b076
https://pubmed.ncbi.nlm.nih.gov/32160709
https://pubmed.ncbi.nlm.nih.gov/32160709
Autor:
Shane G. Poplawski, Todd P. Michael, Slavina B. Goleva, Andrew J. Kennedy, Krassimira A. Garbett, J. David Sweatt, David J. Ecker, Rebekah L. McMahan, Holly B. Kordasiewicz, Eric E. Swayze, Celeste B. Greer, Hien T Zhao, S. Timothy Motley, Teresa H. Sanders
Repression of the memory suppressor genehistonedeacetylase 2 (Hdac2) in mice elicits cognitive enhancement, and drugs that block HDAC2 catalytic activity are being investigated for treating disorders affecting memory. Currently available compounds th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6521fa9bd81fda0d62e3eaea7aabbca
