Zobrazeno 1 - 10
of 183
pro vyhledávání: '"S. Timmins"'
Autor:
Kamlesh Bhatt, Madhuri Bhagavathula, Sheetal Verma, Graham S. Timmins, Vojo P. Deretic, Jerrold J. Ellner, Padmini Salgame
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 10 (2021)
Tuberculosis (TB) treatment regimens are lengthy, causing non-adherence to treatment. Inadequate treatment can lead to relapse and the development of drug resistance TB. Furthermore, patients often exhibit residual lung damage even after cure, increa
Externí odkaz:
https://doaj.org/article/6d65048b44aa4deea31ae57be740ec92
Autor:
Suresh Kumar, Ruheena Javed, Masroor A. Paddar, Eeva-Liisa Eskelinen, Graham S Timmins, Vojo Deretic
Publikováno v:
Autophagy.
SUMMARYThe precursors to mammalian autophagosomes originate from pre-existing membranes contributed by a number of sources, and subsequently enlarge through intermembrane lipid transfer, then close to sequester the cargo, and merge with lysosomes to
Autor:
Ke Jian Liu, John Weaver, Haikun Zhang, Graham S. Timmins, Song Yu, Xixi Zhou, Rong Pan, Yirong Yang
Publikováno v:
J Cereb Blood Flow Metab
Hemorrhagic stroke is a leading cause of death. The causes of intracerebral hemorrhage (ICH)-induced brain damage are thought to include lysis of red blood cells, hemin release and iron overload. These mechanisms, however, have not proven very amenab
Akademický článek
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Autor:
J. E. P. Connerney, S. Timmins, R. J. Oliversen, J. R. Espley, J. L. Joergensen, S. Kotsiaros, P. S. Joergensen, J. M. G. Merayo, M. Herceg, J. Bloxham, K. M. Moore, A. Mura, A. Moirano, S. J. Bolton, S. M. Levin
Publikováno v:
Connerney, J E P, Timmins, S, Oliversen, R J, Espley, J R, Joergensen, J L, Kotsiaros, S, Joergensen, P S, Merayo, J M G, Herceg, M, Bloxham, J, Moore, K M, Mura, A, Moirano, A, Bolton, S J & Levin, S M 2022, ' A New Model of Jupiter's Magnetic Field at the Completion of Juno's Prime Mission ', Journal of Geophysical Research: Planets, vol. 127, no. 2, e2021JE007055 . https://doi.org/10.1029/2021JE007055
A spherical harmonic model of the magnetic field of Jupiter is obtained from vector magnetic field observations acquired by the Juno spacecraft during 32 of its first 33 polar orbits. These Prime Mission orbits sample Jupiter's magnetic field nearly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76260a2a71c9dc8274659dfd03fa420
https://resolver.caltech.edu/CaltechAUTHORS:20211221-866880000
https://resolver.caltech.edu/CaltechAUTHORS:20211221-866880000
Autor:
Jing Li, Jan Haug Anonsen, Eeva-Liisa Eskelinen, Sigurdur Gudmundsson, Suresh Kumar, Vojo Deretic, Chunyan Ye, Brett S. Phinney, Sandeep Pallikkuth, Keith A. Lidke, Alf Håkon Lystad, Graham S. Timmins, Tor Erik Rusten, Anne Simonsen, Steven B. Bradfute, Michelle Salemi, Ashish Jain, Michal H. Mudd, Aurore Claude-Taupin, Karthikeyan Tangavelou, Ruheena Javed, Lian-Wang Guo
Publikováno v:
Cell
Cell, vol 184, iss 24
Cell, vol 184, iss 24
The biogenesis of mammalian autophagosomes remains to be fully defined. Here, we used cellular and invitro membrane fusion analyses to show that autophagosomes are formed from a hitherto unappreciated hybrid membrane compartment. The autophagic precu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffb491dca442af13c013e56a944b87d4
https://europepmc.org/articles/PMC8616855/
https://europepmc.org/articles/PMC8616855/
Autor:
Etelvino J. H. Bechara, Cleide Costa, Pio Colepicolo, Vadim Viviani, Marcelo P. Barros, Graham S. Timmins, Abner B. Lallf, Walter R. Terra, Clélia Ferreira, Cassius V. Stevani, Moacir A. Torres
Publikováno v:
ARKIVOC, Vol 2007, Iss 8, Pp 311-323 (2007)
Externí odkaz:
https://doaj.org/article/6c569ebb9c50498498f12a8c988d3456
Autor:
S. Timmins, E. Richards, S. Vardoulakis, R. Lucas, Krutika Patel, F. Sanai, Cindy Thamrin, David G. Chapman, B. O'Neill, C. Marsh, D. Figurski, N. Coatsworth
Publikováno v:
TP61. TP061 RESIDENTIAL AND OCCUPATIONAL EXPOSURES: WHERE WE LIVE, WORK, AND BREATHE.
Autor:
Jingyue Jia, Graham S. Timmins, Lukas Brecht, Yuexi Gu, Vojo Deretic, Bhawana Bissa, Lee Allers, Kenneth R. Hallows, Christian Behrends, Seong Won Choi, Mark R. Burge, Mark Zbinden
Publikováno v:
Autophagy
Lysosomal damage activates AMPK, a regulator of macroautophagy/autophagy and metabolism, and elicits a strong ubiquitination response. Here we show that the cytosolic lectin LGALS9 detects lysosomal membrane breach by binding to lumenal glycoepitopes
Autor:
Graham S. Timmins
Publikováno v:
Nature Biotechnology. 37:997-1000
A process for the non-arbitrary determination of obviousness based on examining actual patenting practices of large groups could improve outcomes.