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Autor:
S Thoelen, Geert Leroux-Roels, Guido Moens, Martine Wettendorff, J Dewijngaert, P Jacques, Isabelle Desombere
Publikováno v:
Vaccine. 20:3644-3649
Approximately 5% of vaccinees display an inadequate response after the administration of the standard three dose hepatitis B vaccine. A new hepatitis B vaccine (HBsAg/AS04) formulated with the adjuvant AS04 which contains 3'-deacylated monophosphoryl
Autor:
Gerhard Wiedermann, N. Garcon, F. Ambrosch, C. Thiriart, Moncef Mohamed SmithKline Beecham Bio. s.a Slaoui, Isabelle Desombere, Geert Leroux-Roels, M. Kundi, S Thoelen
Publikováno v:
Vaccine. 18:2095-2101
Although more than 95% of the vaccinated population responds to the currently licensed vaccines against hepatitis B, some groups were found to be low responders. Lipid A as adjuvant, through its ability to activate macrophages, might improve humoral
Publikováno v:
Journal of Travel Medicine. 3:83-90
Background: In recent years, several hepatitis A vaccines have been developed. We wished to evaluate the safety, reactogenicity, and immunogenicity of an inactivated hepatitis A vaccine, containing 1440 EI.U., and to monitor the kinetics of the antib
Publikováno v:
Vaccine. 19(9-10)
Twinrix™ (SmithKline Beecham Biologicals) is a combined hepatitis A and B vaccine licensed with a three-dose schedule. A two-dose combined hepatitis A and B vaccine would facilitate immunisation programs. In this prospective study, 100 healthy adul
Autor:
S, Thoelen
Publikováno v:
Acta gastro-enterologica Belgica. 63(2)
Autor:
A Leentvaar-Kuypers, V Bakasenas, M Bruguera, P. Van Damme, S. Thoelen, Geert Leroux-Roels, Assad Safary, P. C. Frei
Publikováno v:
Vaccine
Hepatitis A and B infections are prevalent world-wide and are a significant cause of morbidity and mortality. A vaccine providing dual protection against hepatitis A and B is now available (Twinrix, SmithKline Beecham Biologicals). Six pivotal vaccin
Publikováno v:
Vaccine
The aim of this study was to evaluate the persistence of antibodies 7 years after hepatitis B booster administration in healthy adult volunteers who were vaccinated in 1987. In October 1986, 188 seronegative, healthy adult volunteers (117 men and 71
Autor:
Isabelle Desombere, Moncef Mohamed Slaoui, S. Thoelen, Pierre Vandepapelière, C. Matheï, Assad Safary, André Meheus, Geert Leroux-Roels, P. Van Damme
Publikováno v:
Vaccine
A formulation of recombinant hepatitis B surface antigen (HBsAg) combined with a novel adjuvant system, SBAS4—a combination of aluminium salt and monophosphoryl lipid A (MPL), was assessed in 27 healthy adult volunteers with a commercial vaccine (E
Publikováno v:
Journal of medical virology
This trial evaluated the reactogenicity, kinetics of antibody induction, and long-term immunogenicity of a 720 enzyme-linked immunosorbent assay units (EL.U.) antigen dose of an inactivated hepatitis A vaccine (Havrix, SmithKline Beecham Biologicals,