Zobrazeno 1 - 10
of 163
pro vyhledávání: '"S. Stoney Simons"'
Autor:
Carson C. Chow, S. Stoney Simons
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Glucocorticoid steroids are among the most prescribed drugs each year. Nonetheless, the many undesirable side effects, and lack of selectivity, restrict their greater usage. Research to increase glucocorticoid specificity has spanned many years. Thes
Externí odkaz:
https://doaj.org/article/5f546db78022499f9e8abcf9cef520f1
Publikováno v:
AIMS Molecular Science, Vol 2, Iss 2, Pp 101-123 (2015)
The different amounts of residual partial agonist activity (PAA) of antisteroids under assorted conditions have long been useful in clinical applications but remain largely unexplained. Not only does a given antagonist often afford unequal induction
Externí odkaz:
https://doaj.org/article/78ad84c6099844899201884edba811e7
Autor:
Zuqin Nie, Chunhua Guo, Subhendu K Das, Carson C Chow, Eric Batchelor, S Stoney Simons Jnr, David Levens
Publikováno v:
eLife, Vol 9 (2020)
Supraphysiological MYC levels are oncogenic. Originally considered a typical transcription factor recruited to E-boxes (CACGTG), another theory posits MYC a global amplifier increasing output at all active promoters. Both models rest on large-scale g
Externí odkaz:
https://doaj.org/article/0acc578d75da4e5c892d7a40c0cd7806
Autor:
Jacob Haqq-Misra, S. Stoney Simons
Publikováno v:
Futures. 106:24-32
The failure to resolve the 70 year old Fermi paradox has been limited by the vastness of the Universe, the inability to search even a fraction of the Universe in a reasonable time period, and the lack of agreement on the criteria for life. We suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64fb2b8f315335caf2741b5050fa88e5
https://doi.org/10.1016/j.futures.2018.06.019
https://doi.org/10.1016/j.futures.2018.06.019
Publikováno v:
In Molecular and Cellular Endocrinology 2008 295(1):59-69
Autor:
Chunhua Guo, David Levens, Carson C. Chow, Zuqin Nie, S Stoney Simons Jnr, Eric Batchelor, Subhendu K. Das
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Supraphysiological MYC levels are oncogenic. Originally considered a typical transcription factor recruited to E-boxes (CACGTG), another theory posits MYC a global amplifier increasing output at all active promoters. Both models rest on large-scale g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830e2325382b7077a18c3f12d95be3b7
http://europepmc.org/articles/PMC7384857
http://europepmc.org/articles/PMC7384857
Autor:
S. Stoney Simons, Carson C. Chow
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Frontiers in Endocrinology
Frontiers in Endocrinology
Glucocorticoid steroids are among the most prescribed drugs each year. Nonetheless, the many undesirable side effects, and lack of selectivity, restrict their greater usage. Research to increase glucocorticoid specificity has spanned many years. Thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92b692b75bf9815be328c045eac7490
http://journal.frontiersin.org/article/10.3389/fendo.2018.00076/full
http://journal.frontiersin.org/article/10.3389/fendo.2018.00076/full
Autor:
S. Stoney Simons
Publikováno v:
Molecular Structure and Biological Activity of Steroids ISBN: 9781351074803
Glucocorticoids evoke many biological responses in the human body. Consequently, pharmacologists have long dreamed of constructing from modular features a steroid with precisely defined and highly specific biological activity. Initially it seemed log
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a40693ee2069f32d4a9b5abb9ecd77c
https://doi.org/10.1201/9781351074803-7
https://doi.org/10.1201/9781351074803-7
Autor:
Geoffrey B. Storchan, S. Stoney Simons, Rong Zhu, Carson C. Chow, Stephen P. Armstrong, Xinping Lu, Madhumita Pradhan
Publikováno v:
Biochemistry
A gene induction competition assay has recently uncovered new inhibitory activities of two transcriptional cofactors, NELF-A and NELF-B, in glucocorticoid-regulated transactivation. NELF-A and -B are also components of the NELF complex, which partici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08eb8244407f4d22f5019b5bcb060a8e
http://europepmc.org/articles/PMC3985961
http://europepmc.org/articles/PMC3985961