Zobrazeno 1 - 10
of 198
pro vyhledávání: '"S. Shoshan"'
Autor:
Michal S. Shoshan
Publikováno v:
CHIMIA, Vol 76, Iss 9 (2022)
It will soon be twenty years since the last chelating agent was clinically approved to be used against toxic metals. Even though metal poisoning has been known to humankind for centuries, only about a dozen compounds, all of which are small molecules
Externí odkaz:
https://doaj.org/article/40f7ff952d8049498fe5895f44e3895f
Autor:
Luca Sauser, Michal S. Shoshan
Publikováno v:
CHIMIA, Vol 75, Iss 6, Pp 530-534 (2021)
More than 50% of proteinogenic amino acid sidechains can bind metal ions, enabling proteins and peptides to bear these ions as cofactors. Nevertheless, post-translational modifications and incorporation of noncanonical amino acids bestow peptides and
Externí odkaz:
https://doaj.org/article/ffec587c8c574b489981ef22fc4d0272
Publikováno v:
ChemMedChem. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21456333f85ec811dc430e77aa3b7fb0
https://doi.org/10.1002/cmdc.202200403
https://doi.org/10.1002/cmdc.202200403
Autor:
Tagwa A. Mohammed, Sheng-Jan Feng, Michal S. Shoshan, Bernhard Spingler, Lubomír Rulíšek, Tadeáš Kalvoda, Luca Sauser
Publikováno v:
Inorganic chemistry. 60(24)
The natural tripeptide glutathione (GSH) is a ubiquitous compound harboring various biological tasks, among them interacting with essential and toxic metal ions. Yet, although weakly binding the poisonous metal lead (Pb), GSH poorly detoxifies it. β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945294eef8068c8b2090dc33a13a7a60
https://pubmed.ncbi.nlm.nih.gov/34860512
https://pubmed.ncbi.nlm.nih.gov/34860512
Autor:
Anna C Jones, Kresta S Antillon, Shannon M Jenkins, Sara N Janos, Heidi N Overton, Dor S Shoshan, Edgar G Fischer, Kristina A Trujillo, Marco Bisoffi
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119314 (2015)
Prostate field cancerization denotes molecular alterations in histologically normal tissues adjacent to tumors. Such alterations include deregulated protein expression, as we have previously shown for the key transcription factor early growth respons
Externí odkaz:
https://doaj.org/article/700822ad8eb147b492580151c2a048af
Autor:
Tagwa A. Mohammed, Christoph M. Meier, Tadeáš Kalvoda, Martina Kalt, Lubomír Rulíšek, Michal S. Shoshan
Publikováno v:
Angewandte Chemie (International ed. in English). 60(22)
Lead (Pb) is a ubiquitous poisonous metal, affecting the health of vast populations worldwide. Medications to treat Pb poisoning suffer from various limitations and are often toxic owing to insufficient metal selectivity. Here, we report a cyclic tet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a324d480a43e67ebffdaf017193c515
https://pubmed.ncbi.nlm.nih.gov/33759306
https://pubmed.ncbi.nlm.nih.gov/33759306
Autor:
Michal S. Shoshan, Luca Sauser
Publikováno v:
Journal of inorganic biochemistry. 212
Among the broad applicability of peptides in numerous aspects of life and technologies, their interactions with lead (Pb), one of the most harmful substances to the environment and health, are constantly explored. So far, peptides were developed for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f1a9a656fbc0a465d19f5add0d2bbd
https://pubmed.ncbi.nlm.nih.gov/32920433
https://pubmed.ncbi.nlm.nih.gov/32920433
Functionalizing noble metal nanoparticles is often necessary to tailor their properties, in particular for biological applications such as drug delivery, therapy and imaging. However, this process is highly challenging, due to the complications in ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb79c2fe12341035fd505201c1f2f975
https://doi.org/10.26434/chemrxiv.9170798.v2
https://doi.org/10.26434/chemrxiv.9170798.v2
Publikováno v:
Angewandte Chemie. International Edition, 58 (15)
Peptide-stabilized platinum nanoparticles (PtNPs) were developed that have significantly greater toxicity against hepatic cancer cells (HepG2) than against other cancer cells and non-cancerous liver cells. The peptide H-Lys-Pro-Gly-dLys-NH2 was ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08ba246f73c0db3845baadfbde24f2b
https://hdl.handle.net/20.500.11850/325266
https://hdl.handle.net/20.500.11850/325266
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