Zobrazeno 1 - 10
of 5 839
pro vyhledávání: '"S. Sands"'
A very nice result of B\'ar\'any and Lehel asserts that every finite subset $X$ or $\mathbb R^d$ can be covered by $f(d)$ $X$-boxes (i.e. each box has two antipodal points in $X$). As shown by Gy\'arf\'as and P\'alv\H{o}lgyi this result would follow
Externí odkaz:
http://arxiv.org/abs/1703.08123
Autor:
Jisu Oh, Amy E. Riek, Kevin T. Bauerle, Adriana Dusso, Kyle P. McNerney, Ruteja A. Barve, Isra Darwech, Jennifer E. Sprague, Clare Moynihan, Rong M. Zhang, Greta Kutz, Ting Wang, Xiaoyun Xing, Daofeng Li, Marguerite Mrad, Nicholas M. Wigge, Esmeralda Castelblanco, Alejandro Collin, Monika Bambouskova, Richard D. Head, Mark S. Sands, Carlos Bernal-Mizrachi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Environmental factors may alter the fetal genome to cause metabolic diseases. It is unknown whether embryonic immune cell programming impacts the risk of type 2 diabetes in later life. We demonstrate that transplantation of fetal hematopoiet
Externí odkaz:
https://doaj.org/article/006bb5f74e894a5ca7b478ca55888534
Autor:
Keigo Takahashi, Elizabeth M. Eultgen, Sophie H. Wang, Nicholas R. Rensing, Hemanth R. Nelvagal, Joshua T. Dearborn, Olivier Danos, Nicholas Buss, Mark S. Sands, Michael Wong, Jonathan D. Cooper
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Although a disease-modifying therapy for classic late infantile neuronal ceroid lipofuscinosis (CLN2 disease) exists, poor understanding of cellular pathophysiology has hampered the development of more effective and persistent therapies. Here, we inv
Externí odkaz:
https://doaj.org/article/5aed6f53cf974a23b8c8e656557757e8
Autor:
Joshua T. Dearborn, Hemanth R. Nelvagal, Nicholas R. Rensing, Keigo Takahashi, Stephanie M. Hughes, Thomas M. Wishart, Jonathan D. Cooper, Michael Wong, Mark S. Sands
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Cannabidiol (CBD) has gained attention as a therapeutic agent and is purported to have immunomodulatory, neuroprotective, and anti-seizure effects. Here, we determined the effects of chronic CBD administration in a mouse model of CLN1 diseas
Externí odkaz:
https://doaj.org/article/350eddea052f435687b37a8c0940ae75
Autor:
Anders F Johnson, Jenna S Sands, Keya M Trivedi, Raedeen Russell, Doris L LaRock, Christopher N LaRock
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1011321 (2023)
Group A Streptococcus (GAS, Streptococcus pyogenes) is a professional human pathogen that commonly infects the skin. Keratinocytes are one of the first cells to contact GAS, and by inducing inflammation, they can initiate the earliest immune response
Externí odkaz:
https://doaj.org/article/3c19c0a6838d4773b02e1508fe20e8cd
Autor:
Hemanth R. Nelvagal, Samantha L. Eaton, Sophie H. Wang, Elizabeth M. Eultgen, Keigo Takahashi, Steven Q. Le, Rachel Nesbitt, Joshua T. Dearborn, Nicholas Siano, Ana C. Puhl, Patricia I. Dickson, Gerard Thompson, Fraser Murdoch, Paul M. Brennan, Mark Gray, Stephen N. Greenhalgh, Peter Tennant, Rachael Gregson, Eddie Clutton, James Nixon, Chris Proudfoot, Stefano Guido, Simon G. Lillico, C. Bruce A. Whitelaw, Jui-Yun Lu, Sandra L. Hofmann, Sean Ekins, Mark S. Sands, Thomas M. Wishart, Jonathan D. Cooper
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 20 (2022)
CLN1 disease, also called infantile neuronal ceroid lipofuscinosis (NCL) or infantile Batten disease, is a fatal neurodegenerative lysosomal storage disorder resulting from mutations in the CLN1 gene encoding the soluble lysosomal enzyme palmitoyl-pr
Externí odkaz:
https://doaj.org/article/fb7adb2cd6174d5a9c38555ece25def7
Autor:
David Gregory
Publikováno v:
Gregory, D J 1999, ' Re-burial of timbers in the marine environment as a means of their long-term storage : experimental studies in Lynæs Sands, Denmark ', International Journal of Nautical Archaeology, vol. 28, no. 4, pp. 343-358 . https://doi.org/10.1016/S1057-2414(98)80006-X
Discussion des resultats d'une experimentation qui met en correlation la deterioration de chene moderne et de toiles ensevelis sous du sable marin avec l'indication des parametres environnementaux de leur etat de preservation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ab4d29b915f739c66ca41c8ec4c368
https://doi.org/10.1016/s1057-2414(98)80006-x
https://doi.org/10.1016/s1057-2414(98)80006-x
Autor:
Michael C. Babcock, Christina R. Mikulka, Bing Wang, Sanjay Chandriani, Sundeep Chandra, Yue Xu, Katherine Webster, Ying Feng, Hemanth R. Nelvagal, Alex Giaramita, Bryan K. Yip, Melanie Lo, Xuntian Jiang, Qi Chao, Josh C. Woloszynek, Yuqiao Shen, Shripad Bhagwat, Mark S. Sands, Brett E. Crawford
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Krabbe disease (KD) and metachromatic leukodystrophy (MLD) are caused by accumulation of the glycolipids galactosylceramide (GalCer) and sulfatide and their toxic metabolites psychosine and lysosulfatide, respectively. We discovered a potent
Externí odkaz:
https://doaj.org/article/b4baa35aa3c440d78cac8c75d11ceb69
Autor:
Rima Rebiai, Emily Rue, Steve Zaldua, Duc Nguyen, Giuseppe Scesa, Martin Jastrzebski, Robert Foster, Bin Wang, Xuntian Jiang, Leon Tai, Scott T. Brady, Richard van Breemen, Maria I. Givogri, Mark S. Sands, Ernesto R. Bongarzone
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Krabbe Disease (KD) is a lysosomal storage disorder characterized by the genetic deficiency of the lysosomal enzyme β-galactosyl-ceramidase (GALC). Deficit or a reduction in the activity of the GALC enzyme has been correlated with the progressive ac
Externí odkaz:
https://doaj.org/article/ebdde43cc35d4f9e87b3d663556551e0