Zobrazeno 1 - 10
of 110
pro vyhledávání: '"S. Samuel Weigt"'
Autor:
Daniel R. Calabrese, Tasha Tsao, Mélia Magnen, Colin Valet, Ying Gao, Beñat Mallavia, Jennifer J. Tian, Emily A. Aminian, Kristin M. Wang, Avishai Shemesh, Elman B. Punzalan, Aartik Sarma, Carolyn S. Calfee, Stephanie A. Christenson, Charles R. Langelier, Steven R. Hays, Jeffrey A. Golden, Lorriana E. Leard, Mary Ellen Kleinhenz, Nicholas A. Kolaitis, Rupal Shah, Aida Venado, Lewis L. Lanier, John R. Greenland, David M. Sayah, Abbas Ardehali, Jasleen Kukreja, S. Samuel Weigt, John A. Belperio, Jonathan P. Singer, Mark R. Looney
Publikováno v:
JCI Insight, Vol 7, Iss 24 (2022)
Clinical outcomes after lung transplantation, a life-saving therapy for patients with end-stage lung diseases, are limited by primary graft dysfunction (PGD). PGD is an early form of acute lung injury with no specific pharmacologic therapies. Here, w
Externí odkaz:
https://doaj.org/article/1ce137fa246e4f4d9647ad53ba99ced1
Autor:
Jiurong Liang, Guanling Huang, Xue Liu, Forough Taghavifar, Ningshan Liu, Yizhou Wang, Nan Deng, Changfu Yao, Ting Xie, Vrishika Kulur, Kristy Dai, Ankita Burman, Simon C. Rowan, S. Samuel Weigt, John Belperio, Barry Stripp, William C. Parks, Dianhua Jiang, Paul W. Noble
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 11 (2022)
Type 2 alveolar epithelial cells (AEC2s) function as progenitor cells in the lung. We have shown previously that failure of AEC2 regeneration results in progressive lung fibrosis in mice and is a cardinal feature of idiopathic pulmonary fibrosis (IPF
Externí odkaz:
https://doaj.org/article/f7539cbaaa2b4928beaa1bce4118eb7f
Autor:
Anna-Maria Hoffmann-Vold, S. Samuel Weigt, Rajan Saggar, Vyacheslav Palchevskiy, Elizabeth R. Volkmann, Lloyd L. Liang, David Ross, Abbas Ardehali, Joseph P. Lynch, III, John A. Belperio
Publikováno v:
EBioMedicine, Vol 50, Iss , Pp 379-386 (2019)
Background: Some interstitial lung disease (ILD) patients develop a progressive fibrosing-ILD phenotype (PF-ILD), with similar persistent lung function decline suggesting common molecular pathways involved. Nintedanib, a tyrosine kinase inhibitor tar
Externí odkaz:
https://doaj.org/article/acead5a69b63476e8d773a006e546600
Autor:
Xue Liu, Simon C. Rowan, Jiurong Liang, Changfu Yao, Guanling Huang, Nan Deng, Ting Xie, Di Wu, Yizhou Wang, Ankita Burman, Tanyalak Parimon, Zea Borok, Peter Chen, William C. Parks, Cory M. Hogaboam, S. Samuel Weigt, John Belperio, Barry R. Stripp, Paul W. Noble, Dianhua Jiang
Publikováno v:
iScience, Vol 24, Iss 6, Pp 102551- (2021)
Summary: Pulmonary mesenchymal cells are critical players in both the mouse and human during lung development and disease states. They are increasingly recognized as highly heterogeneous, but there is no consensus on subpopulations or discriminative
Externí odkaz:
https://doaj.org/article/61fae4523109433c93b49fa80896a3e0
Autor:
David Sayah, MD, PhD, S. Samuel Weigt, MD, Allison Ramsey, MD, Abbas Ardehali, MD, Jeff Golden, MD, David J. Ross, MD
Publikováno v:
Transplantation Direct, Vol 6, Iss 10, p e608 (2020)
Background. Telehealth platforms with remote phlebotomy and biomarker implementation represent a novel paradigm for surveillance after lung transplantation (LT). In a pilot study, we investigated donor-derived cell-free DNA (dd-cfDNA) in plasma using
Externí odkaz:
https://doaj.org/article/d05df9ec271b40ca83d08bbe61c50eb5
Autor:
David W. Dai, MD, Bryan Garber, MD, S. Samuel Weigt, MD, Scott Worswick, MD, Bernard M. Kubak, MD, PhD, Joseph P. Lynch, 3rd, MD, Michael Y. Shino, MD, Ariss DerHovanessian, MD, Rajan Saggar, MD, David J. Ross, MD, David M. Sayah, MD, PhD
Publikováno v:
Transplantation Direct, Vol 3, Iss 12, p e333 (2017)
Externí odkaz:
https://doaj.org/article/3f0f198dcdab4e8cbfb639d6f2231bd8
Autor:
S Samuel Weigt, Xiaoyan Wang, Vyacheslav Palchevskiy, Aric L Gregson, Naman Patel, Ariss DerHovanessian, Michael Y Shino, David M Sayah, Shirin Birjandi, Joseph P Lynch, Rajan Saggar, Abbas Ardehali, David J Ross, Scott M Palmer, David Elashoff, John A Belperio
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169894 (2017)
BACKGROUND:Chronic Lung Allograft Dysfunction (CLAD) is the main limitation to long-term survival after lung transplantation. Although CLAD is usually not responsive to treatment, earlier identification may improve treatment prospects. METHODS:In a n
Externí odkaz:
https://doaj.org/article/51c2cfff00ed41e99d5e67da95b3a38c
Autor:
Michael Y Shino, S Samuel Weigt, Ning Li, Vyacheslav Palchevskiy, Ariss Derhovanessian, Rajan Saggar, David M Sayah, Richard H Huynh, Aric L Gregson, Michael C Fishbein, Abbas Ardehali, David J Ross, Joseph P Lynch, Robert M Elashoff, John A Belperio
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0180281 (2017)
Since the pathogenesis of chronic lung allograft dysfunction (CLAD) remains poorly defined with no known effective therapies, the identification and study of key events which increase CLAD risk is a critical step towards improving outcomes. We hypoth
Externí odkaz:
https://doaj.org/article/f26eb751205e4bdab74fb06f6ebd3e38
Autor:
Paul W. Noble, Guanling Huang, Harmik J. Soukiasian, Dianhua Jiang, Xiangrong Guan, Apoorva Mulay, Gregory David, S. Samuel Weigt, Tanyalak Parimon, Barry R. Stripp, John A. Belperio, Gianni Carraro, Xue Liu, Peter Chen, Changfu Yao
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 203:707-717
Rationale: Idiopathic pulmonary fibrosis (IPF) is an insidious and fatal interstitial lung disease associated with declining pulmonary function. Accelerated aging, loss of epithelial progenitor cell function and/or numbers, and cellular senescence ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95648ec87af82c68b1b223d8ab7c4252
https://doi.org/10.1164/rccm.202004-1274oc
https://doi.org/10.1164/rccm.202004-1274oc
Autor:
Tereza Martinu, Angela Koutsokera, Christian Benden, Edward Cantu, Daniel Chambers, Marcelo Cypel, Jeffrey Edelman, Amir Emtiazjoo, Andrew J. Fisher, John R. Greenland, Don Hayes, David Hwang, Brian C. Keller, Erika D. Lease, Michael Perch, Masaaki Sato, Jamie L. Todd, Stijn Verleden, Jan von der Thüsen, S. Samuel Weigt, Shaf Keshavjee, Cecilia Chaparro, David Wilson Roe, Frank D'Ovidio, George Chaux, Greg Snell, Laurent Godinas, Mohamed Al-Aloul, Steven Hays, Jamie Todd, Amy Rigby, Louis Clauden, Matthew Morrell, Puneet Garcha, Sanjeev Raman, Soma Jyothula, Michael Trotter, Erika Lease, Cassie Kennedy, Chadi A Hage, Saima Aslam, Shahid Husain, Katharina Wassilew, Reinaldo Rampolla-Selles, Siddhartha G Kapnadak, Umesh Goswami, John Greenland, Aric Gregson, Bart Vanaudenaerde, Tji Gan, Brian Keller, Laura K Frye, Margaret Hannan, Harish Seethamraju, Rade Tomic, Remzi Bag, Alicia Mitchell, Jorge Mallea, Maria Crespo, Sangeeta Bhorade, Cantu Edward, Cypel Marcelo, Gundeep Dhillon, Jason Christie, Jessica GY Luc, Keith M Wille, Olufemi Akindipe, Omar Mohamedaly, Christopher Wigfield, Ernestina Melicoff-Portillo, Marc Schecter, Shailendra Das, Ani Orchanian-Cheff, George Tomlinson
Publikováno v:
Journal of Heart and Lung Transplantation, 39(11), 1171-1190. Elsevier Inc.
The Journal of heart and lung transplantation, vol. 39, no. 11, pp. 1171-1190
The Journal of Heart and Lung Transplantation
Journal of heart and lung transplantation
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, vol 39, iss 11
The Journal of heart and lung transplantation, vol. 39, no. 11, pp. 1171-1190
The Journal of Heart and Lung Transplantation
Journal of heart and lung transplantation
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, vol 39, iss 11
Bronchoalveolar lavage (BAL) is a key clinical and research tool in lung transplantation (LTx). However, BAL collection and processing are not standardized across LTx centers. This International Society for Heart and Lung Transplantation-supported co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9bd086fe638872b461917e9b8180904
https://doi.org/10.1016/j.healun.2020.07.006
https://doi.org/10.1016/j.healun.2020.07.006