Zobrazeno 1 - 10
of 77
pro vyhledávání: '"S. Sabedot"'
Autor:
Grayson A. Herrgott, James M. Snyder, Ruicong She, Tathiane M. Malta, Thais S. Sabedot, Ian Y. Lee, Jacob Pawloski, Guilherme G. Podolsky-Gondim, Karam P. Asmaro, Jiaqi Zhang, Cara E. Cannella, Kevin Nelson, Bartow Thomas, Ana C. deCarvalho, Laura A. Hasselbach, Kelly M. Tundo, Rehnuma Newaz, Andrea Transou, Natalia Morosini, Victor Francisco, Laila M. Poisson, Dhananjay Chitale, Abir Mukherjee, Maritza S. Mosella, Adam M. Robin, Tobias Walbert, Mark Rosenblum, Tom Mikkelsen, Steven Kalkanis, Daniela P. C. Tirapelli, Daniel J. Weisenberger, Carlos G. Carlotti, Jack Rock, Ana Valeria Castro, Houtan Noushmehr
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Recurrence of meningiomas is unpredictable by current invasive methods based on surgically removed specimens. Identification of patients likely to recur using noninvasive approaches could inform treatment strategy, whether intervention or mo
Externí odkaz:
https://doaj.org/article/d702b94546f74016b63743f1d7fefc6e
Autor:
Camila Ferreira de Souza, Thais S. Sabedot, Tathiane M. Malta, Lindsay Stetson, Olena Morozova, Artem Sokolov, Peter W. Laird, Maciej Wiznerowicz, Antonio Iavarone, James Snyder, Ana deCarvalho, Zachary Sanborn, Kerrie L. McDonald, William A. Friedman, Daniela Tirapelli, Laila Poisson, Tom Mikkelsen, Carlos G. Carlotti, Jr., Steven Kalkanis, Jean Zenklusen, Sofie R. Salama, Jill S. Barnholtz-Sloan, Houtan Noushmehr
Publikováno v:
Cell Reports, Vol 23, Iss 2, Pp 637-651 (2018)
Summary: Glioma diagnosis is based on histomorphology and grading; however, such classification does not have predictive clinical outcome after glioblastomas have developed. To date, no bona fide biomarkers that significantly translate into a surviva
Externí odkaz:
https://doaj.org/article/706cab09ad454b2da0b587fe71e18729
Autor:
Grayson A Herrgott, Karam P Asmaro, Michael Wells, Thais S Sabedot, Tathiane M Malta, Maritza S Mosella, Kevin Nelson, Lisa Scarpace, Jill S Barnholtz-Sloan, Andrew E Sloan, Warren R Selman, Ana C deCarvalho, Laila M Poisson, Abir Mukherjee, Adam M Robin, Ian Y Lee, James Snyder, Tobias Walbert, Mark Rosenblum, Tom Mikkelsen, Arti Bhan, John Craig, Steven Kalkanis, Jack Rock, Houtan Noushmehr, Ana Valeria Castro
Publikováno v:
Neuro-Oncology. 24:1126-1139
Background DNA methylation abnormalities are pervasive in pituitary neuroendocrine tumors (PitNETs). The feasibility to detect methylome alterations in circulating cell-free DNA (cfDNA) has been reported for several central nervous system (CNS) tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35424c8cddc7421b6e9620f44ee1f9cf
https://doi.org/10.1093/neuonc/noac050
https://doi.org/10.1093/neuonc/noac050
Autor:
Wilfred F. J. van IJcken, Marc Sanson, Thais S. Sabedot, C Mircea S Tesileanu, Roberta Rudà, Thierry Gorlia, Olivier Chinot, Iris de Heer, Leland Rogers, Kenneth Aldape, Alba A. Brandes, Walter Taal, Kin Jip Cheung, Anna K. Nowak, Robert B. Jenkins, Michael A. Vogelbaum, Vassilis Golfinopoulos, Pim J. French, Wolfgang Wick, Myra van Linde, Hendrikus J. Dubbink, Johan M. Kros, M. Weller, Matthew E. Griffin, Rutger W W Brouwer, Brigitta G. Baumert, Sanjeev Gill, Houtan Noushmehr, Paul Clement, Catherine McBain, Helen Wheeler, Jean Francois Baurain, Pieter Wesseling, Sara Erridge, Youri Hoogstrate, Warren P. Mason, Andreas von Deimling, Martin J. van den Bent
Publikováno v:
Neuro-Oncology
Neuro-Oncology, Oxford University Press (OUP), 2021, 23 (9), pp.1547-1559. ⟨10.1093/neuonc/noab088⟩
Neuro-Oncology, 23(9), 1547-1559. Oxford University Press
Neuro-oncology, Vol. xx, no.xx, p. xx (2021)
Neuro-Oncology, 2021, 23 (9), pp.1547-1559. ⟨10.1093/neuonc/noab088⟩
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Neuro-oncology, 23(9), 1547-1559. Oxford University Press
Neuro-Oncology, Oxford University Press (OUP), 2021, 23 (9), pp.1547-1559. ⟨10.1093/neuonc/noab088⟩
Neuro-Oncology, 23(9), 1547-1559. Oxford University Press
Neuro-oncology, Vol. xx, no.xx, p. xx (2021)
Neuro-Oncology, 2021, 23 (9), pp.1547-1559. ⟨10.1093/neuonc/noab088⟩
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Neuro-oncology, 23(9), 1547-1559. Oxford University Press
Background Survival in patients with IDH1/2-mutant (mt) anaplastic astrocytomas is highly variable. We have used the prospective phase 3 CATNON trial to identify molecular factors related to outcome in IDH1/2mt anaplastic astrocytoma patients. Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e028f0c3a1383a4e27bee5fc95e42b
http://europepmc.org/articles/PMC8408862
http://europepmc.org/articles/PMC8408862
Autor:
Frederick S. Varn, Kevin C. Johnson, Jan Martinek, Jason T. Huse, MacLean P. Nasrallah, Pieter Wesseling, Lee A.D. Cooper, Tathiane M. Malta, Taylor E. Wade, Thais S. Sabedot, Daniel Brat, Peter V. Gould, Adelheid Wöehrer, Kenneth Aldape, Azzam Ismail, Santhosh K. Sivajothi, Floris P. Barthel, Hoon Kim, Emre Kocakavuk, Nazia Ahmed, Kieron White, Indrani Datta, Hyo-Eun Moon, Steven Pollock, Christine Goldfarb, Ga-Hyun Lee, Luciano Garofano, Kevin J. Anderson, Djamel Nehar-Belaid, Jill S. Barnholtz-Sloan, Spyridon Bakas, Annette T. Byrne, Fulvio D’Angelo, Hui K. Gan, Mustafa Khasraw, Simona Migliozzi, D. Ryan Ormond, Sun Ha Paek, Erwin G. Van Meir, Annemiek M.E. Walenkamp, Colin Watts, Tobias Weiss, Michael Weller, Karolina Palucka, Lucy F. Stead, Laila M. Poisson, Houtan Noushmehr, Antonio Iavarone, Roel G.W. Verhaak, Kristin D. Alfaro, Samirkumar B. Amin, David M. Ashley, Christoph Bock, Andrew Brodbelt, Ketan R. Bulsara, Ana Valeria Castro, Jennifer M. Connelly, Joseph F. Costello, John F. de Groot, Gaetano Finocchiaro, Pim J. French, Anna Golebiewska, Ann C. Hau, Chibo Hong, Craig Horbinski, Kasthuri S. Kannan, Mathilde CM. Kouwenhoven, Anna Lasorella, Peter S. LaViolette, Keith L. Ligon, Allison K. Lowman, Shwetal Mehta, Hrvoje Miletic, Annette M. Molinaro, Ho Keung Ng, Simone P. Niclou, Johanna M. Niers, Joanna J. Phillips, Raul Rabadan, Ganesh Rao, Guido Reifenberger, Nader Sanai, Susan C. Short, Peter Sillevis Smitt, Andrew E. Sloan, Marion Smits, James M. Snyder, Hiromichi Suzuki, Ghazaleh Tabatabai, Georgette Tanner, William H. Tomaszewski, Michael Wells, Bart A. Westerman, Helen Wheeler, Jichun Xie, W.K. Alfred Yung, Gelareh Zadeh, Junfei Zhao, Roel GW. Verhaak
Publikováno v:
Cell, 185(12), 2184-2199.e16. Cell Press
Cell
Cell, vol 185, iss 12
The GLASS Consortium 2022, ' Glioma progression is shaped by genetic evolution and microenvironment interactions ', Cell, vol. 185, no. 12, pp. 2184-2199.e16 . https://doi.org/10.1016/j.cell.2022.04.038
Cell, 185(12), 2184-2199.e16. CELL PRESS
Cell
Cell, vol 185, iss 12
The GLASS Consortium 2022, ' Glioma progression is shaped by genetic evolution and microenvironment interactions ', Cell, vol. 185, no. 12, pp. 2184-2199.e16 . https://doi.org/10.1016/j.cell.2022.04.038
Cell, 185(12), 2184-2199.e16. CELL PRESS
The factors driving therapy resistance in diffuse glioma remain poorly understood. To identify treatment-associated cellular and genetic changes, we analyzed RNA and/or DNA sequencing data from the temporally separated tumor pairs of 304 adult patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36aa8231290284197e37208bfab4dbba
https://research.vumc.nl/en/publications/312bbb0a-1328-4405-bfbe-cce4f07b8a67
https://research.vumc.nl/en/publications/312bbb0a-1328-4405-bfbe-cce4f07b8a67
Autor:
Lucy F. Stead, Mustafa Khasraw, Michael Weller, Frederick S. Varn, Nazia Ahmed, Annemiek M E Walenkamp, Houtan Noushmehr, Erwin G. Van Meir, Tathiane M. Malta, Luciano Garofano, Jason T. Huse, David Ormond, Colin Watts, Pieter Wesseling, Thais S. Sabedot, Emre Kocakavuk, Floris P. Barthel, Taylor Wade, Roel G.W. Verhaak, Spyridon Bakas, Jill S. Barnholtz-Sloan, Sun Ha Paek, Kevin M. Johnson, Tobias Weiss, Hui K Gan, Simona Migliozzi, Fulvio D'Angelo, Indrani Datta, Laila M. Poisson, Antonio Iavarone, Hoon Kim
Publikováno v:
Neuro Oncol
Diffuse glioma is characterized by a poor prognosis and a universal resistance to therapy, though the evolutionary processes behind this resistance remain unclear. The Glioma Longitudinal Analysis (GLASS) Consortium has previously demonstrated that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a991e1416956193b224da692e3847b8
https://europepmc.org/articles/PMC8598702/
https://europepmc.org/articles/PMC8598702/
Autor:
Thais S. Sabedot, Richard A. Young, Alba Font-Tello, Marcos A. S. Fonseca, Jessica Reddy, Brian J. Abraham, Beth Y. Karlan, Matthew L. Freedman, Heidi Chang, Daniele Chaves-Moreira, Bogdan Pasaniuc, Ji-Heui Seo, Robbin Nameki, Ronny Drapkin, Simon A. Gayther, Isaac A. Klein, Alexander Gusev, De-Chen Lin, Ursula A. Matulonis, Forough Abbasi, Tathiane M. Malta, Houtan Noushmehr, Lena K. Afeyan, Felipe Segato Dezem, Rosario I. Corona, Norma Rodriguez-Malave, Xianzhi Lin, Kate Lawrenson, Henry W. Long, Paloma Cejas
Publikováno v:
Science Advances
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Science advances, vol 7, iss 48
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Science advances, vol 7, iss 48
Description
The CaCTS algorithm nominates cancer cell master transcription factors and guides a model of ovarian cancer regulatory circuitry.
Critical developmental “master transcription factors” (MTFs) can be subverted during tumorigen
The CaCTS algorithm nominates cancer cell master transcription factors and guides a model of ovarian cancer regulatory circuitry.
Critical developmental “master transcription factors” (MTFs) can be subverted during tumorigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09b96658538afba37b87e761bdfd98e
http://europepmc.org/articles/PMC8612691
http://europepmc.org/articles/PMC8612691
Autor:
Bart A. Westerman, Bauke Ylstra, Peter A. E. Sillevis Smitt, Guido Reifenberger, Lucy F. Stead, Fulvio D'Angelo, Ann-Christin Hau, Frederick S. Varn, Sun Ha Paek, Johanna M. Niers, Indrani Datta, D. Ryan Ormond, Antonio Iavarone, Pieter Wesseling, Anna Lasorella, Kenneth Aldape, Michael Weller, Emre Kocakavuk, Laila M. Poisson, Spyridon Bakas, Annemiek M E Walenkamp, Tathiane M. Malta, Wies Vallentgoed, Houtan Noushmehr, Simona Migliozzi, Pim J. French, Mathilde C.M. Kouwenhoven, Hui K Gan, Martin J. van den Bent, Kevin C. Johnson, Erwin G. Van Meir, Tobias Weiss, Marion Smits, Luciano Garofano, Jill S. Barnholtz-Sloan, Mohammad Hasanain, Roel G.W. Verhaak, Mustafa Khasraw, Simone P. Niclou, Thais S. Sabedot
SummaryTumor adaptation or selection is thought to underlie therapy resistance of gliomas. To investigate the longitudinal epigenetic evolution of gliomas in response to therapeutic pressure, we performed an epigenomic analysis of 143 matched initial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bc7b1fac81c575aa14e78b9cdab1c08
https://doi.org/10.1101/2021.08.09.455687
https://doi.org/10.1101/2021.08.09.455687
Autor:
Mark L. Rosenblum, Tathiane M. Malta, Ian Yu Lee, James Snyder, Ana C. deCarvalho, Thais S. Sabedot, Laila M. Poisson, Houtan Noushmehr, Abir Mukherjee, Anavaleria Castro, Adam M. Robin, Tom Mikkelsen, Steven N. Kalkanis, Dhananjay Chitale, Michael Wells, Jack Rock, Tobias Walbert, Karam Asmaro
Publikováno v:
Neurosurgery. 66:310-630
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dc1405cee78fa0de559750e9effdbeb
https://doi.org/10.1093/neuros/nyz310_630
https://doi.org/10.1093/neuros/nyz310_630
Publikováno v:
Neuro-Oncology. 24:ii91-ii91
Background Adult diffuse glioma is a heterogenous brain tumor group that has malignant potential and recurring properties. Glioma CpG island methylator phenotype (G-CIMP) associated with chromatin remodeling encompasses two different methylation degr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::123a47cd44e9c56a9d7726e9e112a61d
https://doi.org/10.1093/neuonc/noac174.320
https://doi.org/10.1093/neuonc/noac174.320