Zobrazeno 1 - 10
of 58
pro vyhledávání: '"S. S. Zail"'
Publikováno v:
Scandinavian Journal of Haematology. 14:81-85
The administration of vitamin E, a natural antioxidant, to a patient with paroxysmal nocturnal haemoglobinuria (PNH) failed to diminish the urinary excretion of 59-Fe as monitored by 59-Fe whole body counting and urinary loss of isotope. However, in
Publikováno v:
British medical journal. 3(5562)
Publikováno v:
Blood. 92(7)
Autor:
S S Zail, T L Coetzer
Publikováno v:
Journal of Clinical Investigation. 74:753-762
The interaction of spectrin with spectrin-depleted inside-out membrane vesicles was studied in a kindred with an atypical variant of hereditary elliptocytosis inherited in a recessive manner. The probands are characterized by prominent elliptocytosis
Autor:
S. S. Zail, Stephen Lambert
Publikováno v:
Blood. 69:473-478
A kindred is described in which two brothers with a poikilocytic variant of hereditary elliptocytosis (HE) were found to have a defect of spectrin dimer association and a decreased spectrin-band 3 ratio. Two-dimensional gel electrophoresis of limited
Publikováno v:
Blood. 72:1926-1929
Genomic DNA from five kindreds and two individuals with hereditary elliptocytosis [HE(4.1+)] and a partial deficiency of protein 4.1 [HE(4.1+)] was extracted and probed with a cDNA for protein 4.1. When using a fragment of the cDNA that encompassed t
Autor:
Theresa L. Coetzer, S. S. Zail
Publikováno v:
Blood. 59:900-905
The proportion of spectrin tetramers and dimers in 4 degrees C low ionic strength extracts of red cell membranes of 9 subjects with 4 different variants of hereditary elliptocytosis (HE) and 2 subjects with hereditary spherocytosis (HS) was determine
Autor:
S. S. Zail, Theresa L. Coetzer
Publikováno v:
Blood. 56:159-167
G6PD-deficient red cells (nonhemolytic variants) incubated for 24 hr in medium containing glucose maintain their adenosine triphosphate (ATP) levels but show a pronounced fall in reduced glutathione (GSH) levels. Membranes of such ATP-replete, GSH-de
Publikováno v:
British Journal of Haematology. 18:79-88
Summary. The combination of iron overload and hexachlorobenzene (HCB) feeding in rats produces an ‘experimental symptomatic porphyria’. Studies of hepatic haem biosynthesis in this model showed a decrease in total liver haem and cytochromes P450
Autor:
S. M. Joubert, S. S. Zail
Publikováno v:
British Journal of Haematology. 15:123-130
Hepatic ALA synthetase activity was determined on biopsy material from 12 patients with symptomatic porphyria. Five patients had values at least 1.5 times greater than the highest normal value whilst the remaining seven had values within or slightly