Zobrazeno 1 - 10
of 133
pro vyhledávání: '"S. S. Terekhov"'
Autor:
R. S. Kalinin, V. O. Shipunova, Y. P. Rubtsov, V. M. Ukrainskay, A. Schulga, E. V. Konovalova, D. V. Volkov, I. A. Yaroshevich, A. M. Moysenovich, A. A. Belogurov, G. B. Telegin, A. S. Chernov, M. A. Maschan, S. S. Terekhov, V. D. Knorre, E. Khurs, N. V. Gnuchev, A. G. Gabibov, S. M. Deyev
Publikováno v:
Doklady Biochemistry and Biophysics. 508:17-20
Abstract The development of CAR-T specific therapy made a revolution in modern oncology. Despite the pronounced therapeutic effects, this novel approach displayed several crucial limitations caused by the complications in pharmacokinetics and pharmac
Autor:
S. S. Terekhov, V. P. Nespriadko
Publikováno v:
Art of Medicine. :176-180
Gingival retraction is the procedure of bending the gingival margin away from the tooth surface, which provides sufficient horizontal and vertical space between the prepared finish line and the gingiva for the introduction of a sufficient amount of i
Autor:
Nikolay E. Nifantiev, Anton P. Tyurin, Alexander S. Shashkov, Andrey V. Mardanov, Evgeny N. Nikolaev, S. S. Terekhov, Valeriya V. Kulyaeva, Eugene A. Rogozhin, Genrikh S. Katrukha, Alexey A. Chistov, Alexander S. Apt, Elena G. Gladkikh, Natalia E. Grammatikova, Ilya A. Osterman, Alexander Zherebker, Konstantin B. Majorov, Nikolai V. Ravin, Olga S. Ostroumova, Zakhar O. Shenkarev, Tatyana V. Kravchenko, Alexander S. Paramonov, Maxim V. Shuvalov, Vladimir A. Brylev, Milita V Kocharovskaya, Dmitry S. Tsvetkov, Elena P. Mirchink, Vladimir A. Korshun, Anna A. Baranova, A. V. Beletsky, Elena B. Isakova, Vera A. Alferova, Olga A. Dontsova, Olda A. Lapchinskaya, Elena V. Svirshchevskaya, Igor A. Prokhorenko, Svetlana S. Efimova, Igor Ivanov, Mikhail V. Biryukov, Gulnara K. Kudryakova
Publikováno v:
Angewandte Chemie International Edition. 60:18694-18703
We report a novel family of natural lipoglycopeptides produced by Streptomyces sp. INA-Ac-5812. Two major components of the mixture, named gausemycins A and B, were isolated, and their structures were elucidated. The compounds are cyclic peptides wit
Autor:
S. S. Terekhov, Allan Tsung, Han Wang, Jiayi He, Casey A. Maguire, Alexey Stepanov, George Tetz, Dmitry Genkin, Victor Tetz, Yujia Xia, Hai Huang, Hongji Zhang, Yu Wang, Amblessed E. Onuma, V. M. Ukrainskaya
Publikováno v:
Molecular Oncology, Vol 14, Iss 11, Pp 2920-2935 (2020)
Molecular Oncology
Molecular Oncology
Liver metastasis is a major cause of colorectal cancer‐related death. Although DNase I displays antimetastatic activity by inhibition of NETs, its clinical use is limited due to its short biologic half‐life. AAV‐mediated gene expression of DNas
Autor:
N. N. Kostin, A. A. Kudryaeva, S. S. Terekhov, M. N. Zakharova, Alexander G. Gabibov, Alexey A. Belogurov, M. V. Ivanova, Ya. A. Lomakin, Alena N. Kaminskaya, T. O. Simaniv
Publikováno v:
Bulletin of Experimental Biology and Medicine. 167:329-334
Previous data showed that myelin-reactive autoantibodies found in patients with multiple sclerosis and mice with experimental autoimmune encephalomyelitis recognize and hydrolyze various fragments of myelin basic protein (MBP). Moreover, antibody-med
Autor:
Marina A. Zenkova, Alexey Stepanov, Igor A. Yaroshevich, Dmitry V. Bagrov, Jia Xie, Oleg V. Markov, A.I. Sokolova, R. S. Kalinin, Sergey M. Deyev, V. M. Ukrainskaya, Victoria O. Shipunova, Elena Kulakovskaya, Michael Maschan, Dmitry Pershin, Richard A. Lerner, N.A. Podoplelova, Eugene G. Maksimov, Y.P. Rubtsov, A. G. Gabibov, S. S. Terekhov, Anastasiya L. Oshchepkova
Development of CAR-T therapy led to immediate success in the treatment of B cell leukemia and lymphoma. It also raised an opportunity to design new protocols to target solid tumors. Manufacturing of therapy-competent functional CAR-T cells needs robu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eebffd5358b85892f8cfc4d00bb7776e
https://doi.org/10.1101/2021.03.18.435976
https://doi.org/10.1101/2021.03.18.435976
Autor:
Alexander S. Shashkov, Elena P. Mirchink, Olga S. Ostroumova, Valeriya V. Kulyaeva, Mikhail V. Biryukov, Genrikh S. Katrukha, Dmitry S. Tsvetkov, Andrey V. Mardanov, Vera A. Alferova, Anna A. Baranova, Evgeny N. Nikolaev, Nikolai V. Ravin, Tatyana V. Kravchenko, Alexander S. Apt, Alexey A. Chistov, Natalia E. Grammatikova, Vladimir A. Brylev, Elena B. Isakova, Ilya A. Osterman, Maxim V. Shuvalov, Anton P. Tyurin, S. S. Terekhov, Gulnara K. Kudryakova, A. V. Beletsky, Vladimir A. Korshun, Olda A. Lapchinskaya, Eugene A. Rogozhin, Nikolay E. Nifantiev, Milita V Kocharovskaya, Olga A. Dontsova, Alexander Zherebker, Igor A. Prokhorenko, Svetlana S. Efimova, Igor Ivanov, Elena G. Gladkikh, Konstantin B. Majorov, Zakhar O. Shenkarev, Alexander S. Paramonov, Elena V. Svirshchevskaya
We report a novel family of natural lipoglycopeptides produced by Streptomyces sp. INA-Ac-5812. Two major components of the mixture, named gausemycins A and B, were isolated, and their structures were elucidated. The compounds are cyclic peptides wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78a43b108fcec0119e71dce12b198cf2
https://doi.org/10.26434/chemrxiv.13012814.v1
https://doi.org/10.26434/chemrxiv.13012814.v1
Publikováno v:
Acta Naturae. 10:23-29
The increasing number of infections caused by antibiotic-resistant strains of pathogens challenges modern technologies of drug discovery. Combinatorial chemistry approaches are based on chemical libraries. They enable the creation of high-affinity lo
Publikováno v:
Bulletin of experimental biology and medicine. 169(3)
We optimized a method for the preparation and purification of self-assembled protein nanocontainers EPN, the latest achievement in protein engineering. These nanocontainers are highly stable and provide the possibility of highly specific loading of a
Autor:
Jia Xie, Hongkai Zhang, Igor A. Yaroshevich, Oleg Markov, Elena Kulakovskaya, Marina A. Zenkova, Eugene G. Maksimov, Anstasiia Sokolova, Victoria O. Shipunova, Rustam Ziganshin, Dmitry V. Bagrov, Anastasiya L. Oshchepkova, V. M. Ukrainskaya, Sergey M. Deyev, S. S. Terekhov, Alexey Stepanov, A. S. Chernov, Alexander G. Gabibov, Georgii B. Telegin, Yuri Rubtsov, Nadezhda Podoplelova, Michael Maschan, Richard A. Lerner, Dmitry Pershin
Publikováno v:
Small. 17:2102643
Development of CAR-T therapy led to immediate success in the treatment of B cell leukemia. Manufacturing of therapy-competent functional CAR-T cells needs robust protocols for ex vivo/in vitro expansion of modified T-cells. This step is challenging,