Zobrazeno 1 - 10
of 25
pro vyhledávání: '"S. Rieffel"'
Publikováno v:
MethodsX, Vol 1, Iss C, Pp 155-161 (2014)
Growing insect cells with high air space in culture vessel is common from the early development of suspension cell culture. We believed and followed it with the hope that it allows sufficient air for optimal cell growth. However, we missed to identif
Externí odkaz:
https://doaj.org/article/d96633f4b0f24d7c924276f0360f8567
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Mark Freeman, Victoria Head, Binesh Shrestha, Michael Faller, Elizabeth Hardaker, Mark R Dowling, Rene Hemmig, Lucy Elphick, Johan C. Hill, Darren Le Grand, David D. Pascoe, Florence Zink, Christopher Thomson, Andrew Lister, S. Rieffel, David Beattie, Oliver Ross Steward
Publikováno v:
Bioorganicmedicinal chemistry letters. 31
A series of inhibitors of Autotaxin (ATX) have been developed from a high throughput screening hit, 1a, which shows an alternative binding mode to known catalytic site inhibitors. Selectivity over the hERG channel and microsomal clearance were depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e384195e054e5c4b466872e8c04973
https://pubmed.ncbi.nlm.nih.gov/33160025
https://pubmed.ncbi.nlm.nih.gov/33160025
Publikováno v:
MethodsX
Graphical abstract
Baculovirus (BV) mediated insect cell expression system utilizes transfection as a first step to introduce recombinant baculovirus DNA into insect cells. Many labs are still relying on the conventional liposome based transfect
Baculovirus (BV) mediated insect cell expression system utilizes transfection as a first step to introduce recombinant baculovirus DNA into insect cells. Many labs are still relying on the conventional liposome based transfect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eca4d23819f38c3eb73c3cc1bd93438
http://europepmc.org/articles/PMC4872675
http://europepmc.org/articles/PMC4872675
Autor:
Aurélie Winterhalter, Sharadha Subramanian, Tiffany Tsang, Jean-Michel Florent, Stephen F. Hardy, Laura Tandeske, Armin Widmer, Arndt Meyer, Johanna M. Jansen, Charles Wartchow, S. Rieffel, Stephania Widger, Yumin Dai, Tatiana Zavorotinskaya, Savithri Ramurthy, Dove Jeffrey H, Yun Feng, Julia Klopp, Isabel Zaror, Kenneth Crawford, Alvar D. Gossert, Susan Fong, Darrin Stuart, Yuji Mishina, John Fuller, Gwynn Pardee, Andreas Lingel, Lenahan William P, Keith B. Pfister, Mohammad Hekmat-Nejad, Jamie Narberes, Eric Fang, Dirksen E. Bussiere, Sylvia Ma, Wolfgang Jahnke, Jan Marie Cheng, Chrystèle Henry
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174706 (2017)
PLoS ONE, 12 (4)
PLoS ONE
PLoS ONE, 12 (4)
PLoS ONE
RAS mutations lead to a constitutively active oncogenic protein that signals through multiple effector pathways. In this chemical biology study, we describe a novel coupled biochemical assay that measures activation of the effector BRAF by prenylated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74adeb6145df8376b86b98aae0c5870
http://europepmc.org/articles/PMC5383040?pdf=render
http://europepmc.org/articles/PMC5383040?pdf=render
Autor:
Niko Schmiedeberg, Gabriele Fendrich, Ralf Glatthar, Henrik Möbitz, André Strauss, Sascha Gutmann, Silvio Ofner, Peter Drückes, Sylvie Antz, Aleksandar Stojanovic, Helmut Sparrer, S. Rieffel, Henri Mattes, Alexandra Hinniger, Troxler Thomas J
Publikováno v:
The Journal of biological chemistry. 290(24)
Macrophages are important cellular effectors in innate immune responses and play a major role in autoimmune diseases such as rheumatoid arthritis. Cancer Osaka thyroid (COT) kinase, also known as mitogen-activated protein kinase kinase kinase 8 (MAP3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b3e5b0ee5576c7802d57675ce481965
https://pubmed.ncbi.nlm.nih.gov/25918157
https://pubmed.ncbi.nlm.nih.gov/25918157
Autor:
Alvar D. Gossert, Dove Jeffrey H, Sharadha Subramanian, Susan Fong, Bill Lenahan, Gwynn Pardee, Simona Gokhin, Andreas Lingel, Arndt Meyer, Savithri Ramurthy, Laura Tandeske, David Farley, Charles Wartchow, Tatiana Zavorotinskaya, Julia Klopp, John Fuller, Kevin Shoemaker, Eric Fang, Anke Blechschmidt, Yumin Dai, Chrystèle Henry, Isabel Zaror, Dirksen E. Bussiere, Wolfgang Jahnke, Jean-Michel Florent, C. Gregory Paris, Keith B. Pfister, Mohammad Hekmat-Nejad, Jamie Narberes, Johanna M. Jansen, Stephen F. Hardy, Armin Widmer, Stephania Widger, Tiffany Tsang, Paul A. Renhowe, S. Rieffel
Publikováno v:
Molecular Cancer Research. 12:B38-B38
Mutated forms of KRAS are no longer able to switch effectors between “on” and “off” states. It is known that the function of KRAS is controlled by key parts in the C-terminus, including six consecutive lysines, a terminal prenyl moiety and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3da1dadaf490935832bd212e91663a65
https://doi.org/10.1158/1557-3125.rasonc14-b38
https://doi.org/10.1158/1557-3125.rasonc14-b38
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Francis Bitsch, M. Kroemer, Rene Hemmig, E. Bourgier, J.-M. Rondeau, Wolfgang Jahnke, S. Lehmann, Martin Geiser, André Strauss, S. Rieffel, J.R. Green, Paul Ramage
Publikováno v:
Acta Crystallographica Section A Foundations of Crystallography. 63:s119-s119
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c35b49770cadf4f8ceac7468d93df7b
https://doi.org/10.1107/s0108767307097449
https://doi.org/10.1107/s0108767307097449
Autor:
Paul Ramage, André Strauss, M. Kroemer, Francis Bitsch, E. Bourgier, S. Rieffel, J.R. Green, J.-M. Rondeau, Martin Geiser, Wolfgang Jahnke, S. Lehmann, Rene Hemmig
Publikováno v:
Bone. 38:61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d126f1adb0096a1f0ea0b6a9936267fd
https://doi.org/10.1016/j.bone.2005.12.069
https://doi.org/10.1016/j.bone.2005.12.069