Zobrazeno 1 - 5
of 5
pro vyhledávání: '"S. Randall Frame"'
Autor:
Julia S. Kimbell, David R. Plowchalk, Ramesh Sarangapani, Matthew S. Bogdanffy, S. Randall Frame
Publikováno v:
Toxicological Sciences. 46:235-246
Physiologically based pharmacokinetic (PBPK) models require estimates of catalytic rate constants controlling the metabolism of xenobiotics. Usually, these constants are derived from whole tissue homogenates wherein cellular architecture and enzyme c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::973310a4bd247b1f0a4e5ebc1a455368
https://doi.org/10.1093/toxsci/46.2.235
https://doi.org/10.1093/toxsci/46.2.235
Publikováno v:
Inhalation Toxicology. 9:331-350
Inhalation exposure of rats to 600 ppm vinyl acetate monomer produced nasal papillomas, squamous-cell carcinomas, and carcinoma in situ in rats. These tumors had a very long latency to onset, appearing only at terminal sacrifice. Nonneoplastic lesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3550c6e49fd740116a47e2366a011d7
https://doi.org/10.1080/089583797198178
https://doi.org/10.1080/089583797198178
Publikováno v:
Fundamental and Applied Toxicology. 26:223-238
The purpose of this study was to assess the oncogenic potential of vinyl fluoride in rats and mice when administered by inhalation. Male and female rats and mice were exposed to 0, 25, 250, or 2500 ppm vinyl fluoride 6 hr per day, 5 days per week, fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c2c630791f31150aea023fd655a636
https://doi.org/10.1006/faat.1995.1093
https://doi.org/10.1006/faat.1995.1093
Publikováno v:
Inhalation toxicology. 16(9)
Dimethyl sulfate (DMS) is an alkylating agent that is carcinogenic to the respiratory tract of rodents. DNA adducts, cell proliferation, and histopathology were assessed in rats to better understand the molecular dosimetry and tissue dynamics associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72dc0810c57ab74af5fa76879c92dc4e
https://pubmed.ncbi.nlm.nih.gov/16036751
https://pubmed.ncbi.nlm.nih.gov/16036751
Publikováno v:
Inhalation Toxicology; 1997, Vol. 9 Issue 4, p331-350, 20p