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Akademický článek

Development and validation of a digital biopsy model to predict microvascular invasion in hepatocellular carcinoma

Autor: Emrullah Birgin, Heiner Nebelung, Schaima Abdelhadi, Johann S. Rink, Matthias F. Froelich, Svetlana Hetjens, Mohammad Rahbari, Patrick Téoule, Erik Rasbach, Christoph Reissfelder, Jürgen Weitz, Stefan O. Schoenberg, Carina Riediger, Verena Plodeck, Nuh N. Rahbari

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

BackgroundMicrovascular invasion is a major histopathological risk factor of postoperative recurrence in patients with hepatocellular carcinoma. This study aimed to develop and validate a digital biopsy model using imaging features to predict microva

Externí odkaz: https://doaj.org/article/ff8a3baac1264690aac9013790299f0f

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Nanoparticle Targeting in Chemo‐Resistant Ovarian Cancer Reveals Dual Axis of Therapeutic Vulnerability Involving Cholesterol Uptake and Cell Redox Balance

Autor: Yinu Wang, Andrea E. Calvert, Horacio Cardenas, Jonathon S. Rink, Dominik Nahotko, Wenan Qiang, C. Estelle Ndukwe, Fukai Chen, Russell Keathley, Yaqi Zhang, Ji‐Xin Cheng, C. Shad Thaxton, Daniela Matei

Publikováno v: Advanced Science, Vol 11, Iss 13, Pp n/a-n/a (2024)

Abstract Platinum (Pt)‐based chemotherapy is the main treatment for ovarian cancer (OC); however, most patients develop Pt resistance (Pt‐R). This work shows that Pt‐R OC cells increase intracellular cholesterol through uptake via the HDL recep

Externí odkaz: https://doaj.org/article/c74208f5f91d408dacb341f964db8aef

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Akademický článek

Establishing an MSU service in a medium-sized German urban area—clinical and economic considerations

Autor: Johann S. Rink, Fabian Tollens, Andrej Tschalzev, Christian Bartelt, Armin Heinzl, Jens Hoffmann, Stefan O. Schoenberg, Annika Marzina, Vesile Sandikci, Carla Wiegand, Carolin Hoyer, Kristina Szabo

Publikováno v: Frontiers in Neurology, Vol 15 (2024)

Background and purposeMobile stroke units (MSU) have been demonstrated to improve prehospital stroke care in metropolitan and rural regions. Due to geographical, social and structural idiosyncrasies of the German city of Mannheim, concepts of establi

Externí odkaz: https://doaj.org/article/47d0897ff0314d38bdd9b9048bcdc253

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Akademický článek

Virtual Non-Contrast versus True Native in Photon-Counting CT: Stability of Density of Upper Abdominal Organs and Vessels

Autor: Florian Haag, Shanice S. Emmrich, Alexander Hertel, Johann S. Rink, Dominik Nörenberg, Stefan O. Schoenberg, Matthias F. Froelich

Publikováno v: Diagnostics, Vol 14, Iss 11, p 1130 (2024)

The clinical use of photon-counting CT (PCCT) allows for the generation of virtual non-contrast (VNC) series from contrast-enhanced images. In routine clinical practice, specific issues such as ruling out acute bleeding require non-contrast images. T

Externí odkaz: https://doaj.org/article/a7fc9f0794f8482097e4072ebdeba257

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Akademický článek

Automated Screening for Abdominal Aortic Aneurysm in CT Scans under Clinical Conditions Using Deep Learning

Autor: Alena-K. Golla, Christian Tönnes, Tom Russ, Dominik F. Bauer, Matthias F. Froelich, Steffen J. Diehl, Stefan O. Schoenberg, Michael Keese, Lothar R. Schad, Frank G. Zöllner, Johann S. Rink

Publikováno v: Diagnostics, Vol 11, Iss 11, p 2131 (2021)

Abdominal aortic aneurysms (AAA) may remain clinically silent until they enlarge and patients present with a potentially lethal rupture. This necessitates early detection and elective treatment. The goal of this study was to develop an easy-to-train

Externí odkaz: https://doaj.org/article/03bf2908103447d88829b25b0ecaa4b7

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Akademický článek

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Akademický článek

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Dynamic Contrast-Enhanced MR Imaging Evaluation of Perfusional Changes and Ablation Zone Size after Combination Embolization and Ablation Therapy

Autor: Jason Chiang, Hiro Sparks, Johann S. Rink, M. Franca Meloni, Frank Hao, Kyung H. Sung, Edward W. Lee

Publikováno v: Journal of vascular and interventional radiology : JVIR.

The objectives of this study were to assess the utility of dynamic contrast-enhanced magnetic resonance (MR) imaging in quantifying parenchymal perfusional changes after embolization and to characterize the association between pharmacokinetic (PK) pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7429052cf843d9f7e9af26db889f0d2
https://pubmed.ncbi.nlm.nih.gov/36368517

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Prostatic Artery Embolization for Treatment of Lower Urinary Tract Symptoms: A Markov Model-Based Cost-Effectiveness Analysis

Autor: Johann S. Rink, Matthias F. Froelich, Justin P. McWilliams, Christian Gratzke, Thomas Huber, Eva Gresser, Stefan O. Schoenberg, Steffen J. Diehl, Dominik Nörenberg

Publikováno v: Journal of the American College of Radiology : JACR. 19(6)

The aim of this study was to investigate whether prostatic artery embolization (PAE) can be considered a long-term cost-effective treatment option in patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia in comparison t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786503849e164ed2a4681104335c529d
https://pubmed.ncbi.nlm.nih.gov/35550882

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