Zobrazeno 1 - 10
of 14
pro vyhledávání: '"S. R. Whittemore"'
Autor:
M. J. Eaton Ph.D., J. A. Plunkett, M. A. Martinez, T. Lopez, S. Karmally, P. Cejas, S. R. Whittemore
Publikováno v:
Cell Transplantation, Vol 8 (1999)
The use of cell lines utilized as biologic “minipumps” to provide antinociceptive molecules, such as GABA, in animal models of pain is a newly developing area in transplantation biology. The neuronal cell line, RN33B, derived from E13 brain stem
Externí odkaz:
https://doaj.org/article/7fa31ccba99641d49777a2d92c09e87d
Publikováno v:
Pain. 72:59-69
The RN46A cell line was derived from embryonic day 13 rat medullary raphe cells by infection with a retrovirus encoding the temperature-sensitive mutant of SV40 large T antigen. This cell line is neuronally restricted and constitutively differentiate
Publikováno v:
Journal of Neurocytology. 25:101-111
RN33B, a conditionally-immortalized neuronal cell line, survives and differentiates following grafting into the neocortex and hippocampus of adult and neonatal rat hosts. We have previously shown that these cells assume shapes characteristic of endog
Publikováno v:
Pharmacopsychiatry. 34
We have investigated biochemical mechanisms that may underlie the antidepressant effects of Hypericum LI 160. We found that LI 160 inhibits uptake of serotonin and norepinephrine in cultures of rat cortical astrocytes. Observed differences in the kin
Autor:
S R, Whittemore, S M, Onifer
Publikováno v:
Progress in brain research. 127
Publikováno v:
Journal of human virology. 3(4)
To study the effect of cell differentiation on the vulnerability of human neural cell types to human cytomegalovirus (HCMV) infection.Primary cultures of human fetal neuroepithelial stem cells and differentiating neuroepithelial precursor cells were
Autor:
H B, Rind, S R, Whittemore
Publikováno v:
Journal of neuroscience research. 56(2)
These studies examined the extent to which protein kinase C (PKC) and cAMP-dependent protein kinase (PKA) regulate the neuronal differentiation of the raphe-derived neuronal cell line, RN33B. A differentiation-specific 2.25-fold increase in soluble P
Publikováno v:
Journal of neuroscience research. 57(5)
In the presence of epidermal growth factor (EGF) and/or fibroblast growth factor 2 (FGF2), neuroepithelial precursor cells from dissociated fetal human spinal cord are mitotically active and form free-floating spheres of undifferentiated cells. Proli
Publikováno v:
Cell transplantation. 8(1)
The use of cell lines utilized as biologic "minipumps" to provide antinociceptive molecules, such as GABA, in animal models of pain is a newly developing area in transplantation biology. The neuronal cell line, RN33B, derived from E13 brain stem raph
Publikováno v:
Journal of neuroscience research. 52(2)
We have previously demonstrated an augmentation of serotonergic activity within various brain areas following infusion of brain-derived neurotrophic factor (BDNF) into the midbrain near the periaqueductal gray and dorsal and median raphe nuclei (PAG/