Zobrazeno 1 - 10
of 10
pro vyhledávání: '"S. R. McKercher"'
Publikováno v:
Molecular and Cellular Biology. 12:368-378
PU.1 is a B-cell- and macrophage-specific transcription factor. By an electrophoretic mobility shift assay and dimethyl sulfate methylation interference assays, we show that PU.1 binds to DNA sequences within the immunoglobulin kappa 3' enhancer (kap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f800211568da85e18349ba9c11e08d5
https://doi.org/10.1128/mcb.12.1.368-378.1992
https://doi.org/10.1128/mcb.12.1.368-378.1992
Autor:
Michael L. Atchison, M. J. Klemsz, Sujatha Nagulapalli, S. R. Mckercher, R. A. Maki, Jm. R. Pongubala
Publikováno v:
Molecular and Cellular Biology. 12:368-378
PU.1 is a B-cell- and macrophage-specific transcription factor. By an electrophoretic mobility shift assay and dimethyl sulfate methylation interference assays, we show that PU.1 binds to DNA sequences within the immunoglobulin kappa 3' enhancer (kap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::870a0b3d8456435e687e6ce34400a117
https://doi.org/10.1128/mcb.12.1.368
https://doi.org/10.1128/mcb.12.1.368
Autor:
Jeanne F. Loring, Stephen Yip, S. R. McKercher, Evan Y. Snyder, Franz-Josef Mueller, Samia J. Khoury, Jaime Imitola
Publikováno v:
Opportunities and Challenges of the Therapies Targeting CNS Regeneration ISBN: 9783540240822
Neural stem and progenitor cells express a variety of receptors that enable them to sense and react to signals emanating from physiological and pathophysiological conditions in the brain as well as elsewhere in the body. Many of these receptors and w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe6dcd5bcce73c9fb70ccc9dfeed8e12
https://doi.org/10.1007/3-540-27626-2_6
https://doi.org/10.1007/3-540-27626-2_6
Publikováno v:
Ernst Schering Research Foundation workshop. (53)
Neural stem and progenitor cells express a variety of receptors that enable them to sense and react to signals emanating from physiological and pathophysiological conditions in the brain as well as elsewhere in the body. Many of these receptors and w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37a161ca9f42b94469a9d2a122cba3df
https://pubmed.ncbi.nlm.nih.gov/16315610
https://pubmed.ncbi.nlm.nih.gov/16315610
Autor:
A M, Lichanska, C M, Browne, G W, Henkel, K M, Murphy, M C, Ostrowski, S R, McKercher, R A, Maki, D A, Hume
Publikováno v:
Blood. 94(1)
During mouse embryogenesis, macrophage-like cells arise first in the yolk sac and are produced subsequently in the liver. The onset of liver hematopoiesis is associated with the transition from primitive to definitive erythrocyte production. This rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6153510dee9f18c3aaee6af54677e036
https://pubmed.ncbi.nlm.nih.gov/10381505
https://pubmed.ncbi.nlm.nih.gov/10381505
Publikováno v:
Blood. 93(9)
Mice homozygous for the disruption of the PU.1 (Spi-1) gene do not produce mature macrophages. In determining the role of PU.1 in macrophage differentiation, the present study investigated whether or not there was commitment to the monocytic lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6f2285de926ec5c6141c3cc8ae0e0f1
https://pubmed.ncbi.nlm.nih.gov/10216079
https://pubmed.ncbi.nlm.nih.gov/10216079
Publikováno v:
Blood. 91(10)
The ets family transcription factor PU.1 is expressed in monocytes/macrophages, neutrophils, mast cells, B cells, and early erythroblasts, but not in T cells. We have recently shown that PU.1 gene disruption results in mice with no detectable monocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::31c60aa6fbd5b321fc9174cebe82d6f7
https://pubmed.ncbi.nlm.nih.gov/9573007
https://pubmed.ncbi.nlm.nih.gov/9573007
Autor:
S R, McKercher, B E, Torbett, K L, Anderson, G W, Henkel, D J, Vestal, H, Baribault, M, Klemsz, A J, Feeney, G E, Wu, C J, Paige, R A, Maki
Publikováno v:
The EMBO journal. 15(20)
PU.1 is a member of the ets family of transcription factors and is expressed exclusively in cells of the hematopoietic lineage. Mice homozygous for a disruption in the PU.1 DNA binding domain are born alive but die of severe septicemia within 48 h. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::367c53f90bcba7ecc4a95c167c66db4a
https://pubmed.ncbi.nlm.nih.gov/8896458
https://pubmed.ncbi.nlm.nih.gov/8896458
Publikováno v:
Blood. 88(8)
Transcription factors play an important role choreographing lineage commitment and expansion of blood cells. Nuclear factors that are expressed primarily or exclusively in hematopoietic cells are likely candidates for regulating blood cell developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d58313213986a38052880615b68d6c7e
https://pubmed.ncbi.nlm.nih.gov/8874188
https://pubmed.ncbi.nlm.nih.gov/8874188
Autor:
S. R. McKercher, G. Jahangiri, C. G. Putney, E. J. Mathur, Manouchehr M. Shahbaz, Charles E. Grimshaw
Publikováno v:
Biochemistry. 28(13)
Aldose reductase, purified to homogeneity from bovine kidney, is converted in a temperature-dependent process from a low-Km/low-Vmax form to a high-Km/high-Vmax form of the enzyme. Activation, which results in significant changes in the protein secon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84dd5dbeb30cb5ded25057e76fbe37c0
https://pubmed.ncbi.nlm.nih.gov/2550052
https://pubmed.ncbi.nlm.nih.gov/2550052