Zobrazeno 1 - 10
of 16
pro vyhledávání: '"S. R. Lentz"'
Autor:
S. R. Lentz, M. Cerqueira, D. Janic, C. Kempton, I. Matytsina, M. Misgav, J. Oldenburg, M. Ozelo, M. Recht, A. Rosholm, A. Savic, T. Suzuki, A. Tiede, E. Santagostino
Publikováno v:
Haemophilia. 22:e445-e449
Autor:
R. N. Rodionov, S. R. Lentz
Publikováno v:
"Arterial’naya Gipertenziya" ("Arterial Hypertension"). 14:110-115
Resume Hyperhomocysteinemia is hypothesized to be a cardiovascular risk factor. Severe hyperhomocysteinemia due to rare genetic impairments of homocysteine metabolism predisposes to atherothrombosis. Even partial correction of homocysteine levels in
Autor:
M, Ozelo, M, Misgav, F, Abdul Karim, S R, Lentz, M, Martin-Salces, I, Matytsina, T, Saugstrup, E, Santagostino
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 21(5)
Autor:
S R, Lentz, J E, Sadler
Publikováno v:
Blood. 81:683-689
Intracellular protein transport in endothelial cells is selectively inhibited by homocysteine, a thiol amino acid associated with both thrombosis and atherosclerosis. In a previous study, homocysteine decreased cell surface expression of the surface
Publikováno v:
Clinical science (London, England : 1979). 100(2)
Hyperhomocyst(e)inaemia is associated with endothelial dysfunction in animals and humans. Mechanisms responsible for endothelial dysfunction in hyperhomocyst(e)inaemia are poorly understood, but may involve impaired bioavailability of endothelium-der
Publikováno v:
Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 46(4)
Thrombomodulin is a cell-surface glycoprotein that regulates coagulation and fibrinolysis. Expression of thrombomodulin by epidermal keratinocytes is tightly regulated during squamous differentiation and cutaneous wound healing.To determine the conse
Publikováno v:
Blood. 90(5)
The proteolytically activated thrombin receptor (TR) is expressed by T lymphocytes, which suggests that thrombin may modulate T-cell activation at sites of hemostatic stress. We examined the relationship between TR function and T-cell activation in t
Publikováno v:
Blood. 89(3)
Publikováno v:
Blood. 88(6)
Thrombomodulin is a cell-surface anticoagulant glycoprotein expressed by vascular endothelial cells and epidermal keratinocytes. Thrombomodulin expression in endothelial cells is regulated by retinoic acid and tumor necrosis factor-alpha (TNF), agent
Publikováno v:
The Journal of biological chemistry. 268(20)
Activation of protein C by thrombin is stimulated by the endothelial cell cofactor thrombomodulin. The structural regions of thrombomodulin necessary for cofactor activity have been localized to the fourth through sixth epidermal growth factor (EGF)-