Zobrazeno 1 - 10
of 132
pro vyhledávání: '"S. Pienaar"'
Autor:
Amica C. Müller-Nedebock, Abigail L. Pfaff, Ilse S. Pienaar, Sulev Kõks, Francois H. van der Westhuizen, Joanna L. Elson, Soraya Bardien
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Mitochondrial DNA (mtDNA), a potential source of mitochondrial dysfunction, has been implicated in Parkinson’s disease (PD). However, many previous studies investigating associations between mtDNA population variation and PD reported inconsistent o
Externí odkaz:
https://doaj.org/article/f877b442e8d1404ab7be17ae21b008da
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Several mitochondrial DNA (mtDNA) haplogroup association studies have suggested that common mtDNA variants are associated with multifactorial diseases, including Alzheimer’s disease (AD). However, such studies have also produced conflicting results
Externí odkaz:
https://doaj.org/article/abdc5486ee694025871befa58f2ebe8a
Autor:
Jacques S. Pienaar, Carl C. Theron
Publikováno v:
African Journal of Psychological Assessment, Vol 3, Iss 0, Pp e1-e13 (2021)
This article deals with the need for the conceptualisation and operationalisation of a modern graduate leader performance construct and the development and psychometric evaluation of a (graduate) leader competency questionnaire. The need for an inves
Externí odkaz:
https://doaj.org/article/5e2eef1aa6bb441eaf06679475222170
Autor:
Belinda Fouché, Stephanie Turner, Rebecca Gorham, Eloise J. Stephenson, Simon Gutbier, Joanna L. Elson, Olimpo García-Beltrán, Francois H. Van Der Westhuizen, Ilse S. Pienaar
Publikováno v:
Molecular Neurobiology. 60:749-767
Coumarins are plant-derived polyphenolic compounds belonging to the benzopyrones family, possessing wide-ranging pharmaceutical applications including cytoprotection, which may translate into therapeutic potential for multiple diseases, including Par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0776a13573b661bbdf5b2332aee79bb8
https://doi.org/10.1007/s12035-022-03107-8
https://doi.org/10.1007/s12035-022-03107-8
Autor:
Ilse S. Pienaar, Cecilia Heyne Lee, Joanna L. Elson, Louisa McGuinness, Stephen M. Gentleman, Raj N. Kalaria, David T. Dexter
Publikováno v:
Neurobiology of Disease, Vol 74, Iss , Pp 392-405 (2015)
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become an accepted treatment for motor symptoms in a subset of Parkinson's disease (PD) patients. The mechanisms why DBS is effective are incompletely understood, but previous studies
Externí odkaz:
https://doaj.org/article/86cbc8150e8048b786c474f66ca51211
Autor:
Frank W, Lewis, Kathleen, Bird, Jean-Philippe, Navarro, Rawa, El Fallah, Jeremy, Brandel, Véronique, Hubscher-Bruder, Andrew, Tsatsanis, James A, Duce, David, Tétard, Samuel, Bourne, Mahmoud, Maina, Ilse S, Pienaar
Publikováno v:
Dalton transactions (Cambridge, England : 2003). 51(9)
Iron dysregulation, dopamine depletion, cellular oxidative stress and α-synuclein protein mis-folding are key neuronal pathological features seen in the progression of Parkinson's disease. Iron chelators endowed with one or more therapeutic modes of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ca24ea8a13b9756a8f9991eeb5ee661a
https://pubmed.ncbi.nlm.nih.gov/35147617
https://pubmed.ncbi.nlm.nih.gov/35147617
Publikováno v:
PeerJ, Vol 3, p e1175 (2015)
Parkinson’s disease (PD) is an age-associated neurodegenerative disorder hallmarked by a loss of mesencephalic dopaminergic neurons. Accurate recapitulation of the PD movement phenotype in animal models of the disease is critical for understanding
Externí odkaz:
https://doaj.org/article/1d17592447f24402a7c59873253c5aad
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2277
In light of accumulating evidence suggestive of cell type-specific vulnerabilities as a result of normal aging processes that adversely affect the brain, as well as age-related neurodegenerative disorders such as Parkinson's disease (PD), the current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::169a9d5fb80438a038a36b1be2185f00
https://pubmed.ncbi.nlm.nih.gov/34080159
https://pubmed.ncbi.nlm.nih.gov/34080159
Publikováno v:
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 111(8)
Background. The COVID-19 pandemic and responses by governments, including lockdowns, have had various consequences for lives and livelihoods. South Africa (SA) was one of the countries that implemented severely restrictive lockdowns to reduce transmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c8bdd48ce0e0f11133986a704508fc
https://pubmed.ncbi.nlm.nih.gov/35227349
https://pubmed.ncbi.nlm.nih.gov/35227349
Publikováno v:
Methods in Molecular Biology ISBN: 9781071612699
In light of accumulating evidence suggestive of cell type-specific vulnerabilities as a result of normal aging processes that adversely affect the brain, as well as age-related neurodegenerative disorders such as Parkinson's disease (PD), the current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c552e19d07eecb71b72b8eedab3760f9
https://doi.org/10.1007/978-1-0716-1270-5_19
https://doi.org/10.1007/978-1-0716-1270-5_19
