Zobrazeno 1 - 10
of 574
pro vyhledávání: '"S. Penman"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
In England, SARS-CoV-2 vaccines were initially targeted to older, more vulnerable people; first vaccine doses were prioritised over second doses, and an interval of twelve weeks was used between doses. Here, the authors assess the impacts of these po
Externí odkaz:
https://doaj.org/article/95a8daae0b314c5085c7de362ab021cb
Autor:
Viola Introini, Alejandro Marin-Menendez, Guilherme Nettesheim, Yen-Chun Lin, Silvia N. Kariuki, Adrian L. Smith, Letitia Jean, John N. Brewin, David C. Rees, Pietro Cicuta, Julian C. Rayner, Bridget S. Penman
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Malaria parasites such as Plasmodium falciparum have exerted formidable selective pressures on the human genome. Of the human genetic variants associated with malaria protection, beta thalassaemia (a haemoglobinopathy) was the earliest to be
Externí odkaz:
https://doaj.org/article/e6afa95052a148bb94000f442cc19fc0
Autor:
Rodrigo Barquera, Joaquin Zuniga, José Flores-Rivera, Teresa Corona, Bridget S. Penman, Diana Iraíz Hernández-Zaragoza, Manuel Soler, Letisia Jonapá-Gómez, Kalyan C. Mallempati, Petra Yescas, Adriana Ochoa-Morales, Konstantinos Barsakis, José Artemio Aguilar-Vázquez, Maricela García-Lechuga, Michael Mindrinos, María Yunis, Luis Jiménez-Alvarez, Lourdes Mena-Hernández, Esteban Ortega, Alfredo Cruz-Lagunas, Víctor Hugo Tovar-Méndez, Julio Granados, Marcelo Fernández-Viña, Edmond Yunis
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-22 (2020)
Abstract Here we studied HLA blocks and haplotypes in a group of 218 Lacandon Maya Native American using a high-resolution next generation sequencing (NGS) method. We assessed the genetic diversity of HLA class I and class II in this population, and
Externí odkaz:
https://doaj.org/article/82c8f093dc154ddc8cdaf23e543b5c4c
Autor:
Bridget S Penman, Sylvain Gandon
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 10, p e1008181 (2020)
The mutation responsible for Duffy negativity, which impedes Plasmodium vivax infection, has reached high frequencies in certain human populations. Conversely, mutations capable of blocking the more lethal P. falciparum have not succeeded in malariou
Externí odkaz:
https://doaj.org/article/abe0a2f25fc54dd6be35bdb43812ce51
Autor:
Radu Tusco, Anne-Claire Jacomin, Ashish Jain, Bridget S. Penman, Kenneth Bowitz Larsen, Terje Johansen, Ioannis P. Nezis
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Selective autophagy describes the selective degradation of cellular components upon stress or nutrient deficiency, but whether it modulates innate immunity is unclear. Here the authors show that Drosophila Kenny may be an evolution-selected autophagy
Externí odkaz:
https://doaj.org/article/81ed953ad9ea48a8980dd1e3764b1e04
Autor:
Carinna Hockham, Supachai Ekwattanakit, Samir Bhatt, Bridget S Penman, Sunetra Gupta, Vip Viprakasit, Frédéric B Piel
Publikováno v:
eLife, Vol 8 (2019)
Severe forms of α-thalassaemia, haemoglobin H disease and haemoglobin Bart’s hydrops fetalis, are an important public health concern in Southeast Asia. Yet information on the prevalence, genetic diversity and health burden of α-thalassaemia in th
Externí odkaz:
https://doaj.org/article/145f9cf736854f4595b477c34180f22e
Akademický článek
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Autor:
Maricela García-Lechuga, Manuel Soler, Diana Iraíz Hernández-Zaragoza, Marcelo Fernandez-Vina, Michael N. Mindrinos, Víctor Hugo Tovar-Méndez, Bridget S. Penman, Kalyan C. Mallempati, Lourdes Mena-Hernández, Alfredo Cruz-Lagunas, Teresa Corona, Joaquín Zúñiga, Petra Yescas, María Yunis, Konstantinos Barsakis, José Flores-Rivera, Esteban Ortega, Luis Jiménez-Alvarez, Julio Granados, Adriana Ochoa-Morales, José Artemio Aguilar-Vázquez, Edmond J. Yunis, Rodrigo Barquera, Letisia Jonapá-Gómez
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-22 (2020)
Scientific Reports
Scientific Reports
Here we studied HLA blocks and haplotypes in a group of 218 Lacandon Maya Native American using a high-resolution next generation sequencing (NGS) method. We assessed the genetic diversity of HLA class I and class II in this population, and determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744ce955d1062552e927b551bbddecb0
http://link.springer.com/article/10.1038/s41598-020-58897-5
http://link.springer.com/article/10.1038/s41598-020-58897-5
Autor:
Eleanor R Watkins, Bridget S Penman, José Lourenço, Caroline O Buckee, Martin C J Maiden, Sunetra Gupta
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1005034 (2015)
The bacterial pathogen, Streptococcus pneumoniae (the pneumococcus), is a leading cause of life-threatening illness and death worldwide. Available conjugate vaccines target only a small subset (up to 13) of >90 known capsular serotypes of S. pneumoni
Externí odkaz:
https://doaj.org/article/6dff269f57c349bba2f847773b586326
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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