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pro vyhledávání: '"S. Papadimitrakopoulou"'
Autor:
J.F. Grippo, Lia Gore, S. G. Eckhardt, S. Mikulski, W. Depinto, Sami Diab, S. Papadimitrakopoulou, Mark DeMario, A. Tan, G. Frenette
Publikováno v:
Journal of Clinical Oncology. 25:3528-3528
3528 Background: R547, a potent inhibitor of CDKs 1, 2, 4, 7, and 9, has shown broad antitumor activity in preclinical models. This phase Ia study assessed safety, pharmacokinetic (PK), and pharmacodynamic (PD) endpoints. Methods: R547 given as a 90