Zobrazeno 1 - 10
of 157
pro vyhledávání: '"S. Pampfer"'
Publikováno v:
Diabetologia. 46:276-283
Previous studies have shown that diabetic placentas are characterized by structural and biochemical anomalies, including defects in the differentiation of trophoblasts. In this study, the Rcho-1 cell line was used to investigate the impact of high gl
Publikováno v:
Diabetologia. 45:571-579
Aims/hypothesis. Signs of apoptosis have been observed in rodent blastocysts exposed to high d-glucose concentrations in vitro. The mechanism underlying the detrimental influence of glucose remains to be identified. It has been postulated that high d
Autor:
S. Pampfer
Publikováno v:
American Journal of Reproductive Immunology. 45:375-381
Insulin-dependent (type I) diabetes is an auto-immune disorder that produces secondary complications in numerous non-immunological systems. Changes in the synthesis and action pattern of several cytokines have been associated with the development of
Autor:
Michel Heusterpreute, S. Pampfer, Isabelle Donnay, Laurence Hinck, Patrick Van Der Smissen, René De Hertogh
Publikováno v:
Biology of Reproduction. 64:555-562
Previous investigations have shown that maternal diabetes impairs rodent embryo development during the earliest phase of gestation. Exposure to high concentrations of glucose before implantation results in a decrease in the number of cells per embryo
Inhibin Subunits mRNA Expression Level in Human Placenta from Normal and Down's Syndrome Pregnancies
Publikováno v:
Placenta. 22:96-102
In order to study the mechanisms leading to increased inhibin A and activin A in maternal serum with advancing gestation and increased inhibin A in Down's syndrome pregnancy, the mRNA expression level of inhibin and activin subunits was quantitativel
Publikováno v:
Molecular Reproduction and Development. 60:38-46
Previous studies have suggested that fibroblast growth factor-4 (FGF-4) may be a paracrine signal used by inner cell mass (ICM) cells to maintain adjacent trophectoderm (TE) cells in an undifferentiated state. In the present work, immunocytochemical
Publikováno v:
Biology of Reproduction. 63:879-886
In order to better understand how tumor necrosis factor (TNF)-alpha may contribute to the local regulation of uterine cell death, cultures of mouse uterine epithelial WEG-1 cells were exposed to TNF-alpha and observed at different time intervals. Ear
Publikováno v:
Molecular Human Reproduction. 6:743-749
Inhibins and activins are dimeric proteins, with each subunit being one of three related protein subunits (alpha, betaA or betaB). The mRNA levels of these subunits were studied quantitatively during in-vitro differentiation of human cytotrophoblast
Autor:
S. Pampfer, José-Enrique O'Connor, Diana Valbuena, R. Herrer, Antonio Pellicer, A. Galán, Cédric Simon, José Remohí
Publikováno v:
Biology of Reproduction. 63:430-439
The implanting blastocyst must appose and adhere to the endometrial epithelium and, subsequently, invade it. Locally regulated uterine epithelial apoptosis induced by the embryo is a crucial step of the epithelial invasion in rodents. To address the
Autor:
S. Pampfer
Publikováno v:
Placenta. 21:S3-S10
Inner cell mass (ICM) and trophectoderm cell lineages diverge early in cleavage in response to a complex combination of cellular and molecular determinative events. The resulting differences in metabolic requirements, cell positioning and micro-envir