Zobrazeno 1 - 10
of 74
pro vyhledávání: '"S. P. Long"'
Autor:
Erin M. Witkop, Kirsten Diggins, Alice Wiedeman, Elisavet Serti, Gerald Nepom, Vivian H. Gersuk, Bryce Fuchs, S. Alice Long, Peter S. Linsley
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Distinct Natural Killer (NK)-like CD57+ and PD-1+ CD8+ exhausted-like T cell populations (Tex) have both been linked to beneficial immunotherapy response in autoimmune type 1 diabetes (T1D) patients. The origins and relationships between the
Externí odkaz:
https://doaj.org/article/8d3fb1a37da44494b3b4cd1c67e7d55e
Autor:
Jamie L. Felton, Maria J. Redondo, Richard A. Oram, Cate Speake, S. Alice Long, Suna Onengut-Gumuscu, Stephen S. Rich, Gabriela S. F. Monaco, Arianna Harris-Kawano, Dianna Perez, Zeb Saeed, Benjamin Hoag, Rashmi Jain, Carmella Evans-Molina, Linda A. DiMeglio, Heba M. Ismail, Dana Dabelea, Randi K. Johnson, Marzhan Urazbayeva, John M. Wentworth, Kurt J. Griffin, Emily K. Sims, On behalf of the ADA/EASD PMDI
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-18 (2024)
Abstract Background Islet autoantibodies form the foundation for type 1 diabetes (T1D) diagnosis and staging, but heterogeneity exists in T1D development and presentation. We hypothesized that autoantibodies can identify heterogeneity before, at, and
Externí odkaz:
https://doaj.org/article/113aed4f5d484c8ca50fd405d635e3a3
Autor:
Paige M. K. Larkin, Elitza S. Theel, Karissa Culbreath, Omai B. Garner, Shannon Vassell, Wes Kim, Rosemary C. She, S. Wesley Long, N. Esther Babady
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/cfbf79dbe9d840adb4915e8f950f99c4
Autor:
Travis J. Kochan, Sophia H. Nozick, Aliki Valdes, Sumitra D. Mitra, Bettina H. Cheung, Marine Lebrun-Corbin, Rachel L. Medernach, Madeleine B. Vessely, Jori O. Mills, Christopher M. R. Axline, Julia A. Nelson, Ethan M. VanGosen, Timothy J. Ward, Egon A. Ozer, David van Duin, Liang Chen, Barry N. Kreiswirth, S. Wesley Long, James M. Musser, Zackery P. Bulman, Richard G. Wunderink, Alan R. Hauser
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Klebsiella pneumoniae has been classified into two types, classical K. pneumoniae (cKP) and hypervirulent K. pneumoniae (hvKP). cKP isolates are highly diverse and important causes of nosocomial infections; they include globally disseminated
Externí odkaz:
https://doaj.org/article/28f7799f087c454c9e785b199d23c81d
Autor:
Jamie L. Felton, Kurt J. Griffin, Richard A. Oram, Cate Speake, S. Alice Long, Suna Onengut-Gumuscu, Stephen S. Rich, Gabriela S. F. Monaco, Carmella Evans-Molina, Linda A. DiMeglio, Heba M. Ismail, Andrea K. Steck, Dana Dabelea, Randi K. Johnson, Marzhan Urazbayeva, Stephen Gitelman, John M. Wentworth, Maria J. Redondo, Emily K. Sims, ADA/EASD PMDI
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-16 (2023)
Abstract Background Type 1 diabetes (T1D) results from immune-mediated destruction of insulin-producing beta cells. Prevention efforts have focused on immune modulation and supporting beta cell health before or around diagnosis; however, heterogeneit
Externí odkaz:
https://doaj.org/article/2767b39b5fa44f12be12f5096aacf63d
Autor:
Jeremy R. B. Newman, S. Alice Long, Cate Speake, Carla J. Greenbaum, Karen Cerosaletti, Stephen S. Rich, Suna Onengut-Gumuscu, Lauren M. McIntyre, Jane H. Buckner, Patrick Concannon
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Genome-wide association studies have identified numerous loci with allelic associations to Type 1 Diabetes (T1D) risk. Most disease-associated variants are enriched in regulatory sequences active in lymphoid cell types, suggesting that lymph
Externí odkaz:
https://doaj.org/article/fc1b48b54b144defac7498b93b2a4cb1
Autor:
Hamid Bolouri, Rhonda E. Ries, Alice E. Wiedeman, Tiffany Hylkema, Sheila Scheiding, Vivian H. Gersuk, Kimberly O’Brien, Quynh-Anh Nguyen, Jenny L. Smith, S. Alice Long, Soheil Meshinchi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
IL6 expression in the bone marrow is associated with reduced survival in paediatric AML. Here, the authors used RNA-seq to identify treatment resistance-associated co-occurring inflammatory signalling in leukemic cells.
Externí odkaz:
https://doaj.org/article/135f6f6b486a456e8346955a1b0198e3
Autor:
Laura M. Jacobsen, Kirsten Diggins, Lori Blanchfield, James McNichols, Daniel J. Perry, Jason Brant, Xiaoru Dong, Rhonda Bacher, Vivian H. Gersuk, Desmond A. Schatz, Mark A. Atkinson, Clayton E. Mathews, Michael J. Haller, S. Alice Long, Peter S. Linsley, Todd M. Brusko
Publikováno v:
JCI Insight, Vol 8, Iss 16 (2023)
BACKGROUND Low-dose anti–thymocyte globulin (ATG) transiently preserves C-peptide and lowers HbA1c in individuals with recent-onset type 1 diabetes (T1D); however, the mechanisms of action and features of the response remain unclear. Here, we chara
Externí odkaz:
https://doaj.org/article/ad46bb6a2d254bafb3f6b3213915a443
Publikováno v:
Tropical Animal Science Journal, Vol 46, Iss 2 (2023)
The study was conducted to determine the relationship between plasma progesterone (P4) concentration on day 6 following artificial insemination (AI) and the pregnancy rate to provide recommendations for measuring P4 concentration before embryo transf
Externí odkaz:
https://doaj.org/article/1785650d491e4f7f966b83bb6e0f6c23
Publikováno v:
Tropical Animal Science Journal, Vol 45, Iss 3 (2022)
The study was carried out to assess factors related to the odds of pregnancy for dairy cattle after treating ovarian disorders in some Northern Vietnamese provinces. A total of 449 ovarian-disordered heifers and cows were given appropriate treatments
Externí odkaz:
https://doaj.org/article/8970f9307270442cabb0794c176e72ec