Zobrazeno 1 - 10
of 68
pro vyhledávání: '"S. P. Bessman"'
Autor:
S P, Bessman, C, Mohan
Publikováno v:
Molecular and cellular biochemistry. 174(1-2)
Our previous studies of insulin action have led us to the finding that insulin acts specifically on the mitochondrial Krebs cycle to stimulate, by 30%, the oxidation of carbons 2 and 3 of pyruvate to CO2. Insulin also stimulates the oxidation of both
Autor:
S G, Golshani-Hebroni, S P, Bessman
Publikováno v:
Journal of bioenergetics and biomembranes. 29(4)
Current thought is that proliferating cells undergo a shift from oxidative to glycolytic metabolism, where the energy requirements of the rapidly dividing cell are provided by ATP from glycolysis. Drawing on the hexokinase-mitochondrial acceptor theo
Publikováno v:
Biochemistry and molecular biology international. 37(6)
Oxidation of [2,3(14)C] and [1,4(14)C] succinate carbons in the mitochondrial Krebs cycle (KC) was used as a probe to investigate the effect of insulin and diabetes on mitochondrial metabolism in isolated rat hepatocytes. The data presented show that
Publikováno v:
Biochemistry and molecular biology international. 37(4)
Diabetes is associated with decreased protein synthesis; however, there have been very few studies on the effects of insulin or diabetes on mitochondrial protein synthesis. We have recently shown that insulin has a direct stimulatory effect on mitoch
Autor:
S P Bessman
Publikováno v:
The American Journal of Clinical Nutrition. 67:357-358
Publikováno v:
Journal of Biological Chemistry. 259:9679-9686
Further studies of mitochondrially bound hexokinase have been carried out in order to elucidate the mechanism first proposed to increase efficiency of oxidative phosphorylation by the acceptor effect (Bessman, S. P. (1954) in Fat Metabolism (Najjar,
Publikováno v:
Journal of Biological Chemistry. 257:14405-14411
In order to define further the nature of the apparent close interaction between mitochondrial creatine phosphokinase and oxidative phosphorylation (Erickson-Viitanen, S., Viitanen, P., Geiger, P. J., Yang, W. C. T., and Bessman, S. P. (1982) J. Biol.
Publikováno v:
Journal of Biological Chemistry. 257:14395-14404
Mitochondrial creatine kinase was first proposed to act as a functional component in respiratory control in 1966 (Bessman, S. P., and Fonyo, A. (1966) Biochem. Biophys. Res. Commun. 22, 597-602). Since that time, evidence has accumulated to support t
Publikováno v:
Diabetes. 25:81-89
A continuous extracorporeal monitoring system for blood glucose employing an electrochemical sensor is described. The sensor, about the size of a nickel, is rapid, is specific for glucose, generates its own power, and consists of two galvanic oxygen
Autor:
S. P. Bessman
Publikováno v:
JAMA: The Journal of the American Medical Association. 197:409-412