Zobrazeno 1 - 10
of 99
pro vyhledávání: '"S. P. Adams"'
Autor:
Christopher JS. Hart, Andrew G. Riches, Snigdha Tiash, Rebecca Abraham, Keely Fayd’Herbe, Ellis Joch, Bilal Zulfiqar, Melissa L. Sykes, Vicky M. Avery, Jan Šlapeta, Sam Abraham, John H. Ryan, Tina S. Skinner-Adams
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 23, Iss , Pp 54-62 (2023)
Giardia duodenalis is the causative agent of the neglected diarrhoeal disease giardiasis. While often self-limiting, giardiasis is ubiquitous and impacts hundreds of millions of people annually. It is also a common gastro-intestinal disease of domest
Externí odkaz:
https://doaj.org/article/3fa7736589924458957c5c2cc3f0b335
Autor:
F. M. Houghton, S. E. Adams, A. S. Ríos, L. Masino, A. G. Purkiss, D. C. Briggs, F. Ledda, N. Q. McDonald
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Glial-cell line derived neurotrophic factor (GDNF) bound to its co-receptor GFRα1 stimulates the RET receptor tyrosine kinase, promoting neuronal survival and neuroprotection. The GDNF-GFRα1 complex also supports synaptic cell adhesion ind
Externí odkaz:
https://doaj.org/article/62b3841fe5224ed7b815d95873e24a85
Publikováno v:
Hydrology and Earth System Sciences, Vol 27, Pp 3021-3039 (2023)
Environmental streamflow management can improve the ecological health of streams by returning modified flows to more natural conditions. The Ecological Limits of Hydrologic Alteration (ELOHA) framework for developing regional environmental flow crite
Externí odkaz:
https://doaj.org/article/86cc0f3e3f6442769028d377335b9f42
Publikováno v:
Frontiers in Conservation Science, Vol 3 (2022)
The global impact of increased human activities has consequences on the conservation of wildlife. Understanding how wildlife adapts to increased human pressures with urban expansion and agricultural areas is fundamental to future conservation plans o
Externí odkaz:
https://doaj.org/article/dc12d5ef256d40f7ae6095fc2fa03ce3
Autor:
Harminder Gill, Heath S. L. Adams, Omar Chehab, Christopher Allen, Jane Hancock, Pablo Lamata, Gianluca Lucchese, Bernard Prendergast, Simon Redwood, Tiffany Patterson, Ronak Rajani
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Transcatheter mitral therapies offer treatment options to selected patients who are unable to undergo open procedures due to prohibitive surgical risk. Data detailing the design and structure of transcatheter mitral services to ensure appropriate pat
Externí odkaz:
https://doaj.org/article/3efc24283c804b9ab1ed3644946c9ad4
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 14, Iss , Pp 249-256 (2020)
The prevention and treatment of malaria requires a multi-pronged approach, including the development of drugs that have novel modes of action. Histone deacetylases (HDACs), enzymes involved in post-translational protein modification, are potential ne
Externí odkaz:
https://doaj.org/article/c65cbe77f8f5495ba8bbb913ad120199
Autor:
Snigdha Tiash, Jake Saunders, Christopher J.S. Hart, John H. Ryan, Andrew G. Riches, Tina S. Skinner-Adams
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 12, Iss , Pp 60-67 (2020)
Giardia duodenalis, the most prevalent human intestinal parasite causes the disease, giardiasis. On an annual basis G. duodenalis infects ~1 billion people, of which ~280 million develop symptomatic disease. Giardiasis can be severe and chronic, caus
Externí odkaz:
https://doaj.org/article/869d3b2bd0794b4aab21dcde3b91fc96
Autor:
Christopher J. S. Hart, Andrew G. Riches, Snigdha Tiash, Erin Clapper, Soumya Ramu, Johannes Zuegg, John H. Ryan, Tina S. Skinner-Adams
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3182 (2022)
On an annual basis the flagellate protozoan, Giardia duodenalis, is responsible for an estimated one billion human infections of which approximately two hundred million cause disease. However, the treatment of Giardia infections is reliant on a small
Externí odkaz:
https://doaj.org/article/4f6dd0a1bdf549999d1439e7cc7483e9
The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides
Autor:
Gillian M. Fisher, Simon A. Cobbold, Andrew Jezewski, Emma F. Carpenter, Megan Arnold, Annie N. Cowell, Erick T. Tjhin, Kevin J. Saliba, Tina S. Skinner-Adams, Marcus C. S. Lee, Audrey Odom John, Elizabeth A. Winzeler, Malcolm J. McConville, Sally-Ann Poulsen, Katherine T. Andrews
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT Plasmodium parasites rely heavily on glycolysis for ATP production and for precursors for essential anabolic pathways, such as the methylerythritol phosphate (MEP) pathway. Here, we show that mutations in the Plasmodium falciparum glycolytic
Externí odkaz:
https://doaj.org/article/610827e8ff5a4ac08e02462e0f5e26af
Publikováno v:
Arid Zone Journal of Engineering, Technology and Environment, Vol 14, Iss 4, Pp 533-539 (2018)
The effect of an inoculant, [triethylamine (TEA)] on the corrosion behavior of multilayered mild steel/Al-Cr plates in guava leaf extract was investigated in 0.5M HCl solution using gravimetric based mass-loss test and potentiodynamic polarization te
Externí odkaz:
https://doaj.org/article/a8817c2613d146d990618149e5931c64