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Autor: Vedran Pavlovic, Edward Gane, Ben Fillippo Krippendorff, Joseph F. Grippo, S Ottosen, Cynthia Wat, Man-Fung Yuen, Henrik Mueller

Publikováno v: Hepatology. 75:1050-1051

Firstly, Dr Vaillant proposes RO7062931 should have exhibited greater HBsAg reductions, given the efficient RO7062931 liver uptake, rapid turnover of HBsAg, and rapid protein reductions observed with GalNAc-ASOs in other therapeutic indications. We f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d96da46efdb22357a58667b750aa1ea6
https://doi.org/10.1002/hep.32113

Miravirsen dosing in chronic hepatitis C patients results in decreased microRNA-122 levels without affecting other microRNAs in plasma

Autor: Harry La Janssen, H. W. Reesink, S. Ottosen, A. J. van der Meer, M.H. van der Ree, A. C. van Nuenen, Neeltje A. Kootstra, J. de Bruijne

Publikováno v: Alimentary Pharmacology & Therapeutics, 43(1), 102-113. Wiley-Blackwell Publishing Ltd
Alimentary pharmacology & therapeutics, 43(1), 102-113. Wiley-Blackwell

Summary Background MicroRNA-122 (miR-122) is an important host factor for hepatitis C virus replication. Administration of miravirsen, an anti-miR-122 oligonucleotide, resulted in a dose dependent and prolonged decrease in HCV RNA levels in chronic h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc68332b681b548c1cce7d7a6ca4043
https://pubmed.ncbi.nlm.nih.gov/26503793

Assessment and significance of diploid-range epithelial populations in DNA aneuploid breast carcinomas using multi-parametric flow cytometry

Autor: D W, Visscher, P, Sochacki, S, Ottosen, S, Wykes, J D, Crissman

Publikováno v: Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology. 8(4)

A 2-color (PI, cytokeratin--FITC) multi-parametric analysis of intact cells was used to reveal diploid-range epithelial populations by flow cytometry in 108 consecutive DNA aneuploid breast carcinomas. Thirty-eight tumors (35%) contained a significan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b0c9b47338f29f3471ecce063febacdd
https://pubmed.ncbi.nlm.nih.gov/7577742

Flow cytometric enumeration and kinetic analysis of inflammatory cell populations in breast carcinomas

Autor: D W, Visscher, G, VanBree, S, Ottosen, S, Wykes, J D, Crissman

Publikováno v: Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology. 5(6)

Inflammatory cell populations were quantitated in 76 consecutive mechanically dissociated clinical breast carcinoma specimens using multiparameter, two-color (PI-cytokeratin/FITC, PI-LCA/FITC) flow cytometric analysis. The percent LCA-positive events

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::21abd923d1c8ecbb62d0ea85da293b70
https://pubmed.ncbi.nlm.nih.gov/8305328

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