Výsledky vyhledávání - "S. Orvokki Mattila"

GPR37 is processed in the N‐terminal ectodomain by ADAM10 and furin

Autor: Xavier Morató, Hanna E. Tuhkanen, S. Orvokki Mattila, Paul Saftig, Anja Konzack, Ulla E. Petäjä-Repo, Josep Argerich, Francisco Ciruela, Jarkko J. Lackman

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona

GPR37 is an orphan G protein-coupled receptor (GPCR) implicated in several neurological diseases and important physiological pathways in the brain. We previously reported that its long N-terminal ectodomain undergoes constitutive metalloprotease-medi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a40c96df6a6b2c9e4428827d871f29
http://hdl.handle.net/2445/178252

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The Parkinson's-disease-associated receptor GPR37 undergoes metalloproteinase-mediated N-terminal cleavage and ectodomain shedding

Autor: Jussi T. Tuusa, S. Orvokki Mattila, Ulla E. Petäjä-Repo

Publikováno v: Journal of cell science. 129(7)

The G-protein-coupled receptor 37 ( GPR37) has been implicated in the juvenile form of Parkinson's disease, in dopamine signalling and in the survival of dopaminergic cells in animal models. The structure and function of the receptor, however, have r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7793b94a76d6f5a3e8aa803b365f74e7
https://pubmed.ncbi.nlm.nih.gov/26869225

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