Výsledky vyhledávání

A Randomized, Phase II Study Evaluating the Efficacy and Safety of Anakinra in the Treatment of Gout Flares

Autor: Robert T. Keenan, S. Ohlman, Kenneth G. Saag, Alexander So, Michael H. Pillinger, Puja P. Khanna, Margareta Wikén, Ann‐Charlotte Åkerblad, Erik Sparve, Lisa Osterling Koskinen, Robert Terkeltaub

Publikováno v: Arthritis & Rheumatology. 73:1533-1542

OBJECTIVE To evaluate the efficacy and safety of anakinra compared to triamcinolone in the treatment of gout flares. METHODS Patients for whom nonsteroidal antiinflammatory drugs and colchicine were not suitable treatments were enrolled in this multi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c475ce999533edff5cb864ef2dd83dc
https://doi.org/10.1002/art.41699

Zobrazit plný text záznamu

Anakinra in children and adults with Still's disease

Autor: Pierre Quartier, Bruno Fautrel, Lisa Osterling Koskinen, Fabrizio De Benedetti, S. Ohlman, Sebastiaan J. Vastert, Karin Franck-Larsson, Torbjörn Kullenberg, Yvan Jamilloux

Publikováno v: Rheumatology
Rheumatology, Oxford University Press (OUP), 2019, 58 (Supplement_6), pp.vi9-vi22. ⟨10.1093/rheumatology/kez350⟩
Rheumatology (United Kingdom), 58(Supplement_6), VI9. Oxford University Press
Rheumatology (Oxford, England)

Systemic juvenile idiopathic arthritis and adult-onset Still’s disease are rare autoinflammatory disorders with common features, supporting the recognition of these being one disease—Still’s disease—with different ages of onset. Anakinra was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1b9e3dde7379c794f4d55b5c698da3
https://hal.sorbonne-universite.fr/hal-02426584/file/kez350.pdf

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

THU0409 A RANDOMIZED, PHASE 2 STUDY EVALUATING THE EFFICACY AND SAFETY OF ANAKINRA IN DIFFICULT-TO-TREAT ACUTE GOUTY ARTHRITIS: THE ANAGO STUDY

Autor: K. Saag, L. Osterling Koskinen, Robert T. Keenan, Torbjörn Kullenberg, Alexander So, Puja P. Khanna, Michael H. Pillinger, S. Ohlman, Robert Terkeltaub

Publikováno v: Annals of the Rheumatic Diseases. 79:442.1-442

Background:In gout, urate crystals deposited in and around joints trigger episodes of acute arthritis, mediated by the proinflammatory cytokine IL-1β. In uncontrolled studies, the IL-1 receptor antagonist anakinra appears effective in reducing pain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d4a537c70d86240b8c5b419920694bb5
https://doi.org/10.1136/annrheumdis-2020-eular.3766

Zobrazit plný text záznamu

AB1059 A RANDOMIZED, PLACEBO-CONTROLLED STUDY OF ANAKINRA IN PATIENTS WITH STILL´S DISEASE

Autor: F De Benedetti, A. Thatayatikom, M. Wikén, H. Andersson, E. Rabinovich, S. Ohlman, Laura E. Schanberg, S. Cederholm, M. Zdravkovic, Peter A. Nigrovic, N. Singh, R. Schneider, A. Taxter, A. Cooper, Jonathan S. Hausmann, S. Akoghlanian, W. Winn Chatham

Publikováno v: Annals of the Rheumatic Diseases. 79:1819.2-1820

Background:Adult-onset Still’s disease (AOSD) and systemic juvenile idiopathic arthritis (SJIA) are rare autoinflammatory disorders associated with an activated IL-1 pathway, characterized by spiking fever, rash, arthritis, lymphadenopathy, hepatos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1aea828ce017442b2c4155bf70f3db4
https://doi.org/10.1136/annrheumdis-2020-eular.2822

Zobrazit plný text záznamu

THU0439 EFFICACY AND SAFETY OF ANAKINRA IN THE TREATMENT OF RECURRENT GOUT FLARES: RESULTS FROM THE EXTENSION PHASE OF THE ANAGO STUDY

Autor: K. Saag, D. Lindqvist, E. Sparve, S. Ohlman, A. C. Åkerblad, Margareta Wikén, Puja P. Khanna, Robert T. Keenan, Robert Terkeltaub, Alexander So, Michael H. Pillinger

Publikováno v: Annals of the Rheumatic Diseases. 79:456.1-457

Background:The anaGO (anakinra ingout) study was a multi-center, randomized, double-blind, double-dummy, phase 2 study investigating the efficacy and safety of anakinra for recurrent gout flares. Results from subsequent flares (extension phase) are p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::501ae3b516e389c321c0718f7b1bac4d
https://doi.org/10.1136/annrheumdis-2020-eular.3813

Zobrazit plný text záznamu

Pharmacokinetics of 15-deoxyspergualin studied in renal transplant patients receiving the drug during graft rejection

Autor: H. Zilg, Anders Lindholm, S. Ohlman, F. Schindel

Publikováno v: Transplant International. 7:5-10

The pharmacokinetics of the novel immunosuppressant 15-deoxyspergualin (DSG) were studied in five renal transplant patients who participated in a dose-finding study for the treatment of renal graft rejection. DSG, in a dose of 4 or 6 mg/kg per day, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b20728c2cd32c9a3bc130b71883ac289
https://doi.org/10.1007/bf00335656

Zobrazit plný text záznamu

Serological responses to human papillomavirus type 16 antigens in women before and after renal transplantation

Autor: Kristina Elfgren, S. Ohlman, Ilona Lewensohn-Fuchs, Daniele Wester, Joakim Dillner, Peter Bistoletti, Tina Dalianis

Publikováno v: Journal of Medical Virology. 40:188-192

Female renal transplant recipients have an increased incidence of human papillomavirus (HPV) associated lesions, such as cervical dysplasia and neoplasia [Schneider et al., 1983]. In this study we tested the serological responses by enzyme-linked imm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26794c717c34069d011a5f44f56a069
https://doi.org/10.1002/jmv.1890400304

Zobrazit plný text záznamu

Rejection associated with early appearance of donor-reactive antibodies after kidney transplantation treated with plasmapheresis and administration of 15-deoxyspergualin

Autor: B. Wikström, L. Weiss, U. Persson, S. Gudmundsson, G. Gannedahl, S. Ohlman, Thomas H. Tötterman, Gunnar Tydén, Erik G. Larsson, Carl-Gustav Groth, Gunnar Tufveson

Publikováno v: Transplant International. 5:189-192

In two kidney transplant patients, one of whom had panel-reactive antibodies (PRA) before transplantation, a pretransplant negative donor-recipient crossmatch became positive within the 1st week after transplantation. Simultaneously, good graft funct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88fd7c4e48ae106663a494d37aaca91
https://doi.org/10.1007/bf00336067

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání