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Akademický článek

Association of TLR4 rs1927911 polymorphism with diabetic retinopathy and diabetic macular edema in type 2 diabetic patients

Autor: S. O. Rykov, Ie. P. Galytska, D. V. Zhmuryk, V. A. Dufynets

Publikováno v: Journal of Ophthalmology, Iss 1, Pp 20-26 (2024)

Background: Genetic susceptibility is a factor in the development of ophthalmic complications in type 2 diabetes mellitus (T2DM). There are differences between polymorphisms of toll-like receptor-4 (TLR4) in terms of their association with microvascu

Externí odkaz: https://doaj.org/article/26ff6955a38b4ec89eebdcefb73e8615

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Akademický článek

Role of polymorphisms of folate-cycle enzymes in diabetic retinopathy progression in patients with type 2 diabetic mellitus

Autor: S. O. Rykov, Iu. V. Prokopenko, L. V. Natrus, Iu. O. Panchenko

Publikováno v: Journal of Ophthalmology, Iss 5, Pp 3-11 (2022)

Background: Hyperhomocysteinemia is important in the development of endothelial dysfunction, a pathogenetic component of diabetic retinopathy (DR) in type 2 diabetes mellitus (DM2). The major cause of homocysteine accumulation is missing or dysfuncti

Externí odkaz: https://doaj.org/article/6a3c21b0e01d49f198e07e4d2be669dd

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Akademický článek

Angiopoietins and prediction of vitreous hemorrhage in type 2 diabetes patients with diabetic retinopathy

Autor: S. O. Rykov, S. Iu. Mogilevskyy, S. S. Lytvynenko, S. V. Ziablitsev

Publikováno v: Journal of Ophthalmology, Iss 1, Pp 3-10 (2022)

Background: Various types of vitreoretinal surgery are used for the treatment of severe diabetic retinopathy (DR), with vitreous hemorrhage being a common postoperative complication. Impaired angiopoietin system function in type 2 diabetes mellitus (

Externí odkaz: https://doaj.org/article/bcd93bcc1862484eb000c526e771dc34

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Akademický článek

A novel concept of differences in pathogenetic mechanism of diabetic retinopathy progression between type 2 diabetes mellitus patients differing in the PPARγ genotype

Autor: L. V. Natrus, S. Yu. Mogilevskyy, T. I. Panova, S. O. Rykov, M. Iu. Bykhovets

Publikováno v: Journal of Ophthalmology, Iss 5, Pp 36-42 (2020)

Background: It is important to study cellular circulation of L-FABP-associated fatty acids (FA) and their oxidation through the classical pathway with activation of the PPARγ gene and under conditions of impaired lipid metabolism. Purpose: To inv

Externí odkaz: https://doaj.org/article/4b6aee05f0634c09b2aba6dbaf119708

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Akademický článek

Pediatric orbital fractures: clinical and CT features and criteria for selecting a treatment option

Autor: A. S. Slobodianiuk, I. V. Chepurnyi, V. P. Efimenko, Iu. V. Shuklina, A. V. Kopchak, O. V. Petrenko, L. M. Iakovenko, S. O. Rykov

Publikováno v: Journal of Ophthalmology, Iss 5, Pp 43-50 (2020)

Background: Pediatric traumatic orbital injuries have a number of clinical and CT features. Purpose: To assess the clinical and CT features of pediatric orbital fractures and the influence of these features on the choice among treatment options, a

Externí odkaz: https://doaj.org/article/8bd158ff27954b40a81f76ae7986b701

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Akademický článek

Blood sICAM-1 levels in type 2 diabetes mellitus patients with various grades of DME

Autor: S.A. Suk, M. L. Kyryliuk, S. O. Rykov

Publikováno v: Journal of Ophthalmology, Iss 5, Pp 18-21 (2019)

Background: Diabetic macular edema (DME) is a major cause of visual impairment in type 2 diabetes mellitus (DM) patients. Non-specific inflammation is an important factor of the underlying processes of DME. Intercellular adhesion molecules (ICAM), pa

Externí odkaz: https://doaj.org/article/f983f7b56f104f0a8feff5fbac52fca2

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