Zobrazeno 1 - 10
of 312
pro vyhledávání: '"S. Nishizaki"'
Autor:
Sierra S. Nishizaki, Alan P. Boyle
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Motivation Aberrant DNA methylation in transcription factor binding sites has been shown to lead to anomalous gene regulation that is strongly associated with human disease. However, the majority of methylation-sensitive positions within tra
Externí odkaz:
https://doaj.org/article/cb121f03249d4f25ad302ccd16382a07
Autor:
Sierra S. Nishizaki, Torrin L. McDonald, Gregory A. Farnum, Monica J. Holmes, Melissa L. Drexel, Jessica A. Switzenberg, Alan P. Boyle
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
BackgroundZebrafish are a foundational model organism for studying the spatio-temporal activity of genes and their regulatory sequences. A variety of approaches are currently available for editing genes and modifying gene expression in zebrafish, inc
Externí odkaz:
https://doaj.org/article/f0362cdfe8ec493ea65ebaf2be9f093f
Autor:
Sierra S. Nishizaki, Natasha Ann F. Mariano, Gabriana N. La, José M. Uribe-Salazar, Gulhan Kaya, Derek Sayre Andrews, Christine Wu Nordahl, David G. Amaral, Megan Y. Dennis
Among autistic individuals, a subphenotype with brain enlargement disproportionate to height (autism with disproportionate megalencephaly, or ASD-DM) seen at three years of age is associated with co-occurring intellectual disability and poorer progno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2af19dc2f6666f6d8bc63f41d3310b65
https://doi.org/10.1101/2022.12.21.22283275
https://doi.org/10.1101/2022.12.21.22283275
Autor:
Alan P. Boyle, Sierra S. Nishizaki
MotivationAberrant DNA methylation in transcription factor binding sites has been shown to lead to anomalous gene regulation that is strongly associated with human disease. However, the majority of methylation-sensitive positions within transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23866f3c15c8a9bfbef825d3fb234c8
Publikováno v:
Journal of Radioanalytical and Nuclear Chemistry. 314:1967-1971
We measured the gamma ray yields of proton and alpha induced reactions on natural calcium in the form of CaO target. The production rates of 43Sc, 44Sc isotopes of medical imaging interest are determined. It is found that alpha production for E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fce90954695869d38e5dff85c6fa0ab3
https://doi.org/10.1007/s10967-017-5515-4
https://doi.org/10.1007/s10967-017-5515-4
Autor:
Alan P. Boyle, Sierra S. Nishizaki
Publikováno v:
Trends in Genetics. 33:34-45
One of the formative goals of genetics research is to understand how genetic variation leads to phenotypic differences and human disease. Genome-wide association studies (GWASs) bring us closer to this goal by linking variation with disease faster th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4580591427debd97d48976a0afb92ca0
https://doi.org/10.1016/j.tig.2016.10.008
https://doi.org/10.1016/j.tig.2016.10.008
Autor:
Natalie Ng, Alan P. Boyle, Shengcheng Dong, Sierra S. Nishizaki, Cody Morterud, Robert S. Porter, Courtney Asman, Jessica A. Switzenberg, Colten Williams
Publikováno v:
Bioinformatics
Motivation Genome-wide association studies have revealed that 88% of disease-associated single-nucleotide polymorphisms (SNPs) reside in noncoding regions. However, noncoding SNPs remain understudied, partly because they are challenging to prioritize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e633a6002d45842672b70b247682715
https://europepmc.org/articles/PMC7999143/
https://europepmc.org/articles/PMC7999143/
Autor:
Alan P. Boyle, Colten Williams, Natalie Ng, Shengcheng Dong, Cody Morterud, Sierra S. Nishizaki
GWAS have revealed that 88% of disease associated SNPs reside in noncoding regions. However, noncoding SNPs remain understudied, partly because they are challenging to prioritize for experimental validation. To address this deficiency, we developed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d339364ab9c4b7b7fc37e614e860a3
Akademický článek
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Autor:
Nadja Makki, Sierra S. Nishizaki, Stephen A. Schlebusch, Zoe Gill, Walter L. Eckalbar, Katherine S. Pollard, Christiane Muswamba-Nday, Ash V Parker, Jeffrey D. Wall, Elizabeth Terhune, Kimberly A. Nevonen, Julia E. VanderMeer, Mandy K. Mason, Nicola Illing, Tara Friedrich, Betty M. Booker, Lucia Carbone, Nadav Ahituv
Publikováno v:
Nature genetics
Bats are the only mammals capable of powered flight, but little is known about the genetic determinants that shape their wings. Here we generated a genome for Miniopterus natalensis and performed RNA-seq and ChIP-seq (H3K27ac and H3K27me3) analyses o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::954f7da8af8e1ded426da46769ba664a
https://doi.org/10.1038/ng.3537
https://doi.org/10.1038/ng.3537