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of 3
pro vyhledávání: '"S. Nilgün Çömezoglu"'
Autor:
Sridhar Mani, Susan B. Horwitz, Gary Goldberg, Hayley McDaid, W. Griffith Humphreys, Carrie Xu, Donglu Zhang, Van T. Ly, Adriana Comprelli, Lisa Iacono, David Jayabalan, François André, Lionel Perrin, S. Nilgün Çömezoglu, Marvin Cohen, Sanjay Goel
Supplementary Data from The Effect of Ketoconazole on the Pharmacokinetics and Pharmacodynamics of Ixabepilone: A First in Class Epothilone B Analogue in Late-Phase Clinical Development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699687c0c30295f2d1de845abad7ce93
https://doi.org/10.1158/1078-0432.22439589
https://doi.org/10.1158/1078-0432.22439589
Autor:
Sridhar Mani, Susan B. Horwitz, Gary Goldberg, Hayley McDaid, W. Griffith Humphreys, Carrie Xu, Donglu Zhang, Van T. Ly, Adriana Comprelli, Lisa Iacono, David Jayabalan, François André, Lionel Perrin, S. Nilgün Çömezoglu, Marvin Cohen, Sanjay Goel
Purpose: To determine if ixabepilone is a substrate for cytochrome P450 3A4 (CYP3A4) and if its metabolism by this cytochrome is clinically important, we did a clinical drug interaction study in humans using ketoconazole as an inhibitor of CYP3A4.Exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::859f1d308bd5da29c4621d29624d656f
https://doi.org/10.1158/1078-0432.c.6517026
https://doi.org/10.1158/1078-0432.c.6517026
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