Zobrazeno 1 - 10
of 308
pro vyhledávání: '"S. Nadler"'
Autor:
Monica J. S. Nadler, Weipang Chang, Ekim Ozkaynak, Yuda Huo, Yi Nong, Morgane Boillot, Mark Johnson, Antonio Moreno, Matthew P. Anderson
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Human-specific SINE-VNTR-Alu (SVA) retrotransposons in neurodevelopmental genes CDK5RAP2 and SCN8A repress their expression to delay neuronal maturation. SVA-lncRNA AK057321 binds these SVAs to release gene repression and drive neuronal maturation.
Externí odkaz:
https://doaj.org/article/aca25956f52c469ba5776582c1a9a221
Akademický článek
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Publikováno v:
Ann Neurol
Objective Autism spectrum disorder (ASD) affects 1 in 59 children, yet except for rare genetic causes, the etiology in most ASD remains unknown. In the ASD brain, inflammatory cytokine and transcript profiling shows increased expression of genes enco
Publikováno v:
Diabetes & Metabolism. 47:101165
Autor:
Bodvael Pennarun, Anja Schempf, Bo Yang, Parisa Mousavi Shafaei, Da Yang, Dipak Datta, Barbara L. Hopkins, Steffi Oesterreich, Octavian Bucur, Thierry Bertomeu, John J. Skoko, Andrea Pelosi, Kenneth Ndebele, Carola A. Neumann, Kevin M. Levine, Monica J. S. Nadler, Maria Giulia Rizzo, Roya Khosravi-Far
Publikováno v:
Antioxidants & Redox Signaling
Precision in redox signaling is attained through posttranslational protein modifications such as oxidation of protein thiols. The peroxidase peroxiredoxin 1 (PRDX1) regulates signal transduction through changes in thiol oxidation of its cysteines. We
Autor:
Mark Duquette, Jack Lawler, Monica J. S. Nadler, Trevor J. Shuttleworth, Dayne Okuhara, Jill L. Thompson
Publikováno v:
Matrix biology : journal of the International Society for Matrix Biology
The thrombospondins (TSPs) are a family of matricellular proteins that regulate cellular phenotype through interactions with a myriad of other proteins and proteoglycans. We have identified a novel interaction of the members of the TSP gene family wi
Poor antibody validation is a challenge in biomedical research: a case study for detection of c-FLIP
Autor:
Maria Sinziana Muraru, Thierry Bertomeu, Octavian Bucur, Andreea Lucia Stancu, Monica J. S. Nadler, Bodvael Pennarun, Roya Khosravi-Far
Publikováno v:
Apoptosis. 18:1154-1162
Successful translation of findings derived from preclinical studies into effective therapies is critical in biomedical research. Lack of robustness and reproducibility of the preclinical data, due to insufficient number of repeats, inadequate cell-ba
Autor:
Kathryn G. Klemic, Abdallah Badou, Usha Govindarajulu, Judith Stein, Jean-Pierre Kinet, Didi Matza, Oz M. Shapira, Leonard K. Kaczmarek, Richard A. Flavell, Amnon Peled, Monica J. S. Nadler
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147379 (2016)
PLoS ONE
PLoS ONE
The process of calcium entry in T cells is a multichannel and multi-step process. We have studied the requirement for L-type calcium channels (Cav1.1) α1S subunits during calcium entry after TCR stimulation. High expression levels of Cav1.1 channels
Kniha
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Autor:
Marie Laloi-Michelin, J. Cahen-Varsaux, J.-F. Blickle, B Delemer, J. Mausset, A. Sola-Gazagnes, Eric Bertin, S. Schneebeli, Sandrine Beaufils, D. Paris-Bockel, T. Crea, Lise Bernard, Bernard Vialettes, T. Gabreau, A. Cailleba, J. L. Thomas, F. Olivier, Jean-Pierre Riveline, Jacques Louis, Danièle Dubois-Laforgue, Pierre-Henri Ducluzeau, C. Ambonville, P. Cathebras, S. Casanova, Béatrice Bouhanick, F. Lorenzini, Pascale Massin, S. Nadler-Fluteau, José Timsit, Guillaume Charpentier, P. Chedin, H. Gin, A. Murat, Yves Reznik, E. Larger, A. Grimaldi, T. Meas, Pierre-Jean Guillausseau, Bernard Bauduceau, Bruno Guerci, L. Dusselier, B. Trabulsi, E. Sonnet, I. Raynaud, F. Duchemin, V. Jacquin, C. Bellanné-Chantelot, A. Lecleire-Collet, E. Kaloustian, Véronique Paquis-Flucklinger, Marie Virally
Publikováno v:
The Journal of clinical endocrinology & metabolism
The Journal of clinical endocrinology & metabolism, 2009, 94 (8), pp.3025-3030. ⟨10.1210/jc.2008-2680⟩
The Journal of clinical endocrinology & metabolism, 2009, 94 (8), pp.3025-3030. ⟨10.1210/jc.2008-2680⟩
International audience; Context: Maternally inherited diabetes and deafness (MIDD) is a rare form of diabetes with a matrilineal transmission, sensorineural hearing loss, and macular pattern dystrophy due to an A to G transition at position 3243 of m