Genetics of susceptibility to tuberculosis in humans

Autor: M.J. Newport, S. Nejentsev

Publikováno v: Monaldi Archives for Chest Disease, Vol 61, Iss 2 (2004)

There is substantial epidemiological evidence that host genetic factors in part determine susceptibility to mycobacteria, and many approaches have been applied to identify the specific genes involved. These include the study of single genes in ‘kno

Externí odkaz: https://doaj.org/article/11a454bb8879462086c1eec456d5cd51

Humoral responses after second and third SARS-CoV-2 vaccination in patients with immune-mediated inflammatory disorders on immunosuppressants: a cohort study

Autor: Luuk Wieske, Koos P J van Dam, Maurice Steenhuis, Eileen W Stalman, Laura Y L Kummer, Zoé L E van Kempen, Joep Killestein, Adriaan G Volkers, Sander W Tas, Laura Boekel, Gerrit J Wolbink, Anneke J van der Kooi, Joost Raaphorst, Mark Löwenberg, R Bart Takkenberg, Geert R A M D'Haens, Phyllis I Spuls, Marcel W Bekkenk, Annelie H Musters, Nicoline F Post, Angela L Bosma, Marc L Hilhorst, Yosta Vegting, Frederike J Bemelman, Alexandre E Voskuyl, Bo Broens, Agner Parra Sanchez, Cécile A C M van Els, Jelle de Wit, Abraham Rutgers, Karina de Leeuw, Barbara Horváth, Jan J G M Verschuuren, Annabel M Ruiter, Lotte van Ouwerkerk, Diane van der Woude, Renée C F Allaart, Y K Onno Teng, Pieter van Paassen, Matthias H Busch, Papay B P Jallah, Esther Brusse, Pieter A van Doorn, Adája E Baars, Dirk Jan Hijnen, Corine R G Schreurs, W Ludo van der Pol, H Stephan Goedee, Sofie Keijzer, Jim B D Keijser, Arend Boogaard, Olvi Cristianawati, Anja ten Brinke, Niels J M Verstegen, Koos A H Zwinderman, S Marieke van Ham, Taco W Kuijpers, Theo Rispens, Filip Eftimov, R. de Jongh, C.E. van de Sandt, L. Kuijper, M. Duurland, R.R. Hagen, J. van den Dijssel, C. Kreher, A. Bos, V. Palomares Cabeza, V.A.L. Konijn, G. Elias, J.G. Vallejo, M.J. van Gils, T.M. Ashhurst, S. Nejentsev, E.S. Mirfazeli

Publikováno v: The Lancet Rheumatology, 4(5), e338-e350. Elsevier
The Lancet. Rheumatology, 4(5), e338-e350. Elsevier Ltd
The Lancet Rheumatology, 4(5), E338-E350. ELSEVIER
T2B! immunity against SARS-CoV-2 study group 2022, ' Humoral responses after second and third SARS-CoV-2 vaccination in patients with immune-mediated inflammatory disorders on immunosuppressants : a cohort study ', The Lancet Rheumatology, vol. 4, no. 5, pp. e338-e350 . https://doi.org/10.1016/S2665-9913(22)00034-0
The Lancet Rheumatology, 4(5), e338-e350. Lancet Publishing Group
The Lancet Rheumatology, 4(5), E338-E350. Lancet Publishing Group

Background: Disease-specific studies have reported impaired humoral responses after SARS-CoV-2 vaccination in patients with immune-mediated inflammatory disorders treated with specific immunosuppressants. Disease-overarching studies, and data on reca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32cd7639bd3c42720d60a555471f4e04
https://pubmed.ncbi.nlm.nih.gov/35317410

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Analysis of extended human leukocyte antigen haplotype association with Addison's disease in three populations

Autor: Koit Reimand, Zsofia Gombos, S Nejentsev, V Fadeyev, Robert Hermann, Pärt Peterson, Jorma Ilonen, Raivo Uibo, Minna Kiviniemi

Publikováno v: European Journal of Endocrinology. 157:757-761

ObjectiveAddison's disease is an organ-specific autoimmune disorder with a polygenic background. The aim of the study was to identify non-class II human leukocyte antigen (HLA) susceptibility genes for Addison's disease.Design and methodsAddison's di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626d93744c2d398831003a66fc40c086
https://doi.org/10.1530/eje-07-0290

Population-based genetic screening for the estimation of Type 1 diabetes mellitus risk in Finland: selective genotyping of markers in the HLA-DQB1, HLA-DQA1 and HLA-DRB1 loci

Autor: Olli Simell, Minna Sjöroos, Mikael Knip, T Soukka, Jorma Ilonen, S Nejentsev, Timo Lövgren

Publikováno v: Diabetic Medicine. 16:985-992

Summary Aims To improve sensitivity and specificity of the diabetes risk assessment of the population-based genetic screening used in the Finnish Diabetes Prediction and Prevention (DIPP) trial. Methods One thousand consecutive newborns enrolled in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf813923c30df5e1e538e53f5141479
https://doi.org/10.1046/j.1464-5491.1999.00186.x