Zobrazeno 1 - 9
of 9
pro vyhledávání: '"S. N. Ptitsina"'
Publikováno v:
Pharmaceutical Chemistry Journal. 48:292-297
A validated assay for quantitation of letrozole (selective non-steroidal aromatase inhibitor) in human blood plasma using tandem LC-MS/MS was proposed. Biological samples were processed beforehand by solid-phase extraction over SOLA cartridges. The c
Autor:
V. I. Bobrov, L. N. Sernov, I. Kh. Ivanova, S. N. Ptitsina, M. M. Borisov, I. I. Miroshnichenko
Publikováno v:
Pharmaceutical Chemistry Journal. 41:625-628
A new high-performance liquid chromatographic method with ultraviolet detection has been used to determine the levels of the new cardiotropic drug protecor in the blood of animals (chincilla rabbits, 2.2 ± 0.2 kg; and beagle dogs, 10 ± 0.5 kg). The
Publikováno v:
Pharmaceutical Chemistry Journal. 41:294-296
The pharmacokinetics of various therapeutic forms of azithromycin of Russian origin (suspension, tablets, capsules) after oral administration to rabbits were studied using a microbiological agar diffusion method with the test microbe Micrococcus lute
Autor:
S. N. Ptitsina, V. I. Bobrov, M. M. Borisov, I. Kh. Ivanova, L. N. Serov, I. I. Miroshnichenko
Publikováno v:
Pharmaceutical Chemistry Journal. 40:683-685
An HPLC-based method with ultraviolet detection has been developed for determining the new cardiotropic drug protecor in the blood and applied to monitoring of the drug pharmacokinetics after intravenous administration in experimental animals (rabbit
Autor:
A. D. Mehandjiev, S. A. Sergeeva, E. D. Blagoeva, S. N. Ptitsina, Stephka Chankova, V. A. Shevchenko
Publikováno v:
Biologia plantarum. 36:583-589
This paper compares the repair of DNA single strand breaks (ssb) induced by γ-radiation in two strains ofChlamydomonas reinhardtii (137C/+/ and UVS-I) and three lines ofPisum sativum (NN 131, 198, 140) differing in the degree of radioresistance. DNA
Publikováno v:
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 52(6)
Therapeutic activity, pharmacokinetic and bioavailability on animals (inbred white mouse, rabbits) were evaluated for Ofloxacin-PhPO and Pefloxacin-genova in comparison with innovator products--Tarivid and Abaktal. The results of the experiments demo
Publikováno v:
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 51(11-12)
Pharmacokinetics and bioavailability of the antimycotics ketoconazole FPO and fluconazole (Russia) and the analogous drugs nizoral (Belgium) and diflucan (France) were comparatively studied on animals and in clinical trials. The pharmacokinetic param
Publikováno v:
Radiatsionnaia biologiia, radioecologiia. 37(4)
Long-time in vivo influence of chemical mutagens in low doses can decrease the level of unscheduled DNA synthesis (UDS) induced in human as well as in laboratory mammals. The phenomenon under investigation is not specific neither for chronically acti
Autor:
S G, Chankova, A D, Mehandjiev, E D, Blagoeva, D A, Angelov, E, Keskinova, S A, Sergeeva, V A, Shevchenko, S N, Ptitsina, A B, Syemov
Publikováno v:
Acta biologica Hungarica. 41(1-3)
Two cell repair systems--photoreactivation and repair of single-strand DNA breaks have been studied using unicellular green algae as a test-system. Effects of the genotype and the intensity of pico/second UV-laser irradiation on the degree of the pho