Differential expression of genes encoding CD30L and P-selectin in cattle with Johne's disease: Progress toward a diagnostic gene expression signature

Autor: Chas B. Pudrith, Kerstin Skovgaard, Gregers Jungersen, S. N. Grell, Paul M. Coussens, Peter M. H. Heegaard

Publikováno v: Veterinary Immunology and Immunopathology. 112:210-224

Mycobacterium avium subspecies paratuberculosis (Mycobacterium paratuberculosis), the causative agent of paratuberculosis (paraTB) or Johne's disease in ruminants, is a health problem for the global cattle industry with significant economic losses re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e82b8c6cf004dadf57cdfbd41ba56a78
https://doi.org/10.1016/j.vetimm.2006.02.006

Aerosol challenge of calves with Haemophilus somnus and Mycoplasma dispar

Autor: S. N. Grell, Ulla Riber, Øystein Angen, Conny Tegtmeier, N.F. Friis

Publikováno v: Veterinary Microbiology

The aim of the study was to examine the ability of Haemophilus somnus and Mycoplasma dispar to induce pneumonia in healthy calves under conditions closely resembling the supposed natural way of infection, viz. by inhalation of aerosol droplets contai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e353ede13a95d30efd302a8ab07b360
https://doi.org/10.1016/s0378-1135(99)00181-9

Marked induction of IL-6, haptoglobin and IFNgamma following experimental BRSV infection in young calves

Autor: Kirsten Tjørnehøj, Lars Erik Larsen, Peter M. H. Heegaard, S. N. Grell

Publikováno v: Veterinary immunology and immunopathology. 103(3-4)

Bovine respiratory syncytial virus (BRSV) has been identified worldwide as an important pathogen associated with acute respiratory disease in calves. An infection model has been developed reflecting accurately the clinical course and the development

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1145280e2f085c6116142c697606a6
https://pubmed.ncbi.nlm.nih.gov/15690587

Development and Validation of a Novel ELISA for the Specific Detection of Antibodies against Mycobacterium avium Subspecies paratuberculosis Based on a Chimeric Polyprotein.

Autor: Moyano, Roberto Damián¹ (AUTHOR), Romero, Magali Andrea² (AUTHOR), Colombatti Olivieri, María Alejandra¹ (AUTHOR), Alvarado Pinedo, María Fiorella³ (AUTHOR), Traveria, Gabriel Eduardo³ (AUTHOR), Romano, María Isabel¹ (AUTHOR), Alonso, María Natalia¹ (AUTHOR)

Publikováno v: Veterinary Medicine International. 12/29/2021, p1-10. 10p.

NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia

Autor: Erik Hulegårdh, Bendik Lund, Marie Grosjean, Ramneek Gupta, Morten Tulstrup, William L. Carroll, Kaie Pruunsild, Jacob Nersting, Zeyu Zhang, Marlene Danner Dalgaard, Nina Toft, Peder Skov Wegener, Mari Punab, Goda Vaitkeviciene, Jinhua Wang, Kathrine Grell, Stine Nygaard Nielsen, Sigurd Liestol, Olafur G. Jonsson, Benjamin Ole Wolthers, Laimonas Griskevicius, Arja Harila-Saari, Jonas Abrahamsson, Mette Holm, Kjeld Schmiegelow

Publikováno v: Tulstrup, M, Grosjean, M, Nielsen, S N, Grell, K, Wolthers, B O, Wegener, P S, Jonsson, O G, Lund, B, Harila-Saari, A, Abrahamsson, J, Vaitkeviciene, G, Pruunsild, K, Toft, N, Holm, M, Hulegårdh, E, Liestøl, S, Griskevicius, L, Punab, M, Wang, J, Carroll, W L, Zhang, Z, Dalgaard, M D, Gupta, R, Nersting, J & Schmiegelow, K 2018, ' NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia ', Leukemia, vol. 32, no. 12, pp. 2527–2535 . https://doi.org/10.1038/s41375-018-0245-3
Tulstrup, M, Grosjean, M, Nielsen, S N, Grell, K, Wolthers, B O, Wegener, P S, Jonsson, O G, Lund, B, Harila-Saari, A, Abrahamsson, J, Vaitkeviciene, G, Pruunsild, K, Toft, N, Holm, M, Hulegårdh, E, Liestøl, S, Griskevicius, L, Punab, M, Wang, J, Carroll, W L, Zhang, Z, Dalgaard, M D, Gupta, R, Nersting, J & Schmiegelow, K 2018, ' NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia ', Leukemia, vol. 32, no. 12, pp. 2527-2535 . https://doi.org/10.1038/s41375-018-0245-3

The antileukaemic drug 6-mercaptopurine is converted into thioguanine nucleotides (TGN) and incorporated into DNA (DNA-TG), the active end metabolite. In a series of genome-wide association studies, we analysed time-weighted means (wm) of erythrocyte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf51d044bbd21434cfe199ab46207ed
https://pubmed.ncbi.nlm.nih.gov/30201983