Zobrazeno 1 - 10
of 14
pro vyhledávání: '"S. N. Belzhelarskaia"'
Autor:
Sattov F, S. N. Belzhelarskaia
Publikováno v:
Molecular Biology. 38:400-404
Baculovirus-mediated cloning and expression of the mouse serotonin receptor (5HT1c) cDNA in insect cells was proposed to create an alternative to the oocyte-based system commonly employed in electrophysiological studies of ionic channels. A recombina
Autor:
O V, Orlova, V L, Drutsa, P V, Spirin, V I, Popenko, V S, Prasolov, P M, Rubtsov, S N, Kochetkov, S N, Belzhelarskaia
Publikováno v:
Molekuliarnaia biologiia. 47(1)
Envelope proteins of HCV play a major role in virus lifecycle. These proteins are main components of the virion. They are involved in virus assembly. Envelope proteins are modified by N-linked glycosylation which is supposed to play a role in their s
Autor:
A V, Timokhova, L V, Bakinovskiĭ, A I, Zinin, V I, Popenko, A V, Ivanov, P M, Rubtsov, S N, Kochetkov, S N, Belzhelarskaia
Publikováno v:
Molekuliarnaia biologiia. 46(4)
Viral hepatitis C is one of the wide-spread and dangerous human diseases. The choice of drugs for treatment of chronic hepatitis C virus (HCV) infection is limited and prophylactic vaccines do not exist. Thus, the development of new antiviral strateg
Autor:
S N, Belzhelarskaia
Publikováno v:
Molekuliarnaia biologiia. 45(1)
The baculovirus vector systems has been extensively used for the expression of foreign gene products in insect and mammalian cells. New advances increase the possibilities and applications of the baculovirus expression system, which has the capabilit
Autor:
N N, Koroleva, P V, Spirin, A V, Timokhova, P M, Rubtsov, S N, Kochetkov, V S, Prasolov, S N, Belzhelarskaia
Publikováno v:
Molekuliarnaia biologiia. 44(3)
Baculovirus expression vectors are extensively used for the delivering foreign genes and expression of recombinant proteins in insect and mammalian cells. Modified baculoviruses containing mammalian promoter elements (BacMam viruses) for an efficient
Publikováno v:
Molekuliarnaia biologiia. 41(1)
Steroid 21-hydroxylase is a key enzyme of glucocorticoid and mineralocorticoid biosynthesis in the adrenal gland that belongs to the family of microsomal cytochrome P450. The steroid 21-hydroxylase deficiency is the most frequent cause of the congeni
Autor:
N N, Koroleva, Iu V, Grishchuk, S V, Kochetkova, V S, Prasolov, P M, Rubtsov, S N, Belzhelarskaia
Publikováno v:
Molekuliarnaia biologiia. 40(6)
The fragments of genomics DNA of the nuclear polyhedrosis virus (NPV) containing genes of late viral proteins p10, p35, p39, were cloned, the promoter regions of this genes were used to design baculovirus transfer vectors. A double-promoter and tripl
Autor:
S N, Belzhelarskaia, F, Sattov
Publikováno v:
Molekuliarnaia biologiia. 38(3)
Baculovirus-mediated cloning and expression of the mouse serotonin receptor (5HT1c) cDNA in insect cells was proposed to obtain an alternative to an oocyte-based system, which is commonly employed in electrophysiological studies of ionic channels. A
Autor:
S N, Belzhelarskaia, F, Sutton
Publikováno v:
Molekuliarnaia biologiia. 37(3)
The recombinant mouse brain serotonin receptor (5HT1c) was used to study the response of plant cells and oocytes to a stress signal activated by the serotonin-serotonin receptor interaction and associated Ca2+ flow. Based on plant expression vectors,
Autor:
S N, Belzhelarskaia
Publikováno v:
Molekuliarnaia biologiia. 36(3)
The review considers the biology of baculoviruses, construction of transfer vectors for the baculovirus expression system, selection of recombinant baculoviruses, approaches to expression of multimeric proteins, and the potentialities and prospects o