Zobrazeno 1 - 10
of 161
pro vyhledávání: '"S. Mutafov"'
Publikováno v:
Eng Life Sci
The achievement of an effective process of 9α‐hydroxylation of 4‐androstene‐3,17‐dione is of significant importance as it leads to the formation of the key intermediate 9α‐hydroxy‐4‐androstene‐3,17‐dione which is not possible by c
Publikováno v:
Journal of Drug Metabolism & Toxicology. 7
The aim of the paper is to present microbial transformation reactions as a step in the preparation of drugs or their key intermediates from plant derived compounds. Described are some successful applications of microbial transformation processes for
Autor:
Tatyana Avramova, Svetlana Momchilova, B. Angelova, Lilyana Boyadjieva, Boryana Damyanova, S. Mutafov, Dimitrina Spassova
Publikováno v:
World Journal of Microbiology and Biotechnology. 26:1009-1014
Studied is the effect of the non-ionic surfactant Tween 80 on the microbial transformation of 4-androstene-3,17-dione into its 9α-hydroxy-derivative by resting Rhodococcus sp. cells. The surfactant was applied in the cultivation medium as an additio
Publikováno v:
Biodegradation. 19:387-393
Studied was the effect of temperature in the range 12–46 °C on the rate of bacterial decolorization of the mono-azo dye Acid Orange 7 by Alcaligenes faecalis 6132 and Rhodococcus erythropolis 24. With both strains the raise of temperature led to a
Publikováno v:
World Journal of Microbiology and Biotechnology. 23:417-422
The abilities of two bacterial strains of opposite tinctorial type, the Gram-negative Alcaligenes faecalis and the Gram-positive Rhodococcus erythropolis, to decolorize reaction medium containing initially 10, 50, 100, 200 and 500 mg l−1 of the mon
Publikováno v:
Enzyme and Microbial Technology. 37:718-722
The use of organic solvent-based media for microbial 9α-hydroxylation of androstenedione (AD) by resting Rhodococcus sp. cells was evaluated. Product yields higher than 90% were observed in a two-phase phthalate-buffer transformation medium (3:1, v/
Publikováno v:
Biotechnology & Biotechnological Equipment. 19:113-116
The influence of the source of nitrogen in the cultivation media on 9α-hydroxylating activity of resting Rhodococcus sp. cells was investigated. Two pregnane steroids 3β-hydroxy-16α,17α-epoxy-5α-pregnane-20-one (5α-H) and 3β-hydroxy-16α,17α-
Publikováno v:
Process Biochemistry. 32:585-589
The inducibility of the key enzyme systems controlling the microbial 9α-hydroxylation of 4-androstene-3,17-dione (AD) by resting Rhodococcus sp. IOC-77 cells was investigated. Consecutive induction of the 9α-steroid hydroxylating activity and the a
Autor:
M. E. Michailov, K. Y. Stavrev, Milcho Tsvetkov, Evgeni Semkov, Katya Tsvetkova, A. S. Mutafov
Publikováno v:
Open Astronomy, Vol 6, Iss 2, Pp 271-274 (1997)
Publikováno v:
Process Biochemistry. 31:179-184
The effect of nitrogen and carbon nutrition, growth and biomass storage on the effectiveness of microbial 9α-hydroxylation of 4-androstene-3,17-dione was studied. The transformation was carried out by resting Rhodococcus sp. cells in nutrient defici