Zobrazeno 1 - 10
of 538
pro vyhledávání: '"S. Muranishi"'
Publikováno v:
Pharmaceutical research. 3(2)
We attempted to enhance the rectal absorption of human fibroblast interferon (HuIFN-β) in rats by the administration of suppositories containing fusogenic lipid and a nontoxic surfactant. Suppositories containing either the lipid (linoleic acid) or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::57cdd744f3c1a4ef59999de5bf1c12d4
https://pubmed.ncbi.nlm.nih.gov/24271471
https://pubmed.ncbi.nlm.nih.gov/24271471
Publikováno v:
Pharmaceutical research. 2(5)
Cefmetazole distribution into mice cerebral cortex was minimal when the drug was administered alone. However, the co-administration of salicylate or diethyl maleate enhanced cefmetazole uptake into the cerebral cortex, while it decreased the level of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::adfb81742e0e426866963f3bd65fe6a1
https://pubmed.ncbi.nlm.nih.gov/24272845
https://pubmed.ncbi.nlm.nih.gov/24272845
Publikováno v:
Pharmaceutical research. 3(1)
The absorption and lymphatic delivery of a new immunosuppressive drug, cyclosporin A (CsA), were studied in rats by administering CsA orally after solubilization with HCO-60 (polyoxyethylated hydrogenated castor oil), sugar ester, and oils. After the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b2e97147bb581c62d707d90727095d9
https://pubmed.ncbi.nlm.nih.gov/24271357
https://pubmed.ncbi.nlm.nih.gov/24271357
Publikováno v:
Pharmaceutical research. 3(1)
The effect of oleic acid vesicles (ufasomes) on the intestinal absorption of entrapped carboxyfluo-rescein (CF) was investigated by an in situ closed-loop method in rats. Entrapment of CF in ufasomes enhanced the absorption of CF at the earlier stage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9d4ff2b24e325999c368f0115fb925da
https://pubmed.ncbi.nlm.nih.gov/24271354
https://pubmed.ncbi.nlm.nih.gov/24271354
Autor:
S, Muranishi
Publikováno v:
Pharmaceutical research. 2(3)
The use of various lipids for the modification of intestinal absorption of lipophilic, hydrophilic, or macromolecular drugs is reviewed. The influence of lipids on drug absorption varies with the structure and physical state of incorporated lipids. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5ec81fcb2d4a1ee388fd5f216069814
https://pubmed.ncbi.nlm.nih.gov/24272687
https://pubmed.ncbi.nlm.nih.gov/24272687
Publikováno v:
Pharmaceutical research. 2(5)
Enhancement of human leucocyte interferon (HuIFN-α) absorption from rat large intestine was studied with the aid of lipid, surfactant and lipid-surfactant mixed micelles. Neither the emulsified lipid (linoleic acid) nor the surfactant (HCO60, polyox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d6e36cd45c61ba5b991fb0f48ed3ef53
https://pubmed.ncbi.nlm.nih.gov/24272847
https://pubmed.ncbi.nlm.nih.gov/24272847
Akademický článek
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Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 76(3)
The absorption of water soluble compounds with different molecular weights, such as phenol red (MW 354), trypan blue (MW 960), fluorescein isothiocyanate dextrans, (MW 4400 and 9100) was studied in the lung, nasal cavity, buccal cavity, small and lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2fcc4d811d4fe500fe350b55ec872cd
https://pubmed.ncbi.nlm.nih.gov/11578749
https://pubmed.ncbi.nlm.nih.gov/11578749
Autor:
T, Uchiyama, A, Kotani, H, Tatsumi, T, Kishida, A, Okamoto, N, Okada, M, Murakami, T, Fujita, Y, Fujiwara, Y, Kiso, S, Muranishi, A, Yamamoto
Publikováno v:
Pharmaceutical research. 17(12)
The objective of this study is to examine the intestinal permeability of novel lipophilic derivatives of DADLE (Tyr-D-Ala-Gly-Phe-D-Leu), an enkephalin analogue, using isolated rat intestinal membranes.The novel lipophilic derivatives of DADLE were s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05d2f093d106810ee6390766c9a0c4c2
https://pubmed.ncbi.nlm.nih.gov/11303954
https://pubmed.ncbi.nlm.nih.gov/11303954
Autor:
H, Tozaki, J, Nishioka, J, Komoike, N, Okada, T, Fujita, S, Muranishi, S I, Kim, H, Terashima, A, Yamamoto
Publikováno v:
Journal of pharmaceutical sciences. 90(1)
The objective of this study was to estimate colon-specific delivery of insulin and (Asu(1,7))eel-calcitonin using novel azopolymer-coated pellets. In vitro drug-release experiments from the azopolymer-coated pellets containing fluorescein isothiocyan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ff1e74884e020839b6071c19c9a2349
https://pubmed.ncbi.nlm.nih.gov/11064382
https://pubmed.ncbi.nlm.nih.gov/11064382