Zobrazeno 1 - 10
of 186
pro vyhledávání: '"S. Muntean"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Autosomal dominant polycystic kidney disease (PKD) is a hereditary disorder affecting multiple organs, including the heart. PKD has been associated with many cardiac abnormalities including the arrhythmogenic remodeling in clinical evaluations. In ou
Externí odkaz:
https://doaj.org/article/f289db4cd2e44f1ab3d297ac61ed365e
Autor:
Brian S. Muntean, Stefano Zucca, Courtney M. MacMullen, Maria T. Dao, Caitlin Johnston, Hideki Iwamoto, Randy D. Blakely, Ronald L. Davis, Kirill A. Martemyanov
Publikováno v:
Cell Reports, Vol 22, Iss 1, Pp 255-268 (2018)
Summary: Modulation of neuronal circuits is key to information processing in the brain. The majority of neuromodulators exert their effects by activating G-protein-coupled receptors (GPCRs) that control the production of second messengers directly im
Externí odkaz:
https://doaj.org/article/207ebaaf212843c9b8f60c16dd36bffd
Publikováno v:
The Scientific Bulletin of Electrical Engineering Faculty. 22:60-64
The goal of this paper is to present the benefits of digitalization and Internet of Things applied in various fields of industry, including in cereal reception bases. Using Waterfall Methodology, this article widely describes the project plan of a we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffa08259be2ec430ce363db038b0cff9
https://doi.org/10.2478/sbeef-2022-0022
https://doi.org/10.2478/sbeef-2022-0022
Autor:
Laurie P Sutton, Brian S Muntean, Olga Ostrovskaya, Stefano Zucca, Maria Dao, Cesare Orlandi, Chenghui Song, Keqiang Xie, Kirill A Martemyanov
Publikováno v:
PLoS Biology, Vol 17, Iss 10, p e3000477 (2019)
The striatum plays a fundamental role in motor learning and reward-related behaviors that are synergistically shaped by populations of D1 dopamine receptor (D1R)- and D2 dopamine receptor (D2R)-expressing medium spiny neurons (MSNs). How various neur
Externí odkaz:
https://doaj.org/article/aa11db4ea136455e9a462b928d2d5b88
Akademický článek
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Autor:
Yasanandana S. Wijayasinghe, Meenakshi P. Bhansali, Maheshkumar R. Borkar, Ganesh U. Chaturbhuj, Brian S. Muntean, Ronald E. Viola, Pravin R. Bhansali
Publikováno v:
Journal of Medicinal Chemistry. 65:3706-3728
Glucose, the primary substrate for ATP synthesis, is catabolized during glycolysis to generate ATP and precursors for the synthesis of other vital biomolecules. Opportunistic viruses and cancer cells often hijack this metabolic machinery to obtain en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62bd32055fbe55274b047ad7d0d879b
https://doi.org/10.1021/acs.jmedchem.1c01737
https://doi.org/10.1021/acs.jmedchem.1c01737
Autor:
Laurie P Sutton, Cesare Orlandi, Chenghui Song, Won Chan Oh, Brian S Muntean, Keqiang Xie, Alice Filippini, Xiangyang Xie, Rachel Satterfield, Jazmine D W Yaeger, Kenneth J Renner, Samuel M Young Jr, Baoji Xu, Hyungbae Kwon, Kirill A Martemyanov
Publikováno v:
eLife, Vol 7 (2018)
Stress can be a motivational force for decisive action and adapting to novel environment; whereas, exposure to chronic stress contributes to the development of depression and anxiety. However, the molecular mechanisms underlying stress-responsive beh
Externí odkaz:
https://doaj.org/article/bc515a3f3b5740a393f3425dd4ab9426
Autor:
Hannah M. Stoveken, Kirill A. Martemyanov, Dipak N. Patil, Justin Shumate, Thomas D. Bannister, Timothy P. Spicer, Brian S. Muntean, Louis Scampavia, Virneliz Fernandez-Vega
Publikováno v:
SLAS Discov
Regulators of G protein signaling (RGS) proteins serve as critical regulatory nodes to limit the lifetime and extent of signaling via G protein-coupled receptors (GPCRs). Previously, approaches to pharmacologically inhibit RGS activity have mostly fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4c99e2a226d6835ee891d54d5d0ed43
https://doi.org/10.1177/24725552211020679
https://doi.org/10.1177/24725552211020679
Autor:
Brock Grill, Kirill A. Martemyanov, Andrew C. Giles, Brian S. Muntean, Maria Dao, Dandan Wang
Publikováno v:
Human Molecular Genetics. 31:510-522
GNAO1 encephalopathy is a neurodevelopmental disorder with a spectrum of symptoms that include dystonic movements, seizures and developmental delay. While numerous GNAO1 mutations are associated with this disorder, the functional consequences of path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39256787f25f7c6c679e52dffafc298
https://doi.org/10.1093/hmg/ddab235
https://doi.org/10.1093/hmg/ddab235
Autor:
Trevor B. Doyle, Brian S. Muntean, Karin F. Ejendal, Michael P. Hayes, Monica Soto-Velasquez, Kirill A. Martemyanov, Carmen W. Dessauer, Chang-Deng Hu, Val J. Watts
Publikováno v:
Cells, Vol 8, Iss 11, p 1468 (2019)
Adenylyl cyclase type 5 (AC5), as the principal isoform expressed in striatal medium spiny neurons (MSNs), is essential for the integration of both stimulatory and inhibitory midbrain signals that initiate from dopaminergic G protein-coupled receptor
Externí odkaz:
https://doaj.org/article/2816566697a9482f908b17dccf107e2f