Zobrazeno 1 - 10
of 518
pro vyhledávání: '"S. Mortimer"'
Autor:
Y. Verastegui, J. Cheng, K. Engel, D. Kolczynski, S. Mortimer, J. Lavigne, J. Montalibet, T. Romantsov, M. Hall, B. J. McConkey, D. R. Rose, J. J. Tomashek, B. R. Scott, T. C. Charles, J. D. Neufeld
Publikováno v:
mBio, Vol 5, Iss 4 (2014)
ABSTRACT Soil microbial diversity represents the largest global reservoir of novel microorganisms and enzymes. In this study, we coupled functional metagenomics and DNA stable-isotope probing (DNA-SIP) using multiple plant-derived carbon substrates a
Externí odkaz:
https://doaj.org/article/90080f163bda4d12a4b4150a2b74ee92
Autor:
René Hägerling, Malou Van Zanten, Rose Yinghan Behncke, Sascha Ulferts, Nils R. Hansmeier, Bruno Märkl, Christian Witzel, Bernard Ho, Vaughan Keeley, Katie Riches, Sahar Mansour, Kristiana Gordon, Pia Ostergaard, Peter S. Mortimer
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
Superficial erythematous cutaneous vascular malformations are assumed to be blood vascular in origin, but cutaneous lymphatic malformations can contain blood and appear red. Management may be different and so an accurate diagnosis is important. Cutan
Externí odkaz:
https://doaj.org/article/90a5b5d07dcd49ba99efb501fc892bb3
Autor:
Kristiana Gordon, Matthew Moore, Malou Van Zanten, Julian Pearce, Maxim Itkin, Brendan Madden, Lakshmi Ratnam, Peter S. Mortimer, Rani Nagaraja, Sahar Mansour
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The RASopathies are a group of genetic conditions resulting from mutations within the RAS/mitogen-activated protein kinase (RAS-MAPK) pathway. Lymphatic abnormalities are commonly associated with these conditions, however central conducting lymphatic
Externí odkaz:
https://doaj.org/article/53a4317ede384ad98e7ac6320078b63e
Autor:
Simon Smith, Woong-Yang Park, Kyoung-Mee Kim, Jeeyun Lee, Jung Yong Hong, Seung Tae Kim, Won Ki Kang, Emma Dean, Minsuk Kwon, Gahyun Kim, Ryul Kim, Kyu-Tae Kim, Peter G S Mortimer, Arsene-Bienvenu Loembé, Itziar Irurzun-Arana, Loumpiana Koulai
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background Targeting the DNA damage repair (DDR) pathways is an attractive strategy for boosting cancer immunotherapy. Ceralasertib (AZD6738) is an oral kinase inhibitor of ataxia telangiectasia and Rad3 related protein, which is a master regulator o
Externí odkaz:
https://doaj.org/article/0fb079375db848879a747baa38eb0c19
Autor:
Dionysios Grigoriadis, Ege Sackey, Katie Riches, Malou van Zanten, Glen Brice, Ruth England, Mike Mills, Sara E. Dobbins, Li Ling Lee, Steve Jeffery, Liang Dong, David B. Savage, Peter S. Mortimer, Vaughan Keeley, Alan Pittman, Kristiana Gordon, Pia Ostergaard
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Lipoedema is a chronic adipose tissue disorder mainly affecting women, causing excess subcutaneous fat deposition on the lower limbs with pain and tenderness. There is often a family history of lipoedema, suggesting a genetic origin, but the contribu
Externí odkaz:
https://doaj.org/article/690ab941e0c2484cbd480d1834ebbb70
Autor:
Koung Jin Suh, Min-Hee Ryu, Dae Young Zang, Woo Kyun Bae, Hye Seung Lee, Hyeon Jeong Oh, Minsu Kang, Ji-Won Kim, Bum Jun Kim, Peter G S Mortimer, Hee Jung Kim, Keun-Wook Lee
Publikováno v:
The Oncologist.
Background Loss of PTEN function leads to increased PI3Kβ signaling. AZD8186, a selective PI3Kβ/δ inhibitor, has shown anti-tumor activity in PTEN-deficient preclinical models. Although the combination of AZD8186 and paclitaxel was well tolerated,
Publikováno v:
Journal of pediatric orthopedics. Part B.
Supracondylar humerus fractures are common pediatric injuries encountered by orthopedic surgeons. Displaced fractures are treated operatively with closed reduction and percutaneous pinning or open reduction of injuries that cannot be adequately close
Autor:
Noeline Nadarajah, Mark D. Kilby, Maja Hempel, Stephanie E. Vallee, Silvia Martin-Almedina, Rhiannon Mellis, Dionysios Grigoriadis, Sarah Robart, Sahar Mansour, Mary Beth Dinulos, Ege Sackey, Giles Atton, Wolf-Henning Becker, Christina Karapouliou, Kazim Ogmen, Fanny Kortuem, Katherine S. Josephs, Gunnar Houge, Cathrine Ebbing, Pia Ostergaard, Kristiana Gordon, Steve Jeffery, Peter S. Mortimer, Jerome L. Gorski, Axel von der Wense, Alexandra Robinson, Cassandra Polun, Siren Berland, Jenny Lord, Hallvard Reigstad, Sherri J. Bale
Publikováno v:
Genetics in Medicine
PurposeSeveral clinical phenotypes including fetal hydrops, central conducting lymphatic anomaly or capillary malformations with arteriovenous malformations 2 (CM-AVM2) have been associated with EPHB4 (Ephrin type B receptor 4) variants, demanding ne
Autor:
Malou van Zanten, Kristiana Gordon, Sahar Mansour, Pia Ostergaard, Steve Jeffery, Peter S. Mortimer
Publikováno v:
Lymphatic Research and Biology. 19:25-30
Clinicians and scientists at St George's University Hospital have collaborated to develop a classification algorithm for primary lymphatic anomalies. Instruction is offered on how to apply the algorithm in clinical practice to refine the diagnosis of
Autor:
Simon D. French, Denise A. O’Connor, Sally E. Green, Matthew J. Page, Duncan S. Mortimer, Simon L. Turner, Bruce F. Walker, Jennifer L. Keating, Jeremy M. Grimshaw, Susan Michie, Jill J. Francis, Joanne E. McKenzie
Publikováno v:
Trials
Background Acute low back pain is a common condition, has high burden, and there are evidence-to-practice gaps in the chiropractic and physiotherapy setting for imaging and giving advice to stay active. The aim of this cluster randomised trial was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9284faa774299329554b50e0b527fbc4
https://openaccess.city.ac.uk/id/eprint/28294/1/s13063-022-06053-x.pdf
https://openaccess.city.ac.uk/id/eprint/28294/1/s13063-022-06053-x.pdf