Zobrazeno 1 - 10
of 83
pro vyhledávání: '"S. Milak"'
Autor:
Elizabeth A. Bartlett, Ashley A. Yttredahl, Maura Boldrini, Andrea E. Tyrer, Kathryn R. Hill, Mala R. Ananth, Matthew S. Milak, Maria A. Oquendo, J. John Mann, Christine DeLorenzo, Ramin V. Parsey
Publikováno v:
European Psychiatry, Vol 66 (2023)
Abstract Background Reported childhood adversity (CA) is associated with development of depression in adulthood and predicts a more severe course of illness. Although elevated serotonin 1A receptor (5-HT1AR) binding potential, especially in the raph
Externí odkaz:
https://doaj.org/article/0beaf2f9876840caa8cc2123d1a16faf
Autor:
Joshua T. Kantrowitz, Zhengchao Dong, Matthew S. Milak, Rain Rashid, Lawrence S. Kegeles, Daniel C. Javitt, Jeffrey A. Lieberman, J. John Mann
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-6 (2021)
Abstract Glutamate (Glu) and gamma-aminobutyric acid (GABA) are implicated in the pathophysiology of major depressive disorder (MDD). GABA levels or GABAergic interneuron numbers are generally low in MDD, potentially disinhibiting Glu release. It is
Externí odkaz:
https://doaj.org/article/45785de8c5354a3caf6214437af79f9f
Autor:
Zhengchao Dong, Michael F. Grunebaum, Martin J. Lan, Vashti Wagner, Tse-Hwei Choo, Matthew S. Milak, Tarek Sobeih, J. John Mann, Joshua T. Kantrowitz
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
N-methyl-D-aspartate glutamate-receptor (NMDAR) antagonists such as ketamine have demonstrated efficacy in both major depressive disorder (MDD) and bipolar disorder depression (BP-D). We have previously reported that reduction in Glx (glutamate + glu
Externí odkaz:
https://doaj.org/article/90870e5f05f849b0aa4d2ed27c3f7f09
Autor:
Harry Rubin-Falcone, Reuben Heyman-Kantor, Ainsley K. Burke, Jeffrey M. Miller, J. John Mann, Mina M. Rizk, Yashar Yousefzadeh Fard, Maria A. Oquendo, Francesca Zanderigo, Matthew S. Milak, M. Elizabeth Sublette, Gregory M. Sullivan
Publikováno v:
Journal of Affective Disorders. 280:105-113
It has been argued that unipolar major depressive disorder (MDD) and bipolar disorder (BD) exist on a continuous spectrum, given their overlapping symptomatology and genetic diatheses. The Bipolarity Index (BI) is a scale that considers bipolarity as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15aa93a459b3f80adc1016bfa6b96be9
https://doi.org/10.1016/j.jad.2020.10.071
https://doi.org/10.1016/j.jad.2020.10.071
Autor:
J.S. Dileep Kumar, Matthew S. Milak, Vattoly J. Majo, Jaya Prabhakaran, Pratap Mali, Lyudmila Savenkova, J. John Mann, Ramin V. Parsey
Publikováno v:
Journal of Pharmacological Sciences, Vol 120, Iss 3, Pp 254-257 (2012)
Serotonin (5-HT) 1A receptors exist in high and low affinity states. Agonist ligands bind preferentially to the high affinity state receptors, providing a more functionally relevant measure than antagonist binding. We now report comparison of 5-HT1A
Externí odkaz:
https://doaj.org/article/40a631a8e76d4b60940a1e8ca271c126
Publikováno v:
NMR in biomedicineREFERENCES. 35(6)
In proton magnetic resonance spectroscopy (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37156074473be8f5e5a6a5506d9f6702
https://pubmed.ncbi.nlm.nih.gov/34961997
https://pubmed.ncbi.nlm.nih.gov/34961997
Autor:
Zhengchao Dong, Jeffrey A. Lieberman, J. John Mann, Matthew S. Milak, Joshua T. Kantrowitz, Daniel C. Javitt, Lawrence S. Kegeles, Rain Rashid
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 11, Iss 1, Pp 1-6 (2021)
Translational Psychiatry, Vol 11, Iss 1, Pp 1-6 (2021)
Glutamate (Glu) and gamma-aminobutyric acid (GABA) are implicated in the pathophysiology of major depressive disorder (MDD). GABA levels or GABAergic interneuron numbers are generally low in MDD, potentially disinhibiting Glu release. It is unclear w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb817dae02a2f9a30de39e73f3639ee5
https://doi.org/10.1038/s41398-021-01541-1
https://doi.org/10.1038/s41398-021-01541-1
Autor:
Holly Brandenburg, John G. Keilp, Martin Schain, W. Antonio Potter, Francesca Zanderigo, Ramin V. Parsey, J. John Mann, M. Elizabeth Sublette, Kevin M. Malone, Matthew S. Milak, Spiro P. Pantazatos, Maria A. Oquendo
Publikováno v:
Psychiatry Research: Neuroimaging. 283:96-103
Memory deficits are reported in major depressive disorder (MDD). Prefrontal cortical and mesiotemporal cortical (MTC)/subcortical regions are involved in the Buschke Selective Reminding Task (SRT), a verbal list-learning task. To determine whether de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efcfb255bb9161169cd72781af764bc9
https://doi.org/10.1016/j.pscychresns.2018.12.006
https://doi.org/10.1016/j.pscychresns.2018.12.006
Autor:
M. Elizabeth Sublette, Steven P. Ellis, John G. Keilp, Julia E. Marver, Matthew S. Milak, Ainsley K. Burke, Maria A. Oquendo, Michael F. Grunebaum, J. John Mann, Thomas B. Cooper, Vivek K. Moitra
Publikováno v:
Bipolar Disorders. 19:176-183
Objectives To evaluate feasibility and effects of a sub-anesthetic infusion dose of ketamine versus midazolam on suicidal ideation in bipolar depression. Neurocognitive, blood and saliva biomarkers were explored. Methods Sixteen participants with bip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c77210618197f4e9f014f4b4ff2e3de
https://doi.org/10.1111/bdi.12487
https://doi.org/10.1111/bdi.12487
Autor:
Stephanie T. Mulhern, Matthew S. Milak, Zhengchao Dong, Dikoma C. Shungu, J. John Mann, Raymond F. Suckow, Lawrence S. Kegeles, John G. Keilp, Rain Rashid, Xuejing Lin, R. Todd Ogden, Michael F. Grunebaum, Xiangling Mao, Thomas B. Cooper
Publikováno v:
JAMA Network Open. 3:e2013211
Importance A single subanesthetic dose of ketamine produces an antidepressant response in patients with major depressive disorder (MDD) within hours, but the mechanism of antidepressant effect is uncertain. Objective To evaluate whether ketamine dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34d7c6f0611983721b1e521047c2525c
https://doi.org/10.1001/jamanetworkopen.2020.13211
https://doi.org/10.1001/jamanetworkopen.2020.13211