Zobrazeno 1 - 10
of 90
pro vyhledávání: '"S. Michael Owens"'
Autor:
Lisa Brents, Bryce A. Griffin, Caitlin Caperton, Lauren Russell, Christian Cabanlong, Catheryn Wilson, Kyle Urquhart, Brad Martins, Amy L. Patton, Alexander W. Alund, S. Michael Owens, William E. Fantegrossi, Jeffery H. Moran
Publikováno v:
Journal of Clinical and Translational Science, Vol 2, Pp 9-9 (2018)
OBJECTIVES/SPECIFIC AIMS: Rodent models can be used to study neonatal abstinence syndrome (NAS), but the applicability of findings from the models to NAS in humans is not well understood. The objective of this study was to develop a rat model of norb
Externí odkaz:
https://doaj.org/article/25671ece437a4569adbe207ce421025f
Autor:
Michael D Hambuchen, Michael D Berquist, Christy M Simecka, Mitchell R McGill, Melinda G Gunnell, Howard P Hendrickson, S Michael Owens
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 22, Iss 1 (2019)
Purpose: Methamphetamine (METH) abuse is associated with hepatic dysfunction related comorbidities such as HIV, hepatitis C, and polysubstance abuse with acetaminophen-containing opioid formulations. We aimed to develop a bile duct ligation (BDL)-ind
Externí odkaz:
https://doaj.org/article/f7afe7f33588490594ed5cde539341a7
Autor:
Charles E Hay, Guillermo A Gonzalez, Laura E Ewing, E Elizabeth Reichard, Michael D Hambuchen, Nisha Nanaware-Kharade, Sinthia Alam, Chris T Bolden, S Michael Owens, Paris Margaritis, Eric C Peterson
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0200060 (2018)
Methamphetamine (METH) substance abuse disorders have major impact on society, yet no medications have proven successful at preventing METH relapse or cravings. Anti-METH monoclonal antibodies can reduce METH brain concentrations; however, this thera
Externí odkaz:
https://doaj.org/article/a3b7cda581564b6da93d3379f3633e3c
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: 3,4-Methylenedioxypyrovalerone (MDPV) is a synthetic cathinone abused for its cocaine-like psychostimulant effects in “bath salts” products. While there are currently no pharmacotherapies for MDPV abuse, rodent studies suggest immunoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f33af33924c30f470c21fbde204a0b3
https://doi.org/10.1007/s00213-020-05558-0
https://doi.org/10.1007/s00213-020-05558-0
Autor:
Andrew C Harris, Mark G LeSage, David Shelley, Jennifer L Perry, Paul R Pentel, S Michael Owens
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138959 (2015)
Externí odkaz:
https://doaj.org/article/4f8a764aa0714531a0964963584adb07
Autor:
Andrew C Harris, Mark G LeSage, David Shelley, Jennifer L Perry, Paul R Pentel, S Michael Owens
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118787 (2015)
Passive immunization with monoclonal antibodies (mAbs) against (+)-methamphetamine (METH) is being evaluated for the treatment of METH addiction. A human/mouse chimeric form of the murine anti-METH mAb7F9 has entered clinical trials. This study exami
Externí odkaz:
https://doaj.org/article/dc8054b2511442b08a2ff0d28b49e3cb
Publikováno v:
J Pharm Pharm Sci
Journal of Pharmacy & Pharmaceutical Sciences, Vol 24, Iss 3 (2021)
Journal of Pharmacy & Pharmaceutical Sciences, Vol 24, Iss 3 (2021)
PURPOSE: α-Pyrrolidinovalerophenone (α-PVP) is a second-generation synthetic cathinone which acts as an inhibitor at the dopamine and norepinephrine transporters in the brain. These novel studies determined the pharmacokinetics (PK) of α-PVP in ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd30d98ab3b7bb0c0cd0d775ee12755
https://pubmed.ncbi.nlm.nih.gov/34062113
https://pubmed.ncbi.nlm.nih.gov/34062113
Autor:
Michael D. Berquist, S. Michael Owens, Samantha J. McClenahan, Michael D. Hambuchen, Christy M Simecka, Melinda G. Gunnell
Publikováno v:
Drug and Alcohol Dependence. 195:140-147
BACKGROUND: 3,4-methylenedioxypyrovalerone (MDPV) toxicity includes intense neurological and cardiovascular events. We examined MDPV-induced cardiovascular, temperature, and locomotor effects following escalating and repeated MDPV administration in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a851d86855c92fd2834010d4fc62ee8
https://doi.org/10.1016/j.drugalcdep.2018.12.006
https://doi.org/10.1016/j.drugalcdep.2018.12.006
Autor:
Eric C. Peterson, Michael D. Hambuchen, William E. Fantegrossi, Laura E. Ewing, Chris Bolden, Juliana C. Small, S. Michael Owens, Shannon M. Zintner, Charles E. Hay, Paris Margaritis
Publikováno v:
J Pharmacol Exp Ther
Methamphetamine (METH) continues to be among the most addictive and abused drugs in the United States. Unfortunately, there are currently no Food and Drug Administration–approved pharmacological treatments for METH-use disorder. We have previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f9ec0f295f976f25a681a4752579cf3
https://europepmc.org/articles/PMC7289050/
https://europepmc.org/articles/PMC7289050/
Publikováno v:
Analytical Methods. 9:609-617
The emerging stimulant drug of abuse (3,4)-methylenedioxypyrovalerone [(R,S)-MDPV] is self-administered as a racemic mixture by intranasal, iv, oral, and smoking routes. The individual enantiomers are known to have widely different pharmacological ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf5e8800498097873c18da6e2979b60
https://doi.org/10.1039/c6ay03176e
https://doi.org/10.1039/c6ay03176e